• Fully automated Liquid Handling device    (System from Caliper Life sciences)

  • Caliper Liquid Handling (96 and 384 array head): 0.1 µl – 5 µl volume
  • Temperature + CO2 controlled incubator: temperature range 23°C – 40°C
  • Integrated Dispensers (2 x PE Flexdrop)
  • Integrated Washer (Biotek ELx405)
  • Integrated plate reader (PE EnVision)
  • Robotic arm => full automation

• Perkin Elmer EnVision multilabel plate reader (Second reader – stand alone)

  • Fluorescence (monochromator + filter-based)
  • Time-resolved fluorescence (TRF)
  • AlphaScreen technology
  • Luminescence
  • Absorbance (monochromator + filter-based)

Perkin Elmer Operetta High Content Screening System

• Confocal microscope with temperature control            
• 4x, 10x, 20x, 40x objectives and                     40x, 60x high NA objectives
• Different filter sets (Hoechst, CFP, Green, YFP, Red, Deep Red)
• Automated stage for 96 and 384 plates
• Software for automated evaluation of screening data

NanoTemper Monotith Microscale Thermophoresis (MST) device

• Measurement of protein-protein                  interactions

• Measurement of protein-compound              interactions
• Measurement of protein-nucleic acid              interactions

• Peqlab Nanodrop 2000 spectrophotometer

  • Full spectral output
  • Measures DNA, RNA (A260) and Protein (A280) concentrations
  • Pre-configured methods (Bradford, BCA, Lowry and Pierce)