cooperation group "comprehensive molecular analytics"

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Analytical Instrumentation Available at the Cooperation Group

Standard instrumentation

  • two HPLC-MS/MS systems
  • two HPLC systems equipped with diode array and fluorescence detector
  • one system for multi dimensional gas chromatography - time-of-flight mass spectrometry (GC x GC - TOFMS)
  • four GC-MS systems (one TOF, three for thermo desorption)
  • several instruments coupled for thermal analysis (TG, DSC, etc.) with EI - quadrupole mass spectrometry and FTIR

Instrumentation for physicochemical characterization of aerosol particles

  • a high resolution aerosol mass spectrometer (AMS)
  • a single particle time-of-flight mass spectrometer (A-TOF)
  • particle sizing instruments: scanning mobility particle sizers (SMPS), electric low pressure impactors (ELPI), aerodynamic particle sizers (APS), white light optical particle sizer (WELAS), mass sampling equipment (Berner impactors, rotating-drum impactor, MOUDI impactor, low volume samplers)

Instrumentation for the development of analytical methods

  • laser desorption / thermodesorption - resonance enhanced multiphoton ionization - single particle - time of flight mass spectrometer (LD-/TD-REMPI-SP-TOFMS)
  • laser-desorption ionization / laser-desorption resonance enhanced - multiphoton ionization / single-photon ionization - time of flight mass spectrometer (LDI/LD-REMPI/SPI-TOFMS) for the analysis of solid samples, sampled aerosol particles and biological samples
  • thermal analysis - single-photon ionization - quadrupole mass spectrometer (TA-SPIxMS)  and a thermal analysis - single-photon ionization - time of flight mass spectrometer (TA-SPI-TOFMS)  for the determination of organic signatures
  • three instruments for multi-dimensional analysis of highly complex samples in bio- and environmental science: thermal analysis - single-photon ionization comprehensively coupled with gas chromatography time of flight mass spectrometry (TA-GCxSPI-TOFMS), gas chromatography - EBEL-single-photon ionization - time of flight mass spectrometry (GCxSPI-TOFMS) and comprehensive two-dimensional gas chromatography - EBEL-single-photon ionization - time of flight mass spectrometry (GCxGC-SPI-TOFMS)
  • two thermodesorption - photo ionization -  ion trap - mass spectrometers (TD-SPI-ITMS) for the determination of security-relevant compounds (drugs, explosive substances etc.)
     

Lung Deposition Modeling

For the interactive modeling of particle deposition in the lungs, the HPLDB Model of George A. Ferron is available to calculate the regional deposition of monodisperse particles in the lungs.