computational
modeling in
biology

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Dominik Wittmann

Dipl. Math.
PhD student


Tel.: +49 (0) 89 3187 4217
Room: 136a


Research

  • Generalizations of Boolean logic models
  • Topological reverse engineering
  • Quantification of discrete models
  • Gene regulation the Mid-/hindbrain boundary
  • Parameter fitting in biological systems

 

Publications

  • Blöchl F, Wittmann DM (equal contributor) and Theis FJ. Effective parameters determining the information flow in hierarchical biological systems. in revision
  • Krumsiek J, Pölsterl S, Wittmann DW and Theis FJ. Odefy - From discrete to continuous models. submitted
  • Wittmann DM, Blöchl F, Trümbach D, Wurst W, Prakash N and Theis FJ. Spatial Analysis of Expression Patterns Predicts Genetic Interactions at the Mid-Hindbrain Boundary. PLoS Comput Biol 5:11, 2009 [PubMed]
  • Wittmann DM, Krumsiek J, Saez-Rodriguez J, Lauffenburger DA, Klamt S and Theis FJ. Transforming Boolean Models to Continuous Models: Methodology and Application to T-Cell Receptor Signaling. BMC Syst Biol 3:98, 2009 [PubMed]
  • Wittmann DM, Schmidl D, Blöchl F and Theis FJ. Reconstruction of graphs based on random walks. J Theor Comput Sci 410, 2009

 

Curriculum Vitae

Dominik Wittmann studied mathematics at the University of Regensburg and at Brandeis University. He also took economics and actuarial sciences as minor subjects. Of particular interest to him were Number Theory and Algebraic Geometry. His diploma thesis is about Igusa zeta functions of Fermat Varieties.

He graduated in 2007 and is currently working as a PhD student at the Institute of Bioinformatics and Systems Biology, located at the Helmholtz Research Center Munich.