diabetes research department

Basis

Projects:

  • Effects of nutrition on metabolism
  • Role of mitochondria in the pathogenesis and disease course of diabetes
  • Relationships between arteriosclerosis, liver, kidney, thyroid gland and diabetes development
  • Genetische Determination verschiedener Subtypen von Diabetes
  • Genetic determination of different subtypes of diabetes
  • Association between diabetes risk and gender
  • Central nervous control of systems metabolism

Successes:

  • Elucidation of the functions of genes
  • Relationship of smoking and diabetes
  • Relationship of birth weight and diabetes
  • Genetic causes identified for disturbances in the lipid metabolism


New Approaches to Therapy

Projects:

  • Specific nutritional forms for diabetes intervention
  • Possibilities of regeneration of beta cells and approaches to stem cell therapy
  • Vaccination study for type 1 diabetes
  • Polypharmacy for treatment of diabetes and obesity

Successes:

  • Immunotherapy for type 1 diabetes


New Diagnostic Methods

Projects:

  • Measurement of risk factors for diabetes in the exhaled air
  • Early diagnosis through metabolites in the blood

Successes:

  • New markers for early detection of type 1 diabetes mellitus


New Prevention Strategies

Projects:

  • Influence of lifestyle factors such as nutrition, exercise etc. on the course of disease
  • Nutritional intervention in carriers of risk gene variants
  • Changes in gene expression depending on diabetes status and genetic profile

Successes:

  • Genetic risk factors identified for type 1 and type 2 diabetes
  • Vitamin D may reduce diabetes risk


Health Care Research

Projects: 

  • Benefit analysis of disease management programs
  • Diabetes and social imbalances
  • Influence of mental state/depression on the course of disease

Successes:

  • Benefit of disease management programs is confirmed

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