Mouse Genetics
The IDG Mouse Genetics Group generates targeted mouse mutants for internal scientific projects and external collaborations. The Large Scale Mutagenesis Team participates in the international EUCOMM large scale mutagenesis program to create a genome-wide resource of conditional targeted ES cells and mice. Within the national DIGTOP (disease genes to proteins) project the proteomic interactions of disease-related genes in stem cells and mice are analysed. The Technology Development and Animal Model Generation teams develop new mutagenesis tools and provide infrastructure and a microinjection service for the generation of mouse mutants. The Bioinformatics team develops data infrastructures for the high-throughput analysis of mouse mutants and is involved in the modelling of genetic and protein interaction networks.