institute of experimental genetics (ieg)

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Head of the Institute of Experimental Genetics

Director of the IEG

Prof. Dr. Martin Hrabé de Angelis
hrabe@helmholtz-muenchen.de

 

Deputy director of the IEG

Priv.-Doz. Dr. Johannes Beckers, Executive MBA
beckers@helmholtz-muenchen.de

 

 


Groups

Diabetes models

Head of the group: Dr. Susanne Neschen

Keywords: mouse models, diabetes mellitus, type 2 diabetes, glucose homeostasis, lipid homeostasis, insulin action, β-cell function, therapeutic intervention, environmental challenges, hepatic insulin resistance, GMC Diabetes Screen, glucose clamps

 

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Translational Diabetology

Head of the group: Prof. Dr. med. Dr. h.c. Hans-Ulrich Häring

Keywords: Prediabetes, biomarkers, metabolically malign and benign obesity, responder/non-responder to lifestyle intervention, insulin resistance, human biomaterial (adipose tissue and skeletal muscle), “omics”

 

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Gene regulation

Head of the group: Priv.-Doz. Dr. Johannes Beckers

Keywords: gene regulation, mouse models, transcriptomics, miRNAs, data integration, epigenetics, metabolic diseases, diabetes, maternal inheritance

 

 

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Molecular endocrinology

Head of the group: Prof. Dr. Dr. Jerzy Adamski

Keywords: lipidomics, lipid and steroid metabolism, adipogenesis, diabetes, obesity, steroid-related diseases, metabolic syndrome, metabolic diseases, biomarkers, drug development

 

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Functional genetics

Head of the group: Prof. Dr. Martin Hrabě de Angelis

Senior Staff Scientist: Dr. Gerhard Przemeck

Keywords Metabolism & Disease: mouse models; metabolic diseases; bone-related diseases; diabetes; Delta-Notch; in silico modeling

More information on Metabolism & Disease

Senior Staff Scientist: Dr. Sibylle Wagner

Keywords Mouse Mutagenesis: ENU mutagenesis, F1-DNA archive, mouse models, bone and metabolic diseases, SNP platform

More information on the Munich ENU Mutagenesis Project (MEP)

 


German Mouse Clinic (GMC)

Head of the group: Prof. Dr. Martin Hrabe de Angelis, Dr. Valerie Gailus-Durner, Dr. Helmut Fuchs

Keywords: open access phenotyping, comprehensive phenotyping, mouse models, pathophysiology of diseases, diabetes, metabolic syndrome and neurodegenerative diseases

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Applied bioinformatics (within GMC)

Head of the group: Dr. Christoph Lengger, Dr. Holger Maier

Keywords: Standardized description of mouse phenotypes, software development, database development, open-source software, data management, LIMS, statistical analysis of phenotyping results, development of new statistics methods

 

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Platforms

European Mouse Mutant Archive (EMMA) & Cryo preservation

Head of the group: Dr. Michael Hagn & Dr. Susan Marschall

Keywords: sperm freezing, embryo freezing, in vitro fertilisation, embryo transfer, cryopreservation; functional genomics; mouse mutants; disease models; mouse repository

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Genome Analysis Center (GAC)

Head of the group: Prof. Dr. Jerzy Adamski, Prof. Dr. Thomas Illig (Deputy)

Keywords: Genome, high-throughput, HTP, omics, genotyping, DNA sequencing, transcriptomics, proteomics, metabolomics, complex diseases

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More details on sample preparation requirements, analytical portfolio, support possibilities and research are available under www.gac-munich.de

 


EU research infrastructure

Infrafrontier

Head of the group: Dr. Michael Räß

Keywords: ESFRI, research infrastructure, disease models, systemic phenotyping, functional genomics, open access, GMC, EMMA

 

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