Postal address:

Helmholtz Zentrum München
German Research Center for Environmental Health
Institute of Health Economics and Health Care Management (IGM)
P.O.Box 1129
D-85758 Neuherberg
Germany
Tel.: +49-89 / 3187-4192
Fax: +49-89 / 3187-3375
eMail: holle@helmholtz-muenchen.de 

Prof. Dr. Rolf Holle

Position:

Head of research group and of KORA Statistics and Data Center
and Deputy Director of the Institute

Education:

• Diploma in mathematics at University of Marburg
• Ph.D. at Medical Faculty, University of Giessen
• Habilitation for Medical Biometry at University of Heidelberg
• Professorship (apl) at Medical Faculty, Ludwig Maximilian University Munich

Continuing education:

• Certificate for medical Biometry of the GMDS
• York Expert Workshop on "Advanced methods for cost-effective analysis" (2004)

Research interests:

• Economic evaluation in clinical trials
• Issues in diagnostic and prognostic modelling
• Health survey methodology

Recent publications:

2011:

• Hunger, M., Baumert, J., Holle, R.: Analysis of SF-6D index data: Is beta regression appropriate? Value in Health (im Druck, 2011)
• Stark, R., Schunk, M., Meisinger, C., Rathmann, W., Leidl, R., Holle, R.  Medical care of type 2 diabetes in German disease management programs: a population-based evaluation. Diabetes/Metabolism Research and Reviews (im Druck, 2011)

2010:

• Bierwirth, R.A., Kohlmann, T., Moock, J, Holle, R., Landgraf, W.: Diabetesbezogene Kosten und Therapiezufriedenheit bei ICT-behandelten Typ 2-Diabetikern in der ambulanten Versorgung – Ergebnisse der LIVE-COM Studie. Med. Klinik 105, 792-801 (2010)
• Donath, C., Gräßel, E., Großfeld-Schmitz, M., Menn, P., Lauterberg, J., Wunder, S., Marx, P., Ruckdäschel, S., Mehlig, H., Holle, R.: Effects of general practitioner training and family support services on the care of home-dwelling dementia patients – Results of a controlled cluster-randomized study. BMC Health Services Research 10: 314 (2010)
• Grossfeld-Schmitz, M., Donath, C., Holle, R., Lauterberg, J., Ruckdäschl, S., Mehlig, H., Marx, P., Wunder, S., Gräßel, E.: Counsellors Contact Dementia Caregivers – Predictors of Utilisation in a Longitudinal Study. BMC Geriatrics 10:24 (2010)
• Kirchberger, I., Meisinger, C., Seidl, H., Wende, R., Kuch, B., Holle, R.: Nurse-based case management for aged patients with myocardial infarction – study protocol of a randomized controlled trial. BMC Geriatrics 10:29 (2010)
• Menn, P., Weber, N., Holle, R.: Quality of life in patients with severe COPD hospitalized for exacerbations – comparing EQ-5D, SF-12 and SGRQ. Health and Quality of Life Outcomes 8:39 (2010)
• Stollenwerk, B., Stock, S., Siebert, U., Lauterbach, K.W., Holle, R.: Uncertainty assessment of input parameters for economic evaluation: Gauss’ error propagation, an alternative to established methods. Medical Decision Making 30, 304-313 (2010)

2009:

• Haucke, F., Holle, R., Wichmann, H.E.: Epidemiologische Erforschung und ökonomische Bewertung gesundheitlicher Umweltrisiken. Bundesgesundheitsblatt 52, 1166-1178 (2009)
• Holle, R., Gräßel, E., Ruckdäschel, S., Wunder, S., Mehlig, H., Marx, P., Pirk, O., Butzlaff, M., Kunz, S., Lauterberg, J.: Dementia care initiative in primary practice – Study design of a cluster randomized trial on dementia management in a general practice setting. BMC Health Services Research 9, 91 (2009)
• Menn, P., Holle, R.: Comparing three software tools to implement Markov models for health economic evaluations. Pharmacoeconomics 27, 745-753 (2009)
• Neubauer, S., Holle, R., Menn, P., Gräßel, E.: A valid instrument for measuring informal care time for demented people. International Journal of Geriatric Psychiatry 24, 275-82 (2009)
• Schunk, M., Schweikert, B., Gapp, O., Reitmeir, P., Meisinger, C., Mielck, A., Holle, R.: Time trends in type 2 diabetes patients’ disease management and outcomes: evidence from two KORA surveys in Germany. Exp. Clin.Endocrin. Diab. 117, 88-94 (2009)
• Schweikert, B., Hunger, M., Meisinger, C., König, H.H., Gapp, O., Holle, R.: Quality of life several years after myocardial infarction: comparing the MONICA/KORA registry to the general population. Eur Heart J 30, 436-443 (2009)
• Stark, R., Schunk, M., Leidl, R., Meisinger, C., Holle, R.: Prozessevaluation von Disease Management Programmen bei Typ 2 Diabetes auf Basis einer bevölkerungsrepräsentativen Studie in der Region Augsburg (KORA). Betriebswirtschaftliche Forschung und Praxis 61, 283-301 (2009)
 

Current teaching responsibilities:

• Lectures on economic evaluation methods, reliability studies, statistical quality control, evaluation of diagnostic tests at the Medical Faculty of the LMU Munich as part of the Postgraduate Education Program "Public Health and Epidemiology"
• Research seminar on health Economics and Management (with R. Leidl)

Activities in boards and scientific associations:

• Member of the GMDS, the German Region of the IBS and of the ISCB
• Speaker of Fachbereich Medical Biometry of the GMDS (2002-2004)
• Member of several Review Panels for the BMBF, the DFG, the Alexander-von-Humboldt-Foundation, the German Cancer Society
• Member of Advisory Boards of several clinical studies
• Reviewer for several scientific journals (i.a. Pharmacoeconomics, Medical Care, Statistics in Medicine, BMC Public Health, European Journal of Cancer, Methods of Information in Medicine, BMC Health Services Research, American Journal of Epidemiology, European Journal of Health Economics)

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