Developmental Projects

Innovative approaches to the development of new and optimized drugs

Helmholtz Zentrum München focuses on supporting promising projects that are in the early stage of the value chain. These include projects in the field of drug discovery with innovative target structures and test systems to identify and develop effective and safe drugs for chronic, complex diseases. The portfolio of Helmholtz Zentrum München currently comprises development projects from the areas of diabetes, neurodegeneration, infectious diseases and cancer, such as:

  • New strategies to activate central signaling pathways in the regulation of the lipid and energy metabolism for the treatment of obesity and diabetes differentiation of embryonic stem cells into insulin-producing beta-cells
  • Identification of new drugs to combat neurodegenerative diseases
  • Identification of new HIV inhibitors through innovative test systems
  • Development of selective inhibitors of gene regulation in cancer
  • Inhibition of target structures in B-cell activation for the treatment of B-cell lymphoma
  • Development of bi-specific aptamers to combat B-cell lymphomas
  • New approaches to inhibit EBV-induced B-cell immortalization