institute of
radiation biology

The DoReMi Network of Excellence

The European Network of Excellence DoReMi addresses the health risks of low doses of ionising radiation such as those that are encountered in the environment, occupationally and in the course of medical diagnostic procedures. DoReMi was launched in January 2010 with 12 original partners, with a duration of six years. In July 2011, 10 new partners joined the consortium as a result of DoReMi's first competitive call.
The purpose of DoReMi is to promote the sustainable integration of low dose risk research in Europe in order to aid the effective resolution of the key policy questions identified by the High Level Expert Group (HLEG) on Low Dose Risk Research.
DoReMi provides an operational tool for the development of the proposed MELODI platform (Multidisciplinary European Low Dose Risk Research Initiative) consisting of major national bodies and research programmes that have long term commitment in low dose risk research in Europe.   In addition to our contribution to various DoReMi research projects, the Institute of Radiation Biology provides Training for MSc and PhD students.

Radiation Epidemiology and Radio-Ecology (13.02.2012 – 02.03.2012)

During the lectures, seminars and lab visits of the course the participants will be introduced into general methods of medical epidemiology, measurements of radiation exposure and retrospective dose assessments, quantification of radiation late effects and calculation of risk factors, distribution of radioisotopes in the environment and their monitoring. Special focus will be given to recent issues of radioactive contaminations such as after the Chernobyl accident and the Fukushima disaster.  Observations on occupational and medical exposed cohorts with regard to late malignancies and non-cancer effects will be critically evaluated.
During the course several sites of radiation exposure will be visited (such as to a nuclear power plant and to a medical radium spa), where environmental samples will be collected for a subsequent  measurement.

In addition to teaching state-of-the art knowledge of radiation epidemiology and radio-ecology, lecturers from various European universities and institutes will also provide the students with an exclusive insight into their own research projects.

Molecular mechanisms of radiation carcinogenesis (30.04.2012 – 11.05.2012)

The scope of this two-week course is to provide advanced training by lecture and laboratory work in the molecular processes that are involved in the development of spontaneous and radiation-induced cancer.  Our course will place special emphasis on cancers of tissues where there is strong evidence for radiation-induced cancers (e.g. the lymphopoietic system, thyroid, breast). The course will consist of 4 teaching and 1 laboratory units dealing with:

  • Research tools
  • Basics of cancer development
  • Multi-step model of carcinogenesis and heritable effects
  • Molecular biology of selected Tumor-types
  • Radiation-induced cancers
  • Key issues facing radiation cancer research
  • Molecular techniques for analysis of radiation-induced changes in the transcriptome, epigenome and proteome.
  • The course will be completed by a field trip to the radiation oncology facilities of the Technical University medical school.