institute of stem cell research

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Institute of Stem Cell Research

 

AG 2: Hämatopoese > Homepage von Michael Rieger

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Curriculum Vitae

  • Since summer 2005: PostDoc of the independent research group for Hematopoiesis at the Institute of Stem Cell Research, Helmholtz Zentrum München – German Research Center for Environmental Health
    Long-term time-lapse bioimaging of single hematopoietic stem cells: Novel insights into the control of fate decisions

  • 2004-2005: PostDoc at the Institute of Immunology , Medical Faculty Carl-Gustav-Carus, Technical University of Dresden, Germany
    Identification and validation of novel tumour-associated proteins for therapy and diagnosis of cancer

  • 2001-2004: Ph.D. thesis at the Institute of Immunology , Medical Faculty Carl-Gustav-Carus, Technical University of Dresden, Germany:
    “CYP4Z1 and CYP4Z2P: Identification of novel members of the human cytochrome P450 family with preferential expression in mammary gland and breast carcinoma“
    (summa cum laude)

  • 1995-2000: Study in Biology at the Ludwig-Maximilians-University in Munich, Germany
    with specialisation in Human Genetics, Immunology, Biochemistry and Genetics

    • Diploma thesis at the Institute of Molecular Immunology , Helmholtz Zentrum München – German Research Center for Environmental Health: “Molecular and functional analyses of tumour-infiltrating lymphocytes of a prostate carcinoma”


Patent Applications

  • "Breast Specific Protein Expressed in Cancer and Methods of Use Thereof"
    International Publication Number WO2004058167

 

Travel/Conference Awards

  • 2003
    European Union (EU) Conference Grant
    “13th International Conference on Cytochromes P450” in Prague, Czech Republic
  • 2004 GlaxoSmithKline Travel Award
    “Microsomes and Drug Oxidations 2004” in Mainz, Germany
  • 2006
    Poster Award of the German Academy of Science Leopoldina
    “Embryonic and Somatic Stem Cells – Regenerative Systems for Cell and Tissue Repair” in Dresden, Germany
  • 2007
    GlaxoSmithKline Travel Award
    “ISSCR annual meeting 2007” in     Cairns, Australia
  • 2007
    International Society of Stem Cell Research (ISSCR) Travel Award
    “ISSCR annual meeting 2007” in     Cairns, Australia
  • 2007
    International Society of     Experimental Hematology (ISEH) Travel Award
    “ISEH annual meeting 2007” in     Hamburg, Germany
  • 2007
    Nominee for the international New Investigator Award of the International Society for Experimental Hematology (ISEH) in Hamburg

 

Research Publications (in chronological order)

  • Temme, A., Rieger, M., Reber, F., Lindemann, D., Weigle, B., Diestelkoetter-Bachert, P., Ehninger, G., Tatsuka, M., Terada, Y., and Rieber, E.P. (2003)
    Localisation, dynamics and function of Survivin revealed by expression of functional SurvivinDsRed fusion proteins in the living cell.
    Mol. Biol. Cell., 14, 78-92
  • Rieger, M.A. , Ebner, R., Bell , D.R., Kiessling, A., Rohayem, J., Schmitz, M., Temme, A., Rieber, E.P., and Weigle, B. (2004)
    Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma.
    Cancer Res., 64, 2357-2364
  • Kiessling, A., Stevanovic, S., Füssel, S., Weigle, B., Rieger, M.A., Temme, A., Rieber, E.P., and Schmitz, M. (2004)
    Identification of an HLA-A*0201-restricted T cell epitope derived from the prostate cancer-associated protein prostein.
    Br. J. Cancer, 90, 1034-1040
  • Weigle, B., Kiessling, A., Ebner, R., Fuessel, S., Temme, A., Schmitz, M., Rieger, M.A., Ockert, D., Wirth, M.P., and Rieber, E.P. (2004)
    D-PCa-2    : a novel transcript specifically expressed in human normal prostate and prostate cancer.
    Int. J. Cancer, 109, 882-892
  • Weigle, B., Fuessel, S., Ebner, R., Temme, A., Schmitz, M., Schwind, S., Kiessling, A., Rieger, M.A., Meye, A., Bachmann, M., Wirth, M.P., and Rieber, E.P. (2004)
    D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate.
    Biochem. Biophys. Res. Commun. , 322, 239-249
  • Weigle, B., Ebner, R., Temme, A., Schwind, S., Schmitz, M., Kiessling, A., Rieger, M.A., Schackert, G., Schackert, H.K., and Rieber, E.P. (2005)
    Highly specific overexpression of the transcription factor SOX11 in human malignant gliomas.
    Oncol. Rep., 13, 139-144
  • Temme, A., Morgenroth, A., Diestelkoetter-Bachert, P., Weigle, B., Rieger, M.A., Kiessling, A., Schmitz, M., and Rieber, E.P. (2005)
    Increased p21ras activity in human fibroblasts transduced with Survivin enhances cell proliferation.
    Biochem. Biophys. Res. Commun., 327, 765-773
  • Temme, A., Herzig, E., Weigle, B., Morgenroth, A., Schmitz, M., Kiessling, A., Rieger, M.A., Schackert, H.K., and Rieber, E.P. (2005)
    Inhibition of malignant glioma cell growth by a survivin mutant retrovirus.
    Hum. Gene. Ther. , 16, 209-222
  • Schmitz, M., Zhao, S., Deuse, Y., Schäkel, K., Wehner, R., Wöhner, H., Hölig, K., Wienforth, F., Kiessling, A., Bornhäuser, M., Temme, A., Rieger, M.A., Weigle, B., Bachmann, M., and Rieber, E.P. (2005)
    Tumoricidal potential of native blood dendritic cells: direct tumor cell killing and activation of NK cell-mediated cytotoxicity.
    J. Immunol., 174, 4127-4134
  • Kiessling, A., Weigle, B., Füssel, S., Ebner, R., Meye, A., Rieger, M.A., Schmitz, M., Temme, A., Bachmann, M., Wirth, M.P., and Rieber, E.P. (2005)
    D-TMPP: a novel androgen-regulated gene preferentially expressed in prostate and prostate cancer that is the first characterised member of an eukaryotic gene family.
    Prostate, 64, 387-400
  • Schmitz, M., Wehner, R., Stevanovic, S., Kießling, A., Rieger, M.A., Temme, A., Bachmann, M., Rieber, E.P., and Weigle, B. (2006)
    Identification of a naturally processed T cell epitope derived from the  glioma-associated protein SOX11.
    Cancer Lett. [Epub ahead of print]
  • Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Brauninger, M., Eilken, H.M., Rieger, M.A., Schroeder, T.T., Huttner, W.B., Brakebusch, C., and Gotz, M. (2006)
    The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
    Nature Neuroscience 9, 1099-107
  • Rieger M.A. and Schroeder, T. (2007)
    Hämatopoetische Stammzellen
    Review (German)
    Biospektrum, 3.2007: 254-256
  • Arakawa, H., Kudo, H., Batrak, V., Caldwell, R.B., Rieger, M.A., Ellwart, J.W. and Buerstedde, J.M. (2007)
    Protein evolution by hypermutation and selection in the B cell line DT40
    Nucleic Acids Research,     [Epub ahead of print]
  • Rieger, M.A. and Schroeder, T. (2008)
    Exploring hematopoiesis at single cell resolution.
    Cells Tissues Organs  Jan 29 [Epub ahead of print]
  • Rieger, M.A. and Schroeder, T. (2009)
    Analysing cell fate control by cytokines through continuous single cell biochemistry
    Journal of Cellular Biochemistry, 108: 343 - 352

  • Rieger, M.A., Smejkal, B.M. and Schroeder T (2009)
    Improved prospective identification of megakaryocyte-erythrocyte progenitor cells
    British Journal of Haematology, 144: 448 - 451

  • Kimura, A.*, Rieger, M.A.*, Simone, J.M., Chen, W., Wickre, M.C., Zhu, B.-M., Hoppe, P.S., O’Shea, J., Schroeder, T.** and Hennighausen, L.** (2009)
    * and ** equal contributions
    The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis
    Blood, in press

  • Rieger, M.A., Hoppe, P.S., Smejkal, B.M., Eitelhuber, A.C. and Schroeder, T. (2009)
    Hematopoietic cytokines can instruct lineage choice
    Science, 325: 217-218
    • (P)Reviews in scientific journals:
  • Rieger, M.A. and Schroeder, T. (2009)
    Instruction of lineage choice by hematopoietic cytokines
    Cell Cycle, 8: 4019 - 4020
    (PubMed)