Lung

Effective Therapies against lung diseases: Giving new breath

Joint for new approaches in therapy of chronic lung diseases

Lung diseases mean great suffering for the patients, who are greatly restricted in all areas of life by enormous difficulty in breathing. Although risk factors for lung diseases are known, it is still unclear how and why the organic changes arise and which environmental and genetic factors can promote the diseases.

Helmholtz Zentrum München investigates just these pathogenic mechanisms. The elucidation of complex interactions is crucial for the development of new therapies, diagnostic methods and prevention strategies. Alongside the new translational center for lung research (CPC, Comprehensive Pneumology Center), which was opened in a festive ceremony in the summer of 2010 by the Federal Minister of Education and Research, Prof. Dr. Annette Schavan, and the center’s proven expertise in epidemiology and pneumology, cutting-edge technology platforms are available to researchers as scientific-technical infrastructure.

Institute of Lung Biology and Disease / Comprehensive Pneumology Center (CPC)

     

  • Head: Dr. Antje Brand (acting, admin.)

  • In cooperation with LMU, the Munich University Hospital and Asklepios Pulmonary Hospital München Gauting

  • One of the aims: to study chronic lung diseases and to develop new therapies

Institutes of Epidemiology I and II, Research Unit of Molecular Epidemiology

     

  • Directors/Head: Prof. Dr. H. Schulz (acting for EPI I), Prof. Dr. Annette Peters (director of EPI II), Dr. Christian Gieger (Research Unit)

  • One of the aims: to study the incidence and pathogenesis of chronic lung diseases and the influence of individual genetic predisposition

Institute of Health Economics and Healthcare Management

     

  • Director: Prof. Dr. Reiner Leidl (Chair of Health Economics and Healthcare management at LMU)

  • One of the aims: to determine the costs of diseases, patients’ quality of life and economic feasibility of medical procedures; to define the effects of socioeconomic factors on health and healthcare – e.g. for COPD

Institute of Allergy Research

     

  • Head: Prof. Dr. Carsten Schmidt-Weber (Director, MARC Munich Allergy Research Center; Chair of Molecular Allergology at TUM)

  • One of the aims: elucidation of effect of environmental factors
    on pathogenesis, triggers and chronification of allergic reactions

Institute of Biological and Medical Imaging

     

  • Director: Prof. Dr. Vasilis Ntziachristos (Chair of Biological and Medical Imaging at TUM)

  • One of the aims: development and provision of in vivo imaging technologies

Institute of Stem Cell Research

     

  • Director: Prof. Dr. Magdalena Götz (Chair of Physiological Genomics at LMU)

  • Responsible scientist: Prof. Dr. Heiko Lickert

  • One of the aims: elucidation of the role of stem cell populations in lung diseases

 

 

Institute of Bioinformatics and Systems Biology

     

  • Director: Dr. Gabriele Kastenmüller (acting)

  • One of the aims: systems biology of chronic lung diseases

Translational Molecular Immunology

     

  • Director: Prof. Dr. Ralph Mocikat

  • One of the aims: phenotyping of immune cells in lung diseases

Cooperation Group Comprehensive Molecular Analytics (with University of Rostock)

     

  • Head: Prof. Dr. Ralf Zimmermann

  • One of the aims: Study the health impact of airborne pollutants; chemical and physical analyses of fine particles

Cooperative Health Research in the Augsburg Region (KORA)

     

  • Spokesperson: Prof. Dr. Annette Peters

  • Management: Institutes of Epidemiology and Health Economics

  • Cohort with 20,000 study participants, on the basis of regular medical examinations over the past 25 years

  • Network of epidemiological and health economics research approaches

  • One of the aims: to determine the incidence of diseases, multimorbidity, healthcare provision, environmental burdens and lifestyle factors

Aerosol Measuring Station

     

  • Head: Prof. Dr. Annette Peters

  • Comprehensive collection and characterizationof fine and ultrafine particles from ambient air

  • One of the aims: modern environmental measurements in cooperation with the University of Augsburg and the Augsburg University of Applied Sciences   

Lung Research within the Institute of Experimental Genetics

  • Director: Prof. Dr. Martin Hrabě de Angelis (Chair of Experimental Genetics at TUM)

Genome Analysis Center (GAC) and Metabolomics Platform MetaP

  • Head: Prof. Dr. Jerzy Adamski (Head of the Genome Analysis Center, Coordinator MetaP)
  • One of the aims: to study the relationships between metabolism and health risks
  • Homepage des GAC

German Mouse Clinics (GMC) and European Mouse Mutant Archive (EMMA)

  • Head: Prof. Dr. Martin Hrabě de Angelis
  • One of the aims: Development and standardized study of mouse models, archiving of mutant mouse lines   
  • Homepage der GMC