Disease and Lifestyle Biomarkers
We are searching for chemical substances that are characteristic for chronic diseases (e.g. diabetes, cardio-vascular diseases) and a certain lifestyle. Also, we are investigating in host-pathogen interactions.
So far, we could identify biomarkers for lifestyle factors such as coffee consumption, smoking or nutrition habits. Furthermore, we could identify diabetes specific metabolic pathways.
Research Highlights
- Questionnaire-based self-reported nutrition habits associate with serum metabolism as revealed by quantitative targeted metabolomics
It is unclear in how far self-reported nutrition intake reflects de facto differences in body metabolite composition. To investigate this question on an epidemiological scale we conducted a metabolomics study analyzing the association of self-reported nutrition habits with 363 metabolites quantified in blood serum of 284 male participants of the KORA population study.
Published in Eur J Epidemiol, 2010. Article
- Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting
Published in PLoS One, 2010.Article