institute of bioinformatics and systems biology / mips

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Gabi Kastenmüller

PhD


Phone: +49 (0) 89 3187 3578
Building 56
Room 151

Research Interests

  • Metabolomics
  • Associations of phenotypes, genotypes, and metabolic features
  • Large-scale comparative genome analysis on the metabolic level (mainly for microbial genomes)

Curriculum Vitae

  • 1989 - 1995 studies in chemistry at Ludwig-Maximilians-University, Munich
    Degree: master's degree in chemistry (in German: Diplom-Chemiker)
    Thesis: "Light-induced reorientation of azo dye containing, cholesteric oligosiloxanes" (in German)
  • 1993 - 1998 studies in computer science at Ludwig-Maximilians-University, Munich
    Degree: master's degree in computer science (in German: Diplom-Informatikerin)
    Thesis: "Similarity search in 3D protein databases" (in German)
  • 1999 - 2001 research assistant (part time) at Munich information center for protein sequences (MIPS), Max Planck Institute of Biochemistry, Munich
  • 2001 - 2009 research assistant at Institute of Bioinformatics and Systems Biology (IBIS), Helmholtz Zentrum München
  • 2006 - 2009 Ph.D. student at Genome-oriented Bioinformatics, Life and Food Science Center Weihenstephan, Technische Universität München
    Degree: Dr. rer. nat.
    Thesis: "In silico prediction and comparison of metabolic capabilities in sequenced genomes"
  • since Mar 2009 at Metabolomics group, IBIS, Helmholtz Zentrum München

Publications

  • Illig T, Gieger C, Zhai G, Römisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmüller G, Kato BS, Mewes HW, Meitinger T, de Angelis MH, Kronenberg F, Soranzo N, Wichmann HE, Spector TD, Adamski J, Suhre K (2010): A genome-wide perspective of genetic variation in human metabolism. Nat Genet., 42(2), pp. 137-41
  • Altmaier E, Kastenmüller G, Römisch-Margl W, Thorand B, Weinberger KM, Adamski J, IlligT, Döring A, Suhre K (2009): Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics. Mol Nutr Food Res., 53(11), pp. 1357-65.
  • Kastenmüller G, Schenk ME, Gasteiger J, Mewes HW (2009): Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. Genome Biol., 10(3), R28.
  • Walter MC, Rattei T, Arnold R, Güldener U, Münsterkötter M, Nenova K, Kastenmüller G, Tischler P, Wölling A, Volz A, Pongratz N, Jost R, Mewes HW, Frishman D (2009): PEDANT covers all complete RefSeq genomes. Nucleic Acids Res., 37(Database Issue), pp. D408-11.
  • Kastenmüller G, Gasteiger J, Mewes HW (2008): An environmental perspective on large-scale genome clustering based on metabolic capabilities. Bioinformatics, 24(16), pp. i56-62.
  • Güldener U, Münsterkötter M, Kastenmüller G, Strack N, van Helden J, Lemer C, Richelles J, Wodak SJ, Garcia-Martinez J, Perez-Ortin JE, Michael H, Kaps A, Talla E, Dujon B, Andre B (2005): CYGD: the Comprehensive Yeast Genome Database. Nucleic Acids Res, 33(Database issue), pp. D364-68.
  • Frishman D, Mokrejs M, Kosykh D, Kastenmüller G, Kolesov G, Zubrzycki I, Gruber C, Geier B, Kaps A, Albermann K, Volz A, Wagner C, Fellenberg M, Heumann K, Mewes H.-W. (2003): The PEDANT genome database. Nucleic Acids Res, 31(1), pp. 207-11.
  • Geier B, Kastenmüller G, Fellenberg M, Mewes HW, Morgenstern B (2001): The HIB database of annotated UniGene clusters. Bioinformatics, 17, pp. 571-72.
  • Ankerst M, Kastenmüller G, Kriegel HP, Seidl T (1999): Nearest Neighbor Classification in 3D Protein Databases. Proc. of the 7th Int. Conf. on Intelligent Systems for Molecular Biology (ISMB), Heidelberg, Germany. AAAI Press, pp. 34-43.
  • Ankerst M, Kastenmüller G, Kriegel HP, Seidl T (1999): 3D Shape Histograms for Similarity Search and Classification in Spatial Databases. Proc. of the 6th Int. Symposium on Spatial Databases (SSD), Hong Kong, China. Lecture Notes in Computer Science (LNCS), Vol. 1651, Springer Verlag, pp. 207-26.
  • Kastenmüller G, Kriegel HP, Seidl T (1998): Similarity Search in 3D Protein Databases. Proc. of the 6th German Conf. on Bioinformatics (GCB), Cologne, Germany.
  • Dietrich R, Kastenmüller G, Bourhill G, Bräuchle C, Leigeber HP, Weitzel HP, Kreutzer FH (1996): Generation of noncentrosymmetric structures in glassy liquid crystalline structures. Ber Bunsenges Phys Chem., 100, pp. 1128.