institute of bioinformatics and systems biology / mips

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Brigitte Wägele

PhD


Phone: +49 (0) 89 3187 3640
Building 56
Room 130a

Research Interests

  • Metabolomics of P. aeruginosa infection
  • Automated annotation of non-targeted metabolomics MS mass peaks
  • Processing and integration of biological data

Curriculum Vitae

  • 10/2000 - 09/2005: Studies of Bioinformatics at the Ludwig-Maximilians-Universität München (LMU) and the Technische Universität München (TUM)
    Diploma-Thesis: „Feature Transformationen für die Funktionsvorhersage auf Proteinen mittels Analyse der 3D Struktur“ (Feature transformations for the prediction of protein function based on 3D structure analysis).
  • 09/2005 – 03/2009: Ph.D. student at Department of Genome-oriented Bioinformatics, Life and Food Science Center Weihenstephan, Technische Universität München
    • Degree: Dr. rer. nat.
    • Thesis: „Abbildung von Transkript- und Proteinsequenzen auf genomische Referenzdaten“ (Mapping of transcript- and protein sequences on genomic reference data).
  • Since 03/2009: Member of the metabolomics group at the Institute of Bioinformatics and systems biology, Helmholtz Zentrum München and the Department of Genome-oriented Bioinformatics, Life and Food Science Center Weihenstephan, Technische Universität München funded by the ERA-NET PathoGenoMics project (Pathogen-host metabolomics and interactomics (Pathomics)).

Publications

2011

  • Suhre, K., Shin, S. Y., Petersen, A. K., Mohney, R. P., Meredith, D., Wagele, B., Altmaier, E., Deloukas, P., Erdmann, J., Grundberg, E., Hammond, C. J., de Angelis, M. H., Kastenmuller, G., Kottgen, A., Kronenberg, F., Mangino, M., Meisinger, C., Meitinger, T., Mewes, H. W., Milburn, M. V., Prehn, C., Raffler, J., Ried, J. S., Romisch-Margl, W., Samani, N. J., Small, K. S., Wichmann, H. E., Zhai, G. J., Illig, T., Spector, T. D., Adamski, J., Soranzo, N. and Gieger, C. (2011). Human metabolic individuality in biomedical and pharmaceutical research. Nature 477(7362): 54-U60.
  • Kastenmuller, G., Romisch-Margl, W., Wagele, B., Altmaier, E. and Suhre, K. (2011). metaP-Server: A Web-Based Metabolomics Data Analysis Tool. Journal of Biomedicine and Biotechnology.


2010

  • Lucio, M., Fekete, A., Weigert, C., Wagele, B., Zhao, X. J., Chen, J., Fritsche, A., Haring, H. U., Schleicher, E. D., Xu, G. W., Schmitt-Kopplin, P. and Lehmann, R. (2010). Insulin Sensitivity Is Reflected by Characteristic Metabolic Fingerprints - A Fourier Transform Mass Spectrometric Non-Targeted Metabolomics Approach. Plos One 5(10).
  • Ruepp, A., Waegele, B., Lechner, M., Brauner, B., Dunger-Kaltenbach, I., Fobo, G., Frishman, G., Montrone, C. and Mewes, H. W. (2010). CORUM: the comprehensive resource of mammalian protein complexes-2009. Nucleic Acids Research 38: D497-D501.
  • Alphonse, S., Durand, E., Douzi, B., Waegele, B., Darbon, H., Filloux, A., Voulhoux, R. and Bernard, C. (2010). Structure of the Pseudomonas aeruginosa XcpT pseudopilin, a major component of the type II secretion system. Journal of Structural Biology 169(1): 75-80.


2009

  • Waegele, B., Dunger-Kaltenbach, I., Fobo, G., Montrone, C., Mewes, H. W. and Ruepp, A. (2009). CRONOS: the cross-reference navigation server. Bioinformatics 25(1): 141-143.
  • Waegele, B., Schmidt, T., Mewes, H. W. and Ruepp, A. (2008). OREST: the online resource for EST analysis. Nucleic Acids Research 36: W140-W144.


2008

  • Ruepp, A., Brauner, B., Dunger-Kaltenbach, I., Frishman, G., Montrone, C., Stransky, M., Waegele, B., Schmidt, T., Doudieu, O. N., Mpflen, V. S. and Mewes, H. W. (2008). CORUM: the comprehensive resource of mammalian protein complexes. Nucleic Acids Research 36: D646-D650.


2007

  • Datson, N. A., Morsink, M. C., Atanasova, S., Armstrong, V. W., Zischler, H., Schlumbohm, C., Dutilh, B. E., Huynen, M. A., Waegele, B., Ruepp, A., de Kloet, E. R. and Fuchs, E. (2007). Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate. Bmc Genomics 8.