2013
- Raffler J., Römisch-Margl W., Petersen AK., Pagel P., Blochl F., Hengstenberg C., Illig T., Meisinger C., Stark K., Wichmann HE., Adamski J., Gieger C., Kastenmüller G., Suhre K. Identification and MS assisted interpretation of genetically influenced NMR signals in human plasma. Genome Med. 2013 Feb 15;5(2):13.
2012
- Altmaier E., Emeny RT., Krumsiek J., Lacruz ME., Lukaschek K., Häfner S., Kastenmüller G., Römisch-Margl W., Prehn C., Mohney RP., Evans AM., Milburn MV., Illig T., Adamski J., Theis F., Suhre K., Ladwig KH. Metabolomic profiles in individuals with negative affectivity and social inhibition: A population-based study of Type D personality. Psychoneuroendocrinology. 2012 Dec 10.
- Yu Z., Zhai G., Singmann P., He Y., Xu T., Prehn C., Römisch-Margl W., Lattka E., Gieger C., Soranzo N., Heinrich J., Standl M., Thiering E., Mittelstraß K., Wichmann HE., Peters A., Suhre K., Li Y., Adamski J., Spector TD., Illig T., Wang-Sattler R. Human serum metabolic profiles are age dependent. Aging Cell. 2012 Dec;11(6):960-7.
- Ferrannini E., Natali A., Camastra S., Nannipieri M., Mari A., Adam KP., Milburn MV., Kastenmüller G., Adamski J., Tuomi T., Lyssenko V., Groop L., Gall WE. Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance. Diabetes. 2012 Nov 16.
- Wahl S., Yu Z., Kleber M., Singmann P., Holzapfel C., He Y., Mittelstrass K., Polonikov A., Prehn C., Römisch-Margl W., Adamski J., Suhre K., Grallert H., Illig T., Wang-Sattler R., Reinehr T. Childhood obesity is associated with changes in the serum metabolite profile. Obes Facts. 2012;5(5):660-70.
- Krumsiek J., Suhre K., Evans AM., Mitchell MW., Mohney RP., Milburn MV., Wägele B., Römisch-Margl W., Illig T., Adamski J., Gieger C., Theis FJ., Kastenmüller G. Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information. PLoS Genet. 2012 Oct;8(10):e1003005.
- Wang-Sattler R., Yu Z., Herder C., Messias AC., Floegel A., He Y., Heim K., Campillos M., Holzapfel C., Thorand B., Grallert H., Xu T., Bader E., Huth C., Mittelstrass K., Döring A., Meisinger C., Gieger C., Prehn C., Römisch-Margl W., Carstensen M., Xie L., Yamanaka-Okumura H., Xing G., Ceglarek U., Thiery J., Giani G., Lickert H., Lin X., Li Y., Boeing H., Joost HG., de Angelis MH., Rathmann W., Suhre K., Prokisch H., Peters A., Meitinger T., Roden M., Wichmann HE., Pischon T., Adamski J., Illig T. Novel biomarkers for pre-diabetes identified by metabolomics. Mol Syst Biol. 2012;8:615.
- Lechner M., Höhn V., Brauner B., Dunger I., Fobo G., Frishman G., Montrone C., Kastenmüller G., Wägele B., Ruepp A. CIDeR: multifactorial interaction networks in human diseases. Genome Biol. 2012 Jul 18;13(7):R62.
- Wägele B., Witting M., Schmitt-Kopplin P., Suhre K. MassTRIX reloaded: combined analysis and visualization of transcriptome and metabolome data. PLoS One. 2012;7(7):e39860.
- Jourdan C., Petersen AK., Gieger C., Döring A., Illig T., Wang-Sattler R., Meisinger C., Peters A., Adamski J., Prehn C., Suhre K., Altmaier E., Kastenmüller G., Römisch-Margl W., Theis FJ., Krumsiek J., Wichmann HE., Linseisen J. Body fat free mass is associated with the serum metabolite profile in a population-based study. PLoS One. 2012;7(6):e40009.
- Krug S., Kastenmüller G., Stückler F., Rist M.J., Skurk T., Sailer M., Raffler J., Römisch-Margl W., Adamski J., Prehn C., Frank T., Engel K.H., Hofmann T., Luy B., Zimmermann R., Moritz F., Schmitt-Kopplin P., Krumsiek J., Kremer W., Huber F., Oeh U., Theis F.J., Szymczak W., Hauner H., Suhre K., Daniel H. The dynamic range of the human metabolome revealed by challenges. FASEB J. 2012 Jun;26(6):2607-19.
- Petersen AK., Krumsiek J., Wägele B., Theis FJ., Wichmann HE., Gieger C., Suhre K. On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies. BMC Bioinformatics. 2012 Jun 6;13:120.
- Renner S., Römisch-Margl W., Prehn C., Krebs S., Adamski J., Göke B., Blum H., Suhre K., Roscher A.A., Wolf E. Changing Metabolic Signatures of Amino Acids and Lipids During the Prediabetic Period in a Pig Model With Impaired Incretin Function and Reduced ß-Cell Mass. Diabetes. 2012 Apr 9.
- Goek O.N., Döring A., Gieger C., Heier M., Koenig W., Prehn C., Römisch-Margl W., Wang-Sattler R., Illig T., Suhre K., Sekula P., Zhai G., Adamski J., Köttgen A., Meisinger C. Serum Metabolite Concentrations and Decreased GFR in the General Population. Am J Kidney Dis. 2012 Mar 29.
- Petersen A.K., Stark K., Musameh M.D., Nelson C.P., Römisch-Margl W., Kremer W., Raffler J., Krug S., Skurk T., Rist M.J., Daniel H., Hauner H., Adamski J., Tomaszewski M., Döring A., Peters A., Wichmann H.E., Kaess B.M., Kalbitzer H.R., Huber F., Pfahlert V., Samani N.J., Kronenberg F., Dieplinger H., Illig T., Hengstenberg C., Suhre K., Gieger C., Kastenmüller G. Genetic associations with lipoprotein subfractions provide information on their biological nature. Hum Mol Genet. 2012 Mar 15;21(6):1433-43.
2011
- Suhre K., Shin SY., Petersen AK., Mohney RP., Meredith D., Wägele B., Altmaier E; CARDIoGRAM., Deloukas P., Erdmann J., Grundberg E., Hammond CJ., de Angelis MH., Kastenmüller G., Köttgen A., Kronenberg F., Mangino M., Meisinger C., Meitinger T., Mewes HW., Milburn MV., Prehn C., Raffler J., Ried JS., Römisch-Margl W., Samani NJ., Small KS., Wichmann HE., Zhai G., Illig T., Spector TD., Adamski J., Soranzo N., Gieger C., Human metabolic individuality in biomedical and pharmaceutical research. Nature, 477(7362):54-60, 2011.
- Suhre K., Wallaschofski H., Raffler J., Friedrich N., Haring R., Michael K., Wasner C., Krebs A., Kronenberg F., Chang D., Meisinger C., Wichmann H.-E., Hoffmann W., Völzke H., Völker U., Teumer A., Biffar R., Kocher T., Felix S.B., Illig T., Kroemer H.K., Gieger C., Römisch-Margl W., Nauck M., A genome-wide association study of metabolic traits in human urine Nature Genetics, 43:565-569, 2011.
Yu Z., Kastenmüller G., He Y., Belcredi P., Möller G., Prehn C., Mendes J., Wahl S., Roemisch-Margl W., Ceglarek U., Polonikov A., Dahmen N., Prokisch H., Xie L., Li Y., Wichmann H.-E., Peters A., Kronenberg F., Suhre K., Adamski J., Illig T., Wang-Sattler R., Differences between human plasma and serum metabolite profiles. PLoS One. 6(7):e21230, 2011.
- Römisch-Margl W., Prehn C., Bogumil R., Röhring C., Suhre K., Adamski J., A procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics, Metabolomics, forthcoming.
- Suhre K., Römisch-Margl W., Hrabé de Angelis M., Adamski J., Luippold G., Augustin R., Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in pre-clinical drug testing, Journal of Biomolecular Screening, Epub 4 May 2011.
- Krumsiek J., Suhre K., Illig T., Adamski J., Theis F.J., Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data, BMC Systems Biology, 5:21, 2011.
- Mewes H.W., Ruepp A., Theis F., Rattei T., Walter M., Frishman D., Suhre K., Spannagl M., Mayer K.F., Stümpflen V., Antonov A.. MIPS: curated databases and comprehensive secondary data resources in 2010, Nucleic Acids Res., 39(Database issue):D220-224, 2011.
- Kastenmüller G., Römisch-Margl W., Wägele B., Altmaier E., Suhre K., metaP-Server: a web-based metabolomics data analysis tool, J. Biomedicine & Biotechnology, pii:839862, 2011.
- Altmaier E., Kastenmüller G., Römisch-Margl W., Thorand B., Weinberger K.M., Illig T., Adamski J., Döring A., Suhre K., Questionnaire-based self-reported nutrition habits associate with serum metabolism as revealed by quantitative targeted metabolomics, European Journal of Epidemiology. 2011 Feb;26(2):145-56.
- Fuchs H., Gailus-Durner V., Adler T., Aguilar-Pimentel J.A., Becker L., Calzada-Wack J., Da Silva-Buttkus P., Neff F., Götz A., Hans W., Hölter S.M., Horsch M., Kastenmüller G., Kemter E., Lengger C., Maier H., Matloka M., Möller G., Naton B., Prehn C., Puk O., Rácz I., Rathkolb B., Römisch-Margl W., Rozman J., Wang-Sattler R., Schrewe A., Stöger C., Tost M., Adamski J., Aigner B., Beckers J., Behrendt H., Busch D.H., Esposito I., Graw J., Illig T., Ivandic B., Klingenspor M., Klopstock T., Kremmer E., Mempel M., Neschen S., Ollert M., Schulz H., Suhre K., Wolf E., Wurst W., Zimmer A., Hrabe de Angelis M., Mouse phenotyping, Methods, 2011 Feb;53(2):120-35.
- Mittelstrass K, Ried JS, Yu Z, Krumsiek J, Gieger C, Prehn C, Roemisch-Margl W, Polonikov A, Peters A, Theis FJ, Meitinger T, Kronenberg F, Weidinger S, Wichmann HE, Suhre K, Wang-Sattler R, Adamski J, Illig T. Differences between human plasma and serum metabolite profiles. PLoS Genet. 2011 Aug;7(8):e1002215.
2010
- Suhre K., Meisinger C., Döring A., Altmaier E., Belcredi P., Gieger C., Chang D., Milburn M.V., Gall W.E., Weinberger K.M., Mewes H.-W., Hrabé de AngelisM., Wichmann H.E., Kronenberg F., Adamski J., Illig T., Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting, PLoS ONE, 5:e13953, 2010.
- Weikard R., Altmaier E., Suhre K., Weinberger K.M., Hammon H.M., Albrecht E., Setoguchi K., Takasuga A., Kuehn C., Metabolomic profiles indicate distinct physiological pathways affected by two loci with major divergent effect on Bos taurus growth and lipid deposition, Physiol Genomics, 42A:79-88, 2010.
- Illig, T, Gieger, C, Zhai, G, Römisch-Margl, W, Wang-Sattler, R, Prehn, C, Altmaier, E, Kastenmüller, G, Kato, BS , Mewes, HW, Meitinger, T, Hrabé de Angelis, M, Kronenberg, F, Soranzo, N , Wichmann, HE, Spector, TD, Adamski, J, Suhre, K, A genome-wide perspective of genetic variation in human metabolism, Nature Genetics, 42:137-141, 2010, doi:10.1038/ng.507.
2009
- Altmaier, E, Kastenmüller, G, Römisch-Margl, W, Thorand, B, Weinberger, KM, Adamski, J, Illig, T, Döring, A, Suhre K, Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics, Mol. Nutr. Food Res., 53:1357-1365, 2009 [PDF].
- Sigurdardottir, AG, Arnorsdottir, A, Thorbjarnardottir, SH, Eggertsson, G, Suhre K, Kristjansson, M, Characteristics of mutants designed to incorporate a new ion pair into the structure of a cold adapted subtilisin-like serine proteinase , Biochim. Biophys. Acta 1794:512-518, 2009.
- Suhre K, Gieger C, Eine genomweite Assoziationsstudie mit Stoffwechselprodukten , BioSpektrum 03.09, 263-265, 2009.
- Walter MC, Rattei T, Arnold R, Güldener U, Münsterkötter M, Nenova K, Kastenmüller G, Tischler P, Wölling A, Volz A, Pongratz N, Jost R, Mewes HW, Frishman D. PEDANT covers all complete RefSeq genomes. Nucleic Acids Res. 2009 Jan;37(Database issue):D408-11.
- Kastenmüller G, Schenk ME, Gasteiger J, Mewes HW. Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. Genome Biol. 2009;10(3):R28.
2008
- Gieger, C, Geistlinger, L, Altmaier, E, Hrabé de Angelis, M, Kronenberg, F, Meitinger, T, Mewes, HW, Wichmann, HE, Weinberger, KM, Adamski, J, Illig, T, Suhre K, Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum , PLoS Genetics, 4(11):e1000282, 2008.
- Wang-Sattler, R, Yu, Y, Mittelstrass, K, Lattka, E, Altmaier, E, Gieger, C, Ladwig, KH, Dahmen, N, Weinberger, KM, Hao, P, Lui, L, Li, Y, Wichmann, HE, Adamski, J, Suhre K, Illig, T, Metabolic profiling reveals distinct variations linked to nicotine consumption in humans - first results from the KORA Study , PLoS One, 3(12):e3863, 2008.
- Fitzgerald LA, Boucher PT, Yanai-Balser G, Suhre K, Graves MV, and Van Etten JL, Putative gene promoter sequences in the chlorella viruses, Virology, 380:388-393, 2008.
- Altmaier E, Ramsay SL, Graber A, Mewes HW, Weinberger KM, Suhre K, Bioinformatics analysis of targeted metabolomics - uncovering old and new tales of diabetic mice under medication, Endocrinology, 149:3478-3489, 2008 [PDF].
- Suhre K and Schmitt-Kopplin P, MassTRIX: Mass TRanslator Into Pathways, Nucleic Acids Research, Volume 36, Web Server issue, W481-W484, 2008 [link to MassTRIX web-server].
- Kastenmüller G, Gasteiger J, Mewes HW. An environmental perspective on large-scale genome clustering based on metabolic capabilities. Bioinformatics. 2008 Aug 15;24(16):i56-62.