Platforms
Immunomonitoring platform
Publications
- Dembek CJ, Kutscher S, Heltai S, Allgayer S, Biswas P, Ghezzi S, Vicenzi E, Hoffmann D, Reitmeir P, Tambussi G, Bogner JR, Lusso P, Stellbrink HJ, Santagostino E, Vollbrecht T, Goebel FD, Protzer U, Draenert R, Tinelli M, Poli G, Erfle V, Malnati M, Cosma A.: Nef-specific CD45RA+ CD8+ T cells secreting MIP-1beta but not IFN-gamma are associated with nonprogressive HIV-1 infection. AIDS Res Ther. 2010 Jul 2; 7:20.
- Kutscher S, Allgayer S, Dembek CJ, Bogner JR, Protzer U, Goebel FD, Erfle V, Cosma A. MVA-nef induces HIV-1-specific polyfunctional and proliferative T-cell responses revealed by the combination of short- and long-term immune assays. . 2010 Jun 10.Gene Ther. 2010 Nov;17(11):1372-83. Epub 2010 Jun 10.
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Di Bonito P, Grasso F, Mochi S, Petrone L, Fanales-Belasio E, Mei A, Cesolini A, Laconi G, Conrad H, Bernhard H, Dembek CJ, Cosma A, Santini SM, Lapenta C, Donati S, Muratori C, Giorgi C, Federico M. Anti-tumor CD8+ T cell immunity elicited by HIV-1-based virus-like particles incorporating HPV-16 E7 protein. Virology. 2009 Dec 5;395(1):45-55. Epub 2009 Oct 2.
- Kutscher S, Dembek CJ, Allgayer S, Heltai S, Stadlbauer B, Biswas P, Nozza S, Tambussi G, Bogner JR, Stellbrink HJ, Goebel FD, Lusso P, Tinelli M, Poli G., Erfle V.,.Pohla H., Malnati.M., Cosma A;The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT. AIDS Res Ther. 2008 Oct 6;5:22."
- Mamani-Matsuda M, Cosma A, Weller S, Faili A, Staib C, Garçon L, Hermine O, Adoue D, Fieschi C, Pers JO, Arakelyan N, Varet B, Sauvanet A, Berger A, Paye F, Andrieu JM, Michel M, Godeau B, Buffet P, Reynaud CA, Weill JC:The human spleen is the main reservoir for life long memory B-cells.Blood 2008, Mar 3 [Epub ahead of print]
- Hoffmann D, Seebach J, Cosma A, Goebel FD, Strimmer K, Schätzl HM, Erfle V: Therapeutic vaccination reduces HIV sequence variability. FASEB J 2008 Jan16 [Epub ahead of print]
- Brave A, Gudmundsdotter L, Gasteiger G, Hallermalm K, Kastenmüller W, Rollman E, Boberg A, Engstrom G, Reiland S, Cosma A, Drexler I, Hinkula J, Wahren B, Erfle V: Immunization of mice with the nef gene from Human Immunodeficiency Virus type 1: Study of immunological memory and long-term toxicology. Infect Agent Cancer 2007 Jul 10; 2:14
- Cosma A, Nagaraj R, Staib C, Diemer C, Wopfner F, Schätzl H, Busch DH, Sutter G, Goebel FD, Erfle, V: Evaluation of modified vaccinia virus Ankara as an alternative vaccine against Smallpox in chronically HIV type 1-infected individuals undergoing HAART. AIDS Research and Human Retroviruses 2007, 23/6, 782-793. ultström et al. Immunol Lett. 2004
- Cosma A, Bühler S, Nagaraj R, Staib C, Hammarin AL, Wahren B, Goebel FD, Erfle V, Sutter G:> Clin Diagn Lab Immun 2004, 11/2: 406-410
- Cosma A, Nagaraj R, Bühler S, Hinkula J, Busch DH, Sutter G, Goebel FD, Erfle V: Therapeutic vaccination with MVA-HIV-1 nef elicits Nef-specific T-helper cell responses in chronically HIV-1 infected individuals. Vaccine 2003, 22: 21-29