institute of virology (viro)

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Publications 2008

  • Bernhard H, Neudorfer J, Gebhard K., Conrad H, Hermann C, Nährig J, Fend F, Weber W, Busch DH, Peschel C: Adoptive transfer of autologous, HER2-specific, cytotoxic T lymphocytes for the treatment of HER2-overexpressing breast cancer. Cancer Immunol. 2008, 57/2, 271-280.
  • Bleifuss E, Bendz H, Sirch B, Thompson S, Brandl A, Milani V, Graner MW, Drexler I, Kuppner M, Katsanis E, Noessner E, Issels RD: Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens. Int. J. Hyperthermia. 2008 Jun 20:1-15, DOI: 1080/02656
  • Bohne F, Chmielewski M, Ebert G, Wiegmann K, Kürschner T, Schulze A, Urban S, Krönke M, Abken H, Protzer U:T cells Redirected Against Hepatitis B Virus Surface Proteins Eliminate Infected Hepatocytes. Gastroenterology 2008, 134/1: 239-47.
  • Conrad H, Gebhard K, Krönig H, Neudorfer J, Busch DH, Peschel C, Bernhard H: CTLs directed against HER2 specifically cross-react with HER3 and HER4. J. Immunol. 2008. 180/ 12: 8135-8145
  • Cornberg M, Protzer U, Dollinger MM, Petersen J, Wedemeyer H, Berg T, Jilg W, Erhardt A, Wirth S, Schirmacher P, Fleig WE, Manns MP: German Society for Digestive and Metabolic Diseases; German Society for Pathology; Society for Virology; Society for Pediatric Gastroenterology and Nutrition; Competence Network for Viral Hepatitis. The German guideline for the management of hepatitis B virus infection: short version. J Viral Hepat. 2008, 15/1, 1-21.
  • Di Lullo G, Soprana E, Panigada M, Palini A, Erfle V, Staib C, Sutter G, Siccardi AG: Marker gene swapping facilitates recombinant Modified Vaccinia Virus Ankara production by host-range selection. J Virol Methods. 2008/2009 Nov 24.08. 156 (1-2): 37-43 [Epub ahead of print]
  • El-Gogo S, Flach B, Staib C, Sutter G, Adler H: In vivo attenuation of recombinant murine gammaherpesvirus 68 (MHV-68) is due to the expression and immunogenicity but not to the insertion of foreign sequences. Virology. 2008 Oct 25;380(2):322-7. Epub 2008 Sep 5. 
  • El-Gogo S, Staib C, Lasarte JJ, Sutter G, Adler H: Protective vaccination with hepatitis C virus NS3 but not vore antigen in a novel mouse challenge model. J Gene Med. 2008, 10: 177-186
  • Flockerzi A, Ruggieri A, Frank O, Sauter M, Maldener E, Kopper B, Wullich B, Seifarth W, Mueller-Lantzsch N, Leib-Mösch C, Meese E, Mayer J: Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project. BMC Genomics. 2008, 9:354, 1-17 .
  • Frank O, Verbeke C, Schwarz N, Mayer J, Fabarius A, Hehlmann R, Leib-Mösch C, Seifarth W: Variable transcriptional activity of endogenous retroviruses in human breast cancer. J. Virol. 2008, 82/4: 1808-18.
  • Frenzel LP, Abdullah Z, Kriegeskorte AK, Dieterich R, Lange N, Busch DH, Krönke M, Utermöhlen O, Hescheler J, Saric T: Role of NKG2D-ligands and ICAM-1 in NK cell-mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell-derived Cardiomyocytes. Stem Cells. 2008, doi;10 [published online]
  • Heit A, Gebhardt F, Lahl K, Neuenhahn M, Schmitz F, Anderl F, Wagner H, Sparwasser T, Busch DH, Kastenmüller K: Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity. Eur J Immunol. 2008, 38/6:1585-97.
  • Hoffmann D, Seebach J, Cosma A, Goebel FD, Strimmer K, Schätzl HM, Erfle V: Therapeutic vaccination reduces HIV sequence variability. FASEB J. 2008, 437-44.
  • Jakob T. et al. (16 Coauthors): Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis. J. Allergy Clin. 2008, 121/1; 179-184
  • Jenke AC, Wilhelm AD, Orth V, Lipps HJ, Protzer U, Wirth S: Long-term suppression of hepatitis B virus replication by short hairpin RNA expression using the scaffold/matrix attachment region-based replicating vector system pEPI-1. Antimicrob Agents Chemother. 2008,52(7):2355-9, Chapter in: Comperative Hepatitits, Urban & Protzer (eds), Birkenhäuser 2008.
  • Kraus B, Ziegler M, Wolff H: Linear fluorescence unmixing in cell biological research. Modern Research and Educational Topies in Microscopy A. Méndez-Vilas and J. Diaz (Eds.) 2007, 863-872
  • Kutscher S, Dembek CJ, Allgayer S, Heltai S, Stadlbauer B, Biswas P, Nozza S, Tambussi G, Bogner JR, Stellbrink HJ, Goebel FD, Lusso P, Tinelli M, Poli G, Erfle V, Pohla H, Malnati M, Cosma A: The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT. AIDS Res Ther. 2008 Oct 6;5:22. Doi: 10.1186/1742-6405-5-22 [PubMed - in process]
  • Lochner M, Kastenmüller K, Neuenhahn M, Weighardt H, Busch DH, Reindl, W, Förster I: Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18. Infect. Immun. 2008, 76/9: 3881-3890
  • Mamani-Matsuda M, Cosma A, Weller S, Faili A, Staib C, Garçon L, Hermine O, Beyne-Rauzy O, Fieschi C, Pers JO, Arakelyan N, Varet B, Sauvanet A, Berger A, Paye F, Andrieu JM, Michel M, Godeau B, Buffet P, Reynaud CA, Weill JC: The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells. Blood. 2008, 1;111(9):4653-9.
  • Markoullis K, Bulian D, Hölzlwimmer G, Quintanilla-Martinez L, Heiliger KJ, Zitzelsberger H, Scherb H, Mysliwietz J, Uphoff CC, Drexler HG, Adler T, Busch DH, Schmidt J, Mahabir E: Mycoplasma contamination of murine embryonic stem cells affects cell parameters, germline transmission and chimeric progeny. Transgenic Res. 2008. DOI:10.1007/s11248-008-9218 
  • Meyer VS, Kastenmüller K, Gasteiger G, Franz-Wachtel M, Lamkemeyer T, Rammensee HG, Stevanovic S, Sigurdardottir D, Drexler I: Long-term immunity against actual poxviral HLA ligands as identified by differential stable isotope labeling. J Immunol (2008) 181, 6371-6383
  • Op den Brouw ML, Binda RS, van Roosmalen MH, Protzer U, Janssen HL, van der Molen RG, Woltman AM: Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology. 2008, 28.
  • Quasdorff, M, Hösel M, Odenthal M, Zedler U, Bohne F. Gripon P, Dienes H-P, Drebber U, Stippel D, Goeser T, Protzer U: A concerted action of HNF4alpha and HNF1alpha links hepatitis B virus replication to hepatocyte differentiation. Cell Microbiol. 2008, 10(7):1478-90.
  • Rollier CS, Paranhos-Baccala G, Verschoor EJ, Verstrepen BE, Drexhage JA, Fagrouch Z, Berland JL, Komurian-Pradel F, Duverger B, Himoudi N, Staib C, Meyr M, Whelan M, Whelan JA, Adams VC, Larrea E, Riezu JI, Lasarte JJ, Bartosch B, Cosset FL, Spaan WJ, Diepolder HM, Pape GR, Sutter G, Inchauspe G, Heeney JL: Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity. Hepatology 2007,45/3: 602-613.
  • Rothenaigner I, Kramer S, Meggendorfer M, Rethwilm A, Brack-Werner R: Transduction of human neural progenitor cells with foamy virus vectors for differentiation-dependant gene expression Gene Therapy 2008, doi: 10.1038/gt
  • Sander G, Konrad A, Thurau M, Wies E, Leubert R, Kremmer E, Dinkel H, Schulz T, Neipel F, Stürzl M: Intracellular Localization Map of HHV-8 Proteins. J Virol. 2008, 82/4: 1908-22
  • Schulze K, Staib C, Schätzl HM, Ebensen T, Erfle V, Guzman CA: A prime-boost vaccination protocol optimizes immune responses against the nucleocapsid protein of the SARS coronavirus. Vaccine. 2008, 26: 6678-6684
  • Urban S, Protzer U: Hepatitis B Virus: Lessons learned from the virus life cycle. In: Weber O, Protzer U (eds). Comparative Hepatitis. Birkenhäuser 2008, 75-9