Research Unit Environmental Epidemiology
Head: Joachim Heinrich
Selected Publications / Ausgewählte Publikationen:
- Long-term Effects of Air Pollution
- Ambient and Indoor Air Pollution
- Determinants of Atopic Diseases
- Respiratory Health and Lung Function
- Chronic Bowel disease
- Further Recent Publications
Long-term Effects of Air Pollution
- Heinrich J.
Air pollution, asthma and allergies in children.
Occup Environ Med. 2010 May;67(5):290-1.
Abstract - Morgenstern V, Zutavern A, Cyrys J, Brockow I, Koletzko S, Krämer U, Behrendt H, Herbarth O, von Berg A, Bauer CP, Wichmann HE, Heinrich J; GINI Study Group; LISA Study Group.
Atopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children.
Am J Respir Crit Care Med. 2008 Jun 15;177(12):1331-7
Abstract - Slama R, Morgenstern V, Cyrys J, Zutavern A, Herbart O, Wichmann HE, Heinrich J, and the LISA study group.
Traffic-Related Atmospheric Pollutants Levels during Pregnancy and Offspring’s Term Birth Weight: a Study Relying on a Land-Use Regression Exposure Model.
Environmental Health Perspectives Sep 2007;115(9):1283-92.
Abstract - Gehring U, Heinrich J, Kramer U, Grote V, Hochadel M, Sugiri D, Kraft M, Rauchfuss K, Eberwein HG, Wichmann HE.
Long-Term Exposure to Ambient Air Pollution and Cardiopulmonary Mortality in Women.
Epidemiology 2006 Sept; 17/5:545-551.
Abstract - Brauer M, Gehring U, Brunekreef B, de Jongste J, Gerritson J, Rovers M, Wichmann HE, Wijga A, Heinrich J.
Traffic-related air pollution and otitis media.
Environmental Health Perspectives 2006; 114/9:1414-18.
Abstract - Heinrich J, Raghuyamshi VS.
Air pollution and Otitis media: A review of evidence from epidemiological studies.
Current Allergy and Asthma Reports 2004; 4: 302-309.
Abstract
- Heinrich J, Wichmann HE.
Traffic related pollutants in Europe and their effect on allergic disease.
Current Opinion in Allergy and Clinical Immunology 2004; 4:341-348.
Abstract - Heinrich J, Hoelscher B, Frye C, Meyer I, Pitz M, Cyrys J, Wjst M, Neas L, Wichmann HE.
Improved air quality in reunified Germany and decreases in respiratory symptoms.
Epidemiology 2002; 13:394-401
Abstract
Ambient and Indoor Air Pollution
- Chen CM, Tischer C, Schnappinger M, Heinrich J.
The role of cats and dogs in asthma and allergy - a systematic review.
Int J Hyg Environ Health. 2010 Jan;213(1):1-31.
Abstract - Chen CM, Rzehak P, Zutavern A, Fahlbusch B, Bischof W, Herbarth O, Borte M, Lehmann I, Behrendt H, Krämer U, Wichmann HE, Heinrich J, and the LISA Study Group.
Longitudinal Study on Cat Allergen Exposure and the Development of Allergy in Young Children.
JACI. 2007 May;119(5):1148-55.
Abstract - Heinrich J, Bedada GB, Zock JP, Chinn S, Norback D, Olivieri M, Svanes C, Ponzio M, Verlato G, Villani S, Jarvis D, Luczynska C; for the Indoor Working Group of the European Community Respiratory Health Survey II.
Cat allergen level: Its determinants and relationship to specific IgE to cat across European centers.
J Allergy Clin Immunol. 2006 Sep;118(3):674-81.
Abstract - Heinrich J, Gehring U, Cyrys J, Brauer M, Hoek G, Fischer P, Bellander T, Brunekreef B.
Exposure to traffic related air pollutants: self reported traffic intensity versus GIS modelled exposure.
Occup Environ Med 2005 Aug;62(8):517-23.
Abstract - Cyrys J, Hochadel M, Gehring U, Hoek G, Diegmann V, Brunekreef B, and Heinrich J.
GIS-Based Estimation of Exposure to Particulate Matter and NO2 in an Urban Area: Stochastic versus Dispersion Modeling.
Environmental Health Perspectives 2005; 113:987-992.
Abstract - Gehring U, Bischof W, Fahlbusch B, Wichmann HE, Heinrich J for the INGA Study Group.
House Dust Endotoxin and Allergic Sensitization in Children.
Am J Respir Crit Care Med 2002; 166: 939-944.
Abstract
Determinants of Atopic Diseases
- Berg AV, Krämer U, Link E, Bollrath C, Heinrich J, Brockow I, Koletzko S, Grübl A, Filipiak-Pittroff B, Wichmann HE, Bauer CP, Reinhardt D, Berdel D; the GINIplus study group.
Impact of early feeding on childhood eczema: development after nutritional intervention compared with the natural course - the GINIplus study up to the age of 6 years.
Clin Exp Allergy. 2010; 40:627-636.
Abstract - Chen CM, Sausenthaler S, Bischof W, Herbarth O, Borte M, Behrendt H, Krämer U, Williams HC, Wichmann HE, Heinrich J; the LISA Study Group.
Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life.
Clin Exp Dermatol. 2009 Oct 23.
Abstract - Schnabel E, Sausenthaler S, Schaaf B, Schäfer T, Lehmann I, Behrendt H, Herbarth O, Borte M, Krämer U, von Berg A, Wichmann HE, Heinrich J; LISA Study Group.
Prospective association between food sensitization and food allergy: results of the LISA birth cohort study.
Clin Exp Allergy. 2010 Mar;40(3):450-7.
Abstract - Schmitt J, Apfelbacher C, Chen CM, Romanos M, Sausenthaler S, Koletzko S, Bauer CP, Hoffmann U, Krämer U, Berdel D, von Berg A, Wichmann HE, Heinrich J, and the German Infant Nutrition Intervention plus Study Group.
Infant-onset eczema in relation to mental health problems at age 10 years: Results from a prospective birth cohort study (German Infant Nutrition Intervention plus).
The Journal of Allergy and Clinical Immunology 2010; 125(2):404-410.
Abstract - Chen CM, Weidinger S, Klopp N, Sausenthaler S, Bischof W, Herbarth O, Bauer M, Borte M, Schaaf B, Lehmann I, Behrendt H, Krämer U, Berdel D, von Berg A, Bauer CP, Koletzko S, Illig T, Wichmann HE, Heinrich J; LISA and GINI Study Group.
Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life.
Allergy. 2009 Sep;64(9):1327-32.
Abstract - Sausenthaler S, Koletzko S, Schaaf B, Lehmann I, Borte M, Herbarth O, Von Berg A, Wichmann HE, Heinrich J, for the LISA Study Group.
Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 years of age.
Am J Clin Nutr 2007 Feb;85(2):530-7.
Abstract - Sausenthaler S, Koletzko B, Heinrich J.
Dietary fat intake and allergic diseases.
Curr Nutr Food Science 2006; 2:351-359.
(Abstract not available) - Filipiak B, Zutavern A, Koletzko S, von Berg A, Brockow I, Grubl A, Berdel D, Reinhardt D, Bauer CP, Wichmann HE, Heinrich J, GINI-Group.
Solid food introduction in relation to eczema: results from a four-year prospective birth cohort study.
J Pediatr. 2007 Oct;151(4):352-8
Abstract - Zutavern A, Brockow I, Schaaf B, Bolte G, von Berg A, Diez U, Borte M, Herbarth O, Wichmann HE, Heinrich J, LISA Study Group.
Timing of Solid Food Introduction in Relation to Atopic Dermatitis and Atopic Sensitization: Results from a Prospective Birth Cohort Study.
Pediatrics 2006; 117/2:401-411.
Abstract - Heinrich J, Mielck A, Schafer I, Mey W.
Social inequality and environmentally-related diseases in Germany: review of empirical results.
Soz Praventivmed 2000;45(3):106-18.
Abstract
- Kohlhammer Y, Heinrich J.
Chlorine, chlorination by-products and their allergic and respiratory health effects.
Current Respiratory Medicine Reviews 2007; 3:39-47.
Respiratory Health and Lung Function
- Schnabel E, Chen CM, Koch B, Karrasch S, Jorres RA, Schafer T, Vogelmeier C, Ewert R, Schaper C, Volzke H, Obst A, Felix SB, Wichmann HE, Glaser S, Heinrich J, Cooperative Research In The Region Of Augsburg Study Group K.
Regional differences in prediction models of lung function in Germany.
Respir Res. 2010 Apr 22;11(1):40.
Abstract - Götschi T, Heinrich J, Sunyer J, Künzli N.
Long-term effects of ambient air pollution on lung function: a review.
Epidemiology 2008 Sep;19(5):690-701.
Abstract - Chinn S, Jarvis D, Melotti R, Luczynska C, Ackermann-Liebrich U, Anto JM, Cerveri I, de Marco R, Gislason T, Heinrich J, Janson C, Kunzli N, Leynaert B, Neukirch F, Schouten J, Sunyer J, Svanes C, Vermeire P, Wjst M, Burney P.
Smoking cessation, lung function, and weight gain: a follow-up study.
Lancet 2005 May;365(9471):1629-35; discussion 1600-1.
Abstract
Chronic Bowel disease
- Timmer A, Kemptner D, Takses A, Klebl F, Jöckel KH.
A survey based index was validated for measuring disease activity in inflammatory bowel disease. An evaluation study.
J Clin Epidemiol. 2009 Jul;62(7):771-8
Abstract - Ott C, Obermeier F, Thieler S, Kemptner D, Bauer A, Schölmerich J, Rogler G, Timmer A.
The incidence of inflammatory bowel disease in a rural region of Southern Germany – a prospective population based study.
Eur J Gastroenterol Hepatol 2008; 20(9):917-23
Abstract - Timmer A, Obermeier F.
Reduced risk of ulcerative colitis after appendicectomy (editorial).
Br Med J 2009; 338:b225. - Timmer A, Kemptner D, Bauer A, Takses A, Ott C, Fürst A.
Determinants of female sexual function in inflammatory bowel disease - A survey based cross sectional analysis.
BMC Gastroenterol, 2008:8:45.
Abstract
Further recent publications
- Lattka E, Illig T, Koletzko B, Heinrich J.
Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism.
Curr Opin Lipidol. 2010; 21:64-69.
Abstract - Stiegler P, Sausenthaler S, Buyken AE, Rzehak P, Czech D, Linseisen J, Kroke A, Gedrich K, Robertson C, Heinrich J.
A new FFQ designed to measure the intake of fatty acids and antioxidants in children.
Public Health Nutr 2010; 13:38-46.
Abstract - Rückinger S, Rzehak P, Chen CM, Sausenthaler S, Koletzko S, Bauer CP, Hoffmann U, Kramer U, Berdel D, von Berg A, Bayer O, Wichmann HE, von Kries R, Heinrich J.
Prenatal and Postnatal Tobacco Exposure and Behavioral Problems in 10-Year-Old Children: Results from the GINI-plus Prospective Birth Cohort Study.
Environ Health Perspect. 2010 Jan;118(1):150-4.
Abstract - Rzehak P, Scherag A, Grallert H, Sausenthaler S, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Borte M, Herbarth O, Krämer U, Illig T, Wichmann HE, Hebebrand J and J Heinrich for the GINI and LISA Study Group.
Associations between BMI with the FTO gene age dependent. Results from the GINI and LISA birth cohort studies up to age 6 years.
Obesity Facts 2010 (in press). - Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Chen CM, Tiesler C, Heinrich J, Boomsma DI, Smith GD, Power C, Jaddoe VWV, Jarvelin M, McCarthy MI for the Early Growth Genetics (EGG) Consortium.
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
Nat Genet. 2010 May;42(5):430-5. Epub 2010 Apr 6.
Abstract - Rzehak P, Heinrich J, Klopp N, Schaeffer L, Hoff S, Wolfram G, Illig T, Linseisen J. Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes.
Br J Nutr. 2009 Jan;101(1):20-6.
Abstract - Rzehak P, Sausenthaler S, Koletzko S, Reinhardt D, von Berg A, Krämer U, Berdel D, Bollrath C, Grübl A, Bauer CP, Wichmann HE, Heinrich J for the German Infant Nutritional Intervention Study. Short- and long-term effects of feeding hydrolyzed protein infant formulas on growth at ≤ 6 y of age: results from the German Infant Nutritional Intervention Study.
Am J Clin Nutr. 2009; 89:1846-56.
Abstract