Basis
Projects:
- Effects of nutrition on metabolism
- Role of mitochondria in the pathogenesis and disease course of diabetes
- Relationships between arteriosclerosis, liver, kidney, thyroid gland and diabetes development
- Genetische Determination verschiedener Subtypen von Diabetes
- Genetic determination of different subtypes of diabetes
- Association between diabetes risk and gender
- Central nervous control of systems metabolism
Successes:
- Elucidation of the functions of genes
- Relationship of smoking and diabetes
- Relationship of birth weight and diabetes
- Genetic causes identified for disturbances in the lipid metabolism
New Approaches to Therapy
Projects:
- Specific nutritional forms for diabetes intervention
- Possibilities of regeneration of beta cells and approaches to stem cell therapy
- Vaccination study for type 1 diabetes
- Polypharmacy for treatment of diabetes and obesity
Successes:
- Immunotherapy for type 1 diabetes
New Diagnostic Methods
Projects:
- Measurement of risk factors for diabetes in the exhaled air
- Early diagnosis through metabolites in the blood
Successes:
- New markers for early detection of type 1 diabetes mellitus
New Prevention Strategies
Projects:
- Influence of lifestyle factors such as nutrition, exercise etc. on the course of disease
- Nutritional intervention in carriers of risk gene variants
- Changes in gene expression depending on diabetes status and genetic profile
Successes:
- Genetic risk factors identified for type 1 and type 2 diabetes
- Vitamin D may reduce diabetes risk
Health Care Research
Projects:
- Benefit analysis of disease management programs
- Diabetes and social imbalances
- Influence of mental state/depression on the course of disease
Successes:
- Benefit of disease management programs is confirmed