Study management and recruitment (ongoing)
Study objective:
Complex diseases are caused by environmental and genetic factors. Their prevalence is rising world wide causing a high burden for many societies and are thus of high socioeconomic relevance. Recruitment of patients suffering from complex diseases is frequently multi-centered including different medical institutions and researchers of different fields (geneticists, epidemiologists, statisticians, medical doctors).
Specific aims:
With our clinical partners we conduct:
- Field work-logistics
- Modelling work flow between the partners and continuous quality control.
- Development of questionnaires and study material.
- Training of staff
- Recruiting of study population
- Investigation of addresses and telephone numbers
- Recruitment of index patients and family members.
- Interviews (face to face, by telephone)
- Coordination of specimen collection through hospitals and general practitioners
- Data management
- Real time study management and document tracking.
- Documentation of data and specimen entry
- Integration of phenotypic and genotypic data
- Plausibility checks, data cleaning and quality control
- Database development (MS Access, Ingres))
- Status reports and descriptive analyses (SAS)
Current studies and projects:
- LUCY (Lung Cancer in the Young) – field study
- LUCY Flyer [Link: AG BIOGEN: PDF_LUCY_Flyer]
- AFNET-A4 – field study (detailed project description)
- Biomarkers of radiation susceptibility – field study (Start 2008)
- ILCCO – Project (detailed project description)
Investigators:
Gabi Wölke, Wiebke Sauter, Thomas Illig, Christian Gieger, H.-Erich Wichmann.
Internal Participants:
H.-Erich Wichmann (principle investigator), Thomas Illig (principle investigator), Gabi Wölke (coordinator, recruitment), Wiebke Sauter (coordinator, biobanking, genetic analysis), Christian Gieger (coordinator, databases) Claudia Hanrieder (recruitment), Angelika Steinwachs (coordinator, data management) Birgit Langer (data management).
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