The Research Unit

To complement clinical and basic research units, the Research Unit Analytical Pathology at the Helmholtz Zentrum München scientifically develops translational research on diseases that manifest in tissues.

For example, the Research Unit Analytical Pathology explores the translation of in-vitro models or animal models into applications for humans. These could be laboratory methods that open up new avenues for diagnosis or attempts to explain why a certain disease develops under certain conditions. The primary research objectives are the search for diagnostic/theragnostic biomarkers and new target structures for treatment, as well as histopharmacological analysis of active substances in healthy, predisposed or diseased tissues in a future personalized medication.

The Research Unit Analytical Pathology links basic research and diagnostic application, and translates the findings from experimental and molecular pathology into procedures for disease classification and predictive diagnostics on tissue.

Microscopic imaging methods are key technologies for the molecular analysis of healthy, predisposed and pathologically altered tissues and cells. The Research Unit Analytical Pathology focuses its cutting edge infrastructure and expertise in order to research diseases that manifest in tissues. All current platform technologies combine microscopic imaging methods with the analysis of individual molecules or complex molecular signatures. The starting point is always the classic morphological evaluation of the tissues and cells to be analyzed, a step that is necessary for an exact categorization of molecular alterations at the level of individual cells or cell organelles.

  • Application and development of microscopic imaging for combined morphological and molecular analysis of tissues and cells
  • Development of imaging methods for active agent analysis in tissues
  • Image analysis platform for microscope image data

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