Open science

CLUE: Multiplexed sgRNA library design and production

Pooled sgRNA libraries targeting hundreds or thousands of individual genes are right at the heart of functional genomics. Such libraries are broadly available, but usually not tailored to the scientific interest of researchers. With our tool CRISPR clue were were out to bring custom sgRNA library production to all labs - streamlining the cloning process, lowering synthesis costs and reducing bioinformatics to the bare minimum. Check out and the manuscript preprint available at!