Publications

2018

2017

2016

2015

2014

2013

2012

2011

2010

Bergboer, J.G.M., Zeeuwen, P.L.J.M., Irvine, A.D., Weidinger, S., Giardina, E., Novelli, G., Den Heijer, M., Rodriguez, E., Illig, T., Riveira-Munoz, E., Campbell, L.E., Tyson, J., Dannhauser, E.N., O´Regan, G., Galli, E., Klopp, N., Koppelman, G.H., Novak, N., Estivill, X., McLean, W.H.I., Postma, D.S., Armour, J.A.L., Schalwijk, J. et al.: Deletion of Late Cornified Envelope 3B and 3C Genes Is Not Associated with Atopic Dermatitis. J Invest Dermat 130, 2057-2061 (2010)

Burbulla, L.F., Schelling, C., Kato, H., Rapaport, D., Woitalla, D., Schiesling, C., Schulte, C., Sharma, M., Illig, T., Bauer, P., Jung, S., Nordheim, A., Schöls, L., Riess, O., Krüger, R.: Dissecting the role of the mitochondrial chaperone mortalin in Parkinson`s disease: functional impact of disease-related variants on mitochondrial homeostasis. Hum Mol Genet 19(22), 4437-4452 (2010)

Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A.U., Wheeler, E., Glazer, N.L., Bouatia-Naji, N., Grallert, H., Gieger, C., Meisinger, C., Wichmann, H.E., Illig, T., Barroso, I. for the MAGIC investigators et al.: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics 42(2), 105-116 (2010)

Elks, C.E., Perry, J.R.B., Sulem, P., Chasman, D.I., Franceschini, N., He, C., Lunetta, K.L., Visser, J.A., Byrne, E.M., Cousminer, D.L., Gudbjartson, D.F., Esko, T., Feenstra, B., Hottenga, J.J., Albrecht, E., Döring, A., Illig, T., Wichmann, H.E. et al.: Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 42(12), 1077-1085 (2010)

Frank, B., Hoffmeister, M., Klopp, N., Illig, T., Chang-Claude, J., Brenner, H.: Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1, and BLM. Carcinogenesis 31(3), 442-445 (2010)

Frank, B., Hoffmeister, M., Klopp, N., Illig, T., Chang-Claude, J., Brenner, H.: Single nucleotide polymorphisms in Wnt signalling and cell death pathway genes and susceptibility to colorectal cancer. Carcinogenesis 31(8), 1381-1386 (2010)

Grallert, H., Herder, C., Marzi, C., Meisinger, C., Wichmann, H.E., Rathmann, W., Illig, T.: Association of Genetic Variation in KCNQ1 with Type 2 Diabetes in the KORA Surveys. Horm Metab Research 42, 149-151 (2010)

Hemminki, K., Müller-Myhsok, B., Engel, C., Chen, B., Lichtner, P., Burwinkel, B., Sutter, C., Wappenschmidt, B., Hellebrand, H., Illig, T., Arnold, N., Niederacher, D., Dworniczak, B., Deissler, H., Kast, K., Gadzicki, D., Meitinger, T., Wichmann, H.E., Kiechle, M., Bartram, C.R., Schmutzler, R.K., Meindl, A.: Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients. Int J Cancer 126, 2858-2862 (2010)

Holzapfel, C., Grallert, H., Huth, C., Wahl, S., Fischer, B., Döring, A., Rückert, I.M., Hinney, A., Hebebrand, J., Wichmann, H.E., Hauner, H., Illig, T., Heid, I.M.: Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA. Int J Obes (Lond) 34(10), 1538-1545 (2010)

Horn, D., Kapeller, J., Rivera-Brugués, N., Moog, U., Lorenz-Dpiereux, B., Eck, S., Hempel, M., Wagenstaller, J., Gawthrope, A., Monaco, A.P., Bonin, M., Riess, O., Wohlleber, E., Illig, T., Bezzina, C.R., Franke, A., Spranger, S., Villavicencio-Lorini, P., Seifert, W., Rosenfeld, J., Klopocki, E., Rappold, G.A., Strom, T.M.: Identification of FOXP1 Deletions in Three Unrelated Patients with Mental Retardation and Significant Speech and Language Deficits. Human Mutation: Mutation in Brief 31, E1851-E1860 (2010)

Illig, T., Gieger, C., Zhai, G., Römisch-Margl, W., Wang-Sattler, R., Prehn, C., Altmaier, E., Kastenmüller, G., Kato, B.S., Soranzo, N., Mewes, H.W., Meitinger, T., Hrabé de Angelis, M., Kronenberg, F., Wichmann, H.E., Spector, T.D., Adamski, J., Suhre, K.: A genome-wide perspective of genetic variation in human metabolism. Nat Genet 42(2), 137-141 (2010)

Lattka, E., Eggers, S., Moeller, G., Heim, K., Weber, M., Mehta, D., Prokisch, H., Illig, T., Adamski, J.: A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1. J Lipid Res 51, 182-191 (2010)

Lattka, E., Illig, T., Heinrich, J., Koletzko, B.: Do FADS genotypes enhance our knowledge about fatty acid related phenotypes? Clin Nutr 29, 277-287 (2010)

Lubitz, S., Schober, W., Pusch, G., Effner, R., Klopp, N., Behrendt, H., Buters, J.T.M.: Polycyclic Aromatic Hydrocarbons from Diesel Emissions Exert Proallergic Effects in Birch Pollen Allergic Individuals Through Enhanced Mediator Release from Basophils. Environ Toxicol 25, 188-197 (2010)

Mahachie John, J.M., Baurecht, H., Rodriguez, E., Naumann, A., Wagenpfeil, S., Klopp, N., Mempel, M., Novak, N., Bieber, T., Wichmann, H.E., Ring, J., Illig, T., Cattaert, T., Van Stehen, K., Weidinger, S.: Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on total IgE levels and eczema risk. Allergy 65, 875-882 (2010)

Marzi, C., Albrecht, E., Hysi, P., Lagou, V., Waldenberger, M., Tönjes, A., Prokopenko, I., Heim, K., Blackburn, H., Ried, J.S., Kleber, M.E., Mangino, M., Thorand, B., Peters, A., Grallert, H., Geistlinger, L., Wichmann, H.E., Illig, T., Gieger, C. et al.: Genome-Wide Association Study Identifies Two Novel Regions at 11p15.5-p13 and 1p31 with Major Impact on Acute-Phase Serum Amyloid A. PLoS Genetics 6(11):e1001213, 1-8 (2010)

Michel, S., Liang, L., Depner, M., Klopp, N., Ruether, A., Kumar, A., Schedel, M., Vogelberg, C., von Mutius, E., von Berg, A., Bufe, A., Rietschel, E., Heinzmann, A., Laub, O., Simma, B., Frischer, T., Genuneit, J., Gut, I.G., Schreiber, S., Lathrop, M., Illig, T., Kabesch, M.: Unifying candidate gene and GWAS Approaches in Asthma. PLoS ONE 5(11):e13894, 1-10 (2010)

Mobascher, A., Rujescu, D., Mittelstraß, K., Giegling, I., Lamina, C., Nitz, B., Brenner, H., Fehr, C., Breitling, L.P., Gallinat, J., Rothenbacher, D., Raum, E., Müller, H., Ruppert, A., Hartmann, A.M., Möller, H.J., Gieger, C., Wichmann, H.E., Illig, T., Winterer, G. et al.: Association of a Variant in the Muscarinic Acetylcholine Receptor 2 Gene (CHRM2) With Nicotine Addiction. Am J Med Genet Part B 153B, 684-690 (2010)

Müller, T.D., Brönner, G., Wandolski, M., Carrie, J., Nguyen, T.T., Greene, B.H., Scherag, A., Grallert, H., Vogel, C.I.G., Scherag, S., Rief, W., Wichmann, H.E., Illig, T., Schaefer, H., Hebebrand, J., Hinney, A.*: Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity. BMC Med Genet 11:2, 1-9 (2010)

Neuschl, C., Hantschel, C., Wagener, A., Schmitt, A.O., Illig, T., Brockmann, G.A.: A unique genetic defect on chromosome 3 is responsible for juvenile obesity in the Berlin Fat Mouse. Int J Obesity 34, 1706-1714 (2010)

Perry, J.R.B., Weedon, M.N., Langenberg, C., Jackson, A.U., Lyssenko, V., Sparso, T., Thorleifsson, G., Grallert, H., Ferrucci, L., Maggio, M., Paolisso, G., Walker, M., Palmer, C.N.A., Payne, F., Young, E., Herder, C., Narisu, N., Morken, M.A., Bonnycastle, L.L., Owen, K.R., Shields, B., Knight, B., Illig, T., McCarthy, M.I., Frayling, T.M. et al.: Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 19(3), 535-544 (2010)

Pinto, L.A., Depner, M., Klopp, N., Illig, T., Vogelberg, C., von Mutius, E., Kabesch, M.: MMP-9 gene variants increase the risk for non-atopic asthma in children. Respiratory Research 11:23, 1-9 (2010)

Rabstein, S., Brüning, T., Harth, V., Fischer, H.P., Haas, S., Weiss, T., Spickenheuer, A., Pierl, C., Justenhoven, C., Illig, T., Vollmert, C., Baisch, C., Ko, Y.D., Hamann, U., Brauch, H., Pesch, B., for the GENICA Network: N-acetyltransferase 2, exposure to aromatic and heterocyclic amines, and receptor-defined breast cancer. Eur J Cancer Prev 19, 100-109 (2010)

Santhiya, S.T., Kumar, G.S., Sudhakar, P., Gupta, N., Klopp, N., Illig, T., Söker, T., Groth, M., Platzer, M., Gopinath, P.M., Graw, J.: Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms. Mol Vision 16, 1837-1847 (2010)

Sauber, J., Grothe, J., Behm, M., Scherag, A., Grallert, H, Illig, T., Hinney, A., Hebebrand, J., Wiegand, S., Grüters, A., Krude, H., Biebermann, H.: Association of variants in the glucose dependent insulinotropic peptide receptor gene (GIPR) with impaired glucose homeostasis in obese children and adolescents from Berlin. Eur J Endocrinol 163, 259-264 (2010)

Saxena, R., Hivert, M.F., Langenberg, C., Tanaka, T., Pankow, J.S., Vollenweider, P., Lyssenko, V., Bouatia-Naji, N., Dupuis, J., Jackson, A.U., Kao, W.H.L., Li, M., Glazer, N.L., Manning, A.K., Luan, J., Stringham, H.M., Prokopenko, I., Johnson, T., Grarup, N., Boesgaard, T.W., Lecoeur, C., Grallert, H., Illig, T., Wichmann, H.E., Watanabe, R.M. for the MAGIC investigators et al.: Genetic variation in GIPR influneces the glucose and insulin responses to an oral glucose challenge. Nature Genetics 42(2), 142-148 (2010)

Scherag, A., Dina, C., Hinney, A., Vatin, V., Scherag, S., Vogel, C.I.G., Müller, T.D., Grallert, H., Wichmann, H.E., Balkau, B., Heude, B., Jarvelin, R., Hartikainen, A.L., Levy-Marchal, C., Weill, J., Delplanque, J., Körner, A., Kiess, W., Kovacs, P., Heinrich, J., Rzehak, P., Illig, T., Meyre, D. et al.: Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genetics 6(4):e1000916, 1-10 (2010)

Schmid, E., Roos, H., Sauter, W., Rickinger, A., Jaehnert, I., Eckardt-Schupp, F.: Chromosome analysis of the differential radiosensitivity of an Epstein-Barr virus (EBV)-transformed B cell line and B and T lymphocytes from the same blood donor. Int J Radiat Biol 86(1), 47-55 (2010)

Speliotes, E.K., Willer, C.J., Berndt, S.I., Monda, K.L., Thorleifsson, G., Jackson, A.U., Lango Allen, H., Lindgren, C., Luan, J., Mägi, R., Randall, J.C., Vedantam, S., Winkler, T.W., Qi, L., Heid, I.M., Rzehak, P., Heinrich, J., Illig, T., Peters, A., Wichmann, H.E., Loos, R.J.F. et al.: Association analyses of 249, 796 individuals reveal 18 new loci associated with body mass index. Nat Genet 42(11), 937-948 (2010)

Stark, K., Esslinger, U.B., Reinhard, W., Petrov, G., Winkler, T., Komajda, M., Isnard, R., Charron, P., Villard, E., Cambien, F., Tiret, L., Aumont, M.C., Dubourg, O., Trochu, J.N., Baumert, J., Illig, T., Klopp, N., Wichmann, H.E., Meisinger, C., Heid, I., Hengstenberg, C. et al.: Genetic Association Study Identifies HSPB7 as a Risk Gene for Idiopathic Dilated Cardiomyopathy. PLoS Genetics 6(10), 1-9 (2010)

Suttner, K., Depner, M., Wetzke, M., Klopp, N., von Mutius, E., Illig, T.: Genetic variants harbored in the forkhead box protein 3 locus increase hay fever risk To the Editor. J Allergy Clin Immunol 125(6), 1395-1399 (2010)

Tan, S., Scherag, A., Janssen, O.E., Hahn, S., Lahner, H., Dietz, T., Scherag, S., Grallert, H., Ganz Vogel, C.I., Kimmig, R., Illig, T., Mann, K., Hebebrand, J., Hinney, A.*: Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS). BMC Med Genet 11:12, 1-9 (2010)

Teupser, D., Baber, R., Ceglarek, U., Scholz, M., Illig, T., Gieger, C., Holdt, L.M., Leichtle, A., Greiser, K.H., Huster, D., Linsel-Nitschke, P., Schäfer, A., Braund, P.S., Tiret, L., Stark, K., Raaz-Schrauder, D., Heid, I.M., Wichmann, H.E., Thiery, J. et al.: Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease. Circ Cardiovasc Genet 3, 331-339 (2010)

Timofeeva, M., Kropp, S., Sauter, W., Beckmann, L., Rosenberger, A., Illig, T., Jäger, B., Mittelstrass, K., Dienemann, H., The LUCY-Concortium, Bartsch, H., Bickeböller, H., Chang-Claude, J., Risch, A., Wichmann, H.E.: Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer. Int J Cancer 127, 1547-1561 (2010)

Triglyceride Coronary Disease Genetics and Emerging Risk Factors Collaboration, with Sarwar, N., Danesh, J., Butterworth, A.S., Di Angelantonia, E., Grallert, H., Illig, T., Danesh, J. et al.: Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet 375, 1634-1639 (2010)

Truong, T., Hung, R.J., Amos, C.I., Wu, X., Bickeböller, H., Rosenberger, A., Sauter, W., Illig, T., Wichmann, H.E., Risch, A., Dienemann, H., Kaaks, R., Yang, P., Jiang, R., Wiencke, J.K., Spix, M.R. et al.: Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: a Pooled Analysis From the International Lung Cancer Consortium. J Nat Cancer Institute 102, 959-971 (2010)

Truong, T., Sauter, W., McKay, J.D., Hosgood, D., Gallagher, C., Amos, C., Spitz, M., Muscat, J., Lazarus, P., Illig, T., Wichmann, H.E., Bickeböller, H., Risch, A., Dienemann, H., Zhang, Z.F, Hung, R.J. et al.: International Lung Cancer Consortium: Coordinated association study of 10 potential lung cancer susceptibility variants. Carcinogenesis 31(4), 625-633 (2010)

Winkler, C., Bonifacio, E., Grallert, H., Henneberger, L., Illig, T., Ziegler, A.G.: BMI at age of 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKALI. Diabetes 59, 2063-2067 (2010)

Zhai, G., Wang-Sattler, R., Hart, D.J., Arden, N.K., Hakim, A.J., Illig, T., Spector, T.D.: Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis. Ann Rheum Dis 69, 1227-1231 (2010)

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before 2010

2009


Achenbach, P., Lampasona, V., Landherr, U., Koczwara, M., Krause, S., Grallert, H., Winkler, C., Pflüger, M., Illig, T., Bonifacio, E., Ziegler, A.G.: Autoantibodies to zinc transporter 8 and SLC20A8 genotype stratify type 1 diabetes risk. Diabetologia 52, 1881-1888 (2009)

Blandin, S.A., Wang-Sattler, R., Lamacchia, M., Gagneur, J., Lycett, G., Ning, Y., Levashina, E.A., Steinmetz, L.M.: Dissecting the Genetic Basis of Resistance to Malaria Parasites in Anopheles gambiae. Science 326, 147-150 (2009)

Böhme, M., Grallert, H., Klapper, M., Gieger, C., Fischer, A., Heid, I., Wichmann, H.E., Döring, F., Illig, T.: Association between functional FAB2 promoter haplotypes and body mass index: Analyses of 8072 participants of the KORA cohort study. Mol Nutr Food Res 53, 681-685 (2009)

Breitling, L.P., Dahmen, N., Illig, T., Rujescu, D., Nitz, B., Raum, E., Winterer, G., Rothenbacher, D., Brenner, H.: Variants in COMT and spontaneous smoking cessation: retrospective cohort analysis of 925 cessation events. Pharmacogenetics and Genomics 19, 657-659 (2009)

Breitling, L.P., Dahmen, N., Mittelstraß, K., Illig, T., Rujescu, D., Raum, E., Winterer, G., Brenner, H.: Smoking Cessation and Variations in Nicotinic Acetylcholine Receptor Subunits a-5, a-3, and ß-4 Genes. Biol Psychiatr 65, 691-695 (2009)

Brown, J., Donev, A., Aslanidis, C., Bracegirdle, P., Dixon, K., Foedinger, M., Gwilliam, R., Hardy, M., Illig, T., Ke, X., Krinka, D., Lagerberg, C., Laiho, P., Lewis, D.H., McArdle, W., Patton, S., Ring, S.M., Schmitz, G., Stevens, H., Tybring, G., Wichmann, H.E., Ollier, W.E.R., Yuille, M.: Observational study on variability between biobanks in the estimation of DNA concentration. BMC Res Notes 2:208, 1-8 (2009)

Cameron, L., Depner, M., Kormann, M., Klopp, N., Illig, T., von Mutius, E., Kabesch, M.: Genetic variation in CRTh2 influences development of allergic phenotypes. Allergy 64, 1478-1485 (2009)

Eberlein, A., Takasuga, A., Setoguchi, K., Pfuhl, R., Flisikowski, K., Fries, R., Klopp, N., Fürbass, R., Weikard, R., Kühn, C.*: Dissection of Genetic Factors Modulating Fetal Growth in Cattle Indicates a Substantial Role of the Non-SMC Condensin I Complex, Subunit G (NCAPG) Gene. Genetics 183, 951-964 (2009)

Eggers, S.: Analysis of DNA-binding proteins within the FADS2 gene promoter region. Masterarbeit, 1-170 (2009)

Ekelund, E., Bradley, M., Weidinger, S., Jovanovic, D.L., Johansson, C., Lindgren, C.M., Todorova, A., Jakob, T., Illig, T., von Mutius, E., Braun-Fahrländer, C., Doekes, G., Riedler, J., Scheynius, A., Pershagen, G., Kockum, I., Kere, J.: Lack of Association between Neuropeptide S Receptor 1 Gene (NPSR1) and Eczema in Five European Populations. Acta Derm Venerol 89, 115-121 (2009)

Esparza-Gordillo, J., Weidinger, S., Fölster-Holst, R., Bauerfeind, A., Ruschendorf, F., Patone, G., Rohde, K., Marenholz, I., Schulz, F., Kerscher, T., Hubner, N., Wahn, U., Schreiber, S., Franke, A., Vogler, R., Heath, S., Baurecht, H., Novak, N., Rodriguez, E., Illig, T., Lee-Kirsch, M.A., Ciechanowicz, A., Kurek, M., Piskackova, T., Macek, M., Lee, Y.A., Ruether, A.: A common variant on chromosome 11q13 is associated with atopic dermatitis. Nat Genet 41(5), 596-601 (2009)

Fernández-Santiago, R., Hoenig, S., Lichtner, P., Sperfeld, A.D., Sharma, M., Berg, D., Weichenrieder, O., Illig, T., Eger, K., Meyer, T., Anneser, J., Münch, C., Zierz, S., Gasser, T., Ludolph, A.: Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis. J Neurol 256, 1337-1342 (2009)

Fischer, A., Grallert, H., Böhme, M., Gieger, C., Boomgaarden, I., Heid, I., Wichmann, H.E., Döring, F., Illig, T.: Association Analysis Between the Prostaglandin E Synthase 2 R298H Polymorphism and Body Mass Index in 8079 Partisipants of the KORA Study Cohort. Genetic Testing and Molecular Biomarkers 13(2), 223-226 (2009)

Fuchs, J., Mueller, J.C., Lichtner, P., Schulte, C., Munz, M., Berg, D., Wüllner, U., Illig, T., Sharma, M., Gasser, T.: The transcription factor PITX3 is associated with sporadic Parkinson`s disease. Neurobiol Aging 30, 731-738 (2009)

Graw, J., Schmidt, W., Minogue, P.J., Rodriguez, J., Tong, J.J., Klopp, N., Illig, T., Ebihara, L., Barthoud, V.M., Beyer, E.C.: The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation. Mol Vision 15, 1881-1885 (2009)

Greve, B., Dreffke, K., Rickinger, A., Könemann, S., Fritz, E., Eckardt-Schupp, F., Amler, S., Sauerland, C., Braselmann, H., Sauter, W., Illig, T., Schmezer, P., Gomolka, M., Willich, N., Bölling, T.: Multicentric investigation of ionising radiation-induced cell death as a predictive parameter of individual radiosensitivity. Apoptosis 14, 226-235 (2009)

Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M., Pahwa, J.S., Maskvina, V., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Lovestone, S., Powell, J., Proitsi, P., Lupton, M.K., Brayne, C., Rubinsztein, D.C., Gill, M., Lawlor, B., Klopp, N., Wichmann, H.E., Williams, J. et al.: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer`s disease. Nat Genet 41(10), 1088-1093 (2009)

Herder, C., Rathmann, W., Strassburger, K., Finner, H., Grallert, H., Huth, C., Meisinger, C., Gieger, C., Martin, S., Giani, G., Scherbaum, W.A., Wichmann, H.E., Illig, T.: Variants of the PPARG, IGF2BP2, CDKAL1, HHEX and TCF7L2 Genes Confer Risk of Type 2 Diabetes Independently of BMI in the German KORA Studies. Horm Metab Res 40, 722-726 (2008)

Hersberger, M., Müller, M., Marti-Jaun, J., Heid, I.M., Coassin, S., Young, T.F., Waechter, V., Hengstenberg, C., Meisinger, C., Peters, A., König, W., Holmer, S., Schunkert, H., Klopp, N., Kronenberg, F., Illig, T.: No association of two functional polymorphisms in human ALOX15 with myocardial infarction. Atherosclerosis 205, 192-196 (2009)

Justenhoven, C., Pierl, C.B., Haas, S., Fischer, H.P., Hamann, U., Baisch, C., Harth, V., Spickenheuer, A., Rabstein, S., Vollmert, C., Illig, T., Pesch, B., Brüning, T., Dippon, J., Ko, Y.D., Brauch, H.: Polymorphic loci of E2F2, CCND1 and CCND3 are associated with HER2 status of breast tumors. Int J Cancer 124, 2077-2081 (2009)

Kolz, M., Baumert, J., Gohlke, H., Grallert, H., Döring, A., Peters, A., Wichmann, H.E., Koenig, W., Illig, T.: Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: Results from the MONICA/KORA study. Thromb Haemost 101, 317-324 (2009)

Kormann, M.S.D., Ferstl, R., Depner, M., Klopp, N., Spiller, S., Illig, T., Vogelberg, C., von Mutius, E., Kirschning, C.J., Kabesch, M.: Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk. Allergy 64, 636-642 (2009)

Kretzschmar, H., Illig, T.: Are further genetic factors associated with the risk of developing variant Creutzfeldt-Jakob disease? Lancet Neurol 8, 25-26 (2009)

Landi, M.T., Chatterjee, N., Yu, K., Goldinn, L.R., Goldstein, A.M., Rotunno, M., Mirabello, L., Jacobs, K., Wheeler, W., Yeager, M., Bergen, A.W., Li, Q., Consonni, D., Pesatori, A.C., Wacholder, S., Thun, M., Diver, R., Oken, M., Virtamo, J., Albanes, D., Wang, Z., Burdette, L., Sauter, W., Wichmann, H.E., Caporaso, N.E. et al.: A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromsome 5p15 Associated with Risk for Adenocarcinoma. Am J Hum Genet 85, 1-13 (2009)

Lattka, E., Illig, T., Heinrich, J., Koletzko, B.: FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases. J Nutrigenet Nutrigenomics 2, 119-128 (2009)

Nitz, B., Heim, R., Schneppat, U.E., Hyman, I., Haszprunar, G.: Towards a new standard in slug species descriptions: The case of LIMAX SARNENSIS HEIM & NITZ N.Sp. (Pulmonata: Limacidae) from the western central alps. J Molluscan Stud 75, 279-294 (2009)

Pinto, L.A., Depner, M., Steudemann, L., Klopp, N., Illig, T., von Mutius, E., Kabesch, M.: IL15 gene variants are not associated with asthma and atopy. Allergy 64, 643-646 (2009)

Prokopenko, I., Langenberg, C., Florez, J.C., Saxena, R., Soranzo, N., Thorleifson, G., Loos, R.J., Manning, A.K., Jackson, A.U., Aulchenko, Y., Potter, S.C., Erdos, M.R., Sanna, S., Hottenga, J.J., Wheeler, E., Kaakinen, M., Lyssenko, V., Chen, W.M., Ahmadi, K., Beckmann, J.S., Illig, T., Wichmann, H.E., et al.: Variants in MTNR1B influence fasting glucose levels. Nat Genet 41(1), 77-81 (2009)

Rodriguez, E., Baurecht, H., Herberich, E., Wagenpfeil, S., Brown, S.J., Cordell, H.J., Irvine, A.D., Weidinger, S.: Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease. J Allergy Clin Immunol 123, 1361-1370 (2009)

Salanti, G., Southam, L., Altshuler, D., Ardlie, K., Barroso, I., Boejnke, M., Cornelis, M.C., Frayling, T.M., Grallert, H., Grarup, N., Groop, L., Hansen, T., Hattersley, A.T., Hu, F.B., Hveem, K., Illig, T., Kuusisto, J., Laakso, M., Langenberg, C., Lyssenko, V., McCarthy, M.I., Morris, A., Morris, A.D., Palmer, C.N.A., Ioannidis, J.P.A. et al.: Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations. Am J Epidemiol 170(5), 537-545 (2009)

Schlachter, K., Gruber-Sedlmayr, U., Stogmann, E., Lausecker, M., Hotzy, C., Balzar, J., Schuh, E., Baumgartner, C., Mueller, J.C., Illig, T., Wichmann, H.E., Lichtner, P., Meitinger, T., Strom, T.M., Zimprich, A., Zimprich, F.: A splice site variant in the sodium channel gene SCN1A confers risk of febrile seizures. Neurology 72, 974-978 (2009)

Scholz, S.W., Houlden, H., Schulte, C., Sharma, M., Li, A., Berg, D., Melchers, A., Segarane, B., Gibbs, R., Simon-Sanchez, J., Paisan-Ruiz, C., Bras, J., Ding, J., Chen, H., Traynor, B.J., Arepalli, S., Zonozi, R.R., Revesz, T., Holton, J., Oertel, W., Wuellner, U., Goldwurm, S., Illig, T., Gasser, T. et al.: SNCA Variants Are Associated with Increased Risk for Multiple System Atrophy. Ann Neurol 65, 610-614 (2009)

Sharma, M., Lichtner, P., Kruger, R., Berg, D., Schulte, C., Illig, T., Riess, O., Gasser, T.: Further delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson`s disease. Neurobiology Aging 30, 1706-1709 (2009)

Simón-Sánchez, J., Schulte, C., Bras, J.M., Sharma, M., Gibbs, J.R., Berg, D., Paisan-Ruiz, C., Lichtner, P., Scholz, S.W., Hernandez, D.G., Krüger, R., Federoff, M., Klein, C., Goate, A., Perlmutter, J., Bonin, M., Nalls, M.A., Illig, T., Gieger, C., Houlden, H., Steffens, M., Okun, M.S., Racette, B.A., Singleton, A.B., Gasser, T. et al.: Genome-wide association study reveals genetic risk underlying Parkinson`s disease. Nat Genet 41(12), 1308-1312 (2009)

Singmann, P., Baumert, J., Herder, C., Meisinger, C., Holzapfel, C., Klopp, N., Wichmann, H.E., Klingenspor, M., Rathmann, W., The KORA group, Illig, T., Grallert, H.: Gene-Gene Interaction between APOA5 and USF1: Two Candidate Genes for the Metabolic Syndrome. Obes Facts 2, 235-242 (2009)

Stark, K., Reinhard, W., Grassl, M., Erdmann, J., Schunkert, H., Illig, T., Hengstenberg, C.: Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease. PLoS one 4(11), 1-7 (2009)

Suttner, K., Depner, K., Klopp, N., Illig, T., Vogelberg, C., Adamski, J., von Mutius, E., Kabesch, M.: Genetic variants in the GATA3 gene are not associated with asthma and atopic diseases in German children. J Allergy Clin Immunol 123(5), 1179-1181 (2009)

Suttner, K., Rosenstiel, P., Depner, M., Schedel, M., Pinto, L.A., Ruether, A., Adamski, J., Klopp, N., Illig, T., Vogelberg, C., Schreiber, S., von Mutius, E., Kabesch, M.: TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. J Allergy Clin Immunol 123, 1062-1068 (2009)

Suttner, K., Ruoss, I., Rosenstiel, P., Depner, M., Pinto, L.A., Schedel, M., Adamski, J., Illig, T., Schreiber, S., von Mutius, E., Kabesch, M.: HLX1 gene variants influence the development of childhood asthma. J Allergy Clin Immunol 123, 82-88 (2009)

Timofeeva, M., Jäger, B., Rosenberger, A., Sauter, W., Wichmann, H.E., KORA Study Group, Bickeböller, H., Risch, A.: A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers. Clin Biochemistry 42, 500-509 (2009)

Timofeeva, M., Kropp, S., Sauter, W., Beckmann, L., Rosenberger, A., Illig, T., Jäger, B., Mittelstrass, K., Dienemann, H., The LUCY-Consortium, Bartsch, H., Bickeböller, H., Chang-Claude, J., Risch, A., Wichmann, H.E.: CYP 450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences. Carcinogenesis 30(7), 1161-1169 (2009)

Vogel, C.I.G., Greene, B., Scherag, A., Müller, T.D., Friedel, S., Grallert, H., Heid, I.M., Illig, T., Wichmann, H.E., Schäfer, H., Hebebrand, J., Hinney, A.: Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry. BMC Med Genet 10:14, 1-6 (2009)

Vogel, I.G., Scherag, A., Brönner, G., Nguyen, T.T., Wang, H.J., Grallert, H., Bornhorst, A., Rosskopf, D., Völzke, H., Reinehr, T., Rief, W., Illig, T., Wichmann, H.E., Schäfer, H., Hebebrand, J., Hinney, A.: Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups. BMC Med Genet 10:19, 1-10 (2009)

Winkler, C., Illig, T., Koczwara, K., Bonifacio, E., Ziegler, A.G.: HHEX-IDE Polymorphism Is Associated with Low Birth Weight in Offspring with a Family History of Type 1 Diabetes. J Clin Endocrin Metab 94(10), 4113-4115 (2009)

Zeilinger, S., Pinto, L.A., Nockher, W.A., Depner, M., Klopp, N., Illig, T., von Mutius, E., Renz, H., Kabesch, M.: The effect of BDNF gene variants on asthma in German children. Allergy 64, 1790-1794 (2009)


2008


Gohlke, H., Ferrari, U., Koczwara, K., Bonifacio, E., Illig, T., Ziegler, A.: SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset. Rev Diabet Stud 5, 25-27 (2008)
Herder, C., Illig, T., Baumert, J., Müller, M., Klopp, N., Khuseyinova, N., Meisinger, C., Poschen, U., Martin, S., Koenig, W., Thorand, B.: RANTES/CCL 5 gene polymorphisms, serum concentrations, and incident type 2 diabetes. results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Eur J Endocrinol 158, R1-R5 (2008)

Herder, C., Illig, T., Baumert, J., Müller, M., Klopp, N., Khuseyinova, N., Meisinger, C., Martin, S., Thorand, B., Koenig, W.: Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: Results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Atherosclerosis 200, 380-388 (2008)

Herder, C., Klopp, N., Baumert, J., Müller, M., Khuseyinova, N., Meisinger, C., Martin, S., Illig, T., Koenig, W., Thorand, B.: Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case-Cohort Study, 1984-2002. Diabetologia 51, 276-284 (2008)

Holzapfel, C., Baumert, J., Grallert, H., Müller, A.M., Thorand, B., Khuseyinova, N., Herder, C., Meisinger, C., Hauner, H., Wichmann, H.E., Koenig, W., Illig, T., Klopp, N.: Genetic variants in the USF1 gene are associated withlow-density lipoprotein cholesterol levels and incident type 2 diabetes mellitus in women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Eur J Endocrinol 159, 407-416 (2008)

Huth, C.: IL6 Gene Promoter Polymorphisms, Type 2 Diabetes Mellitus, and Related Quantitive Traits: Joint Analysis of Individual Participants´ Data from 18 International Studies. Regensburg: Roderer Verlag, 133 S. (2008)

Justenhoven, C., Hamann, U., Schubert, F., Zapatka, M., Pierl, C.B., Rabstein, S., Selinski, S., Mueller, T., Ickstadt, K., Gilbert, M., Ko, Y.D., Baisch, C., Pesch, B., Harth, V., Bolt, H.M., Vollmert, C., Illig, T., Eils, R., Dippon, J., Brauch, H.: Breast cancer: a candidate gene approach across the estrogen metabolic pathway. Breast Cancer Res Treat108, 137-149 (2008)

Justenhoven, C., Pierl, C.B., Haas, S., Fischer, H.P., Baisch, C., Hamann, U., Harth, V., Pesch, B., Brüning, T., Vollmert, C., Illig, T., Dippon, J., Ko, Y.D., Brauch, H.: The CYP1B1_1358_GG genotype is associated with estrogen receptor-negative breast cancer. Breast Cancer Res Treat 111, 171-177 (2008)

Kolz, M., Baumert, J., Müller, M., Khuseyinova, N., Klopp, N., Thorand, B., Meisinger, C., Herder, C., Koenig, W., Illig, T.: Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol. BMC Medical Genetics 9(1): 9 (2008)

Kormann, M.S., Depner, M., Hartl, D., Klopp, N., Illig, T., Adamski, J., Vogelberg, C., Weiland, S.K., von Mutius, E., Kabesch, M.: Toll-like receptor heterodimer variants protect from childhood asthma. J Allergy Clin Immunol 122(1), 86-92(+92e1-e8) (2008)

Lücking, C.B., Lichtner, P., Dichgans, M., Illig, T., Gieger, C., Berg, D., Gasser, T.: Polymorphisms in the proteasomal subunit alpha4 are not associated with Parkinson`s disease. J Neurol 255, 441-442 (2008)

Malerba, G., Schaeffer, L., Xumerle, L., Klopp, N., Trabetti, E., Biscuola, M., Cavallari, U., Galavotti, R., Martinelli, N., Guarini, P., Girelli, D., Olivieri, O., Corrocher, R., Heinrich, J., Pignatti, P. F., Illig, T.: SNPs of the FADS Gene Cluster are Associated with Polyunsaturated Fatty Acids in a Cohort of Patients with Cardiovascular Disease. Lipids 43, 289-299 (2008)

Martinelli, N., Girelli, D., Malerba, G., Guarini, P., Illig, T., Trabetti, E., Sandri, M., Friso, S., Pizzolo, F., Schaeffer, L., Heinrich, J., Pignatti, P.F., Corrocher, R., Olivieri, O.: FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. Am J Clin Nutr 88(4), 941-949 (2008)

Mittelstrass, K., Sauter, W., Rosenberger, A., Illig, T., Timofeeva, M., Klopp, N., Dienemann, H., Meese, E., Sybrecht, G., Wölke, G., Cebulla, M., Degen, M., Morr, H., Drings, P., Gröschel, A., grosse Kreymborg, K., Häußinger, K., Höffken, G., Schmidt, C., Jilge, B., Schmidt, W., Ko, Y.D., Täuscher, D., Chang-Claude, J., Wichmann, H.E., Bickeböller, H., Risch, A.: Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene. BMC Cancer 8:113, 1-9 (2008)

Novak, N., Baurecht, H., Schäfer, T., Rodriguez, E., Wagenpfeil, S., Klopp, N., Heinrich, J., Behrendt, H., Ring, J., Wichmann, E., Illig, T., Weidinger, S.: Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel. J Invest Dermatology 128, 1430-1435 (2008)

Rabstein, S., Unfried, K., Ranft, U., Illig, T., Kolz, M., Mambetova, C., Vlad, M., Roman, C., Weiss, T., Becker, D., Brüning, T., Pesch, B.: Lack of Association of Delta-Aminolevulinate Dehydratase Polymorphisms with Blood Lead Levels and Hemoglobin in Romanian Women from a Lead-Contaminated Region. J Toxicology Environ Healt Part A 71, 716-724 (2008)

Rodriguez, E., Illig, T., Weidinger, S.: Filaggrin loss-of-function mutations and association with allergic diseases. Pharmacogenomics 9(4), 399-413 (2008)

Roeber, S., Grasbon-Frodl, E.M., Windl, O., Krebs, B., Xiang, W., Vollmert, C., Illig, T., Schröter, A., Arzberger, T., Weber, P., Zerr, I., Kretzschmar, H.A.: Evidence for a Pathogenic Role of Different Mutations at Codon 188 of PRNP. PLoS ONE 3(5), 1-8 (2008)

Rosenberger, A., Illig, T., Korb, K., Klopp, N., Zietemann, V., Wölke, G., Meese, E., Sybrecht, G., Kronenberg, F., Cebulla, M., Degen, M., Drings, P., Groeschel, A., Konietzko, N., grosse Kreymborg, K., Häußinger, K., Höffken, G., Jilge, B., Ko, Y.D., Morr, H., Schmidt, C., Täuscher, D., Bickeböller, H., Wichmann, H.E.: Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years. BMC Cancer 8:60, 1-12 (2008)

Sauter, W., Rosenberger, A., Beckmann, L., Kropp, S., Mittelstrass, K., Timofeeva, M., Wölke, G., Steinwachs, A., Scheiner, D., Meese, E., Sybrecht, G., Kronenberg, F., Dienemann, H., Chang-Claude, Dienemann, H., The LUCY-Consortium, Chang-Claude, J., Illig, T., Wichmann, H.E., Bickeböller, H., Risch, A.: Matrix Metallproteinase-1 (MMP1) Is Associated with Early-Onset Lung Cancer. Cancer Epidemiol Biomarkers Prev 17(5), 1127-1135 (2008)

Schedel, M., Pinto, L.A., Schaub, B., Rosenstiel, P., Cherkasov, D., Cameron, L., Klopp, N., Illig, T., Vogelberg, C., Weiland, S.K., von Mutius, E., Lohoff, M., Kabesch, M.: IRF-1 Gene Variations Influence IgE Regulation and Atopy. Am J Respir Crit Care Med 177, 613-621 (2008)

Schmidt, W., Klopp, N., Illig, T., Graw, J.: A novel GJA8 mutation causing a recessive triangular cataract. Mol Vis 14, 851-856 (2008)

Schneider, J., Illig, T., Rosenberger, A., Bickeböller, H., Wichmann, H.E.: Detection of ATM Gene Mutations in Young Lung Cancer Patients: A Population-based Control Study. Arch Med Res 39, 226-231 (2008)

Wang-Sattler, R., Yu, Y., Mittelstrass, K., Lattka, E., Altmaier, E., Gieger, C., Ladwig, K.H., Dahmen, N., Weinberger, K.M., Hao, P., Liu, L., Li, Y., Wichmann, H.E., Adamski, J., Suhre, K., Illig, T.: Metabolic Profiling Reveals Distinct Variations Linked to Nicotine Consumption in Humans – First Results from the KORA Study. PLoS one 3(12): e3863, 1-10 (2008)

Weidinger, S., Baurecht, H., Wagenpfeil, S., Henderson, J., Novak, N., Sandilands, A., Chen, H., Rodriguez, E., O´Regan, G.M., Watson, R., Liao, H., Zhao, Y., Barker, J.N.W.N., Allen, M., Reynolds, N., Meggitt, S., Northstone, K., Smith, G.D., Strobl, C., Stahl, C., Kneib, T., Klopp, N., Bieber, T., Behrendt, H., Palmer, C.N.A., Wichmann, H.E., Ring, J., Illig, T., McLean, W.H.I., Irvine, A.D.: Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk. J Allergy Clin Immunol 122(3), 560-568 (2008)

Weidinger, S., Gieger, C., Rodriguez, E., Baurecht, H., Mempel, M., Klopp, N., Gohlke, N., Wagenpfeil, S., Ollert, M., Ring, J., Behrendt, H., Heinrich, J., Novak, N., Bieber, T., Krämer, U., Berdel, D., von Berg, A., Bazer, C.P., Herbarth, O., Koletzko, S., Prokisch, H., Mehta, D., Meitinger, T., Depner, M., von Mutius, E., Liang, L., Moffatt, M., Cookson, W., Kabesch, M., Wichmann, H.E., Illig, T.: Gernome-Wide Scan on Total Serum IgE Identifies FCER1A as Novel Susceptibility Locus. PLoS Genetics 4(8), 1-9 (2008)

Weidinger, S., O´Sullivan, M., Illig, T., Baurecht, H., Depner, M., Rodriguez, E., Ruether, A., Klopp, N., Vogelberg, C., Weiland, S.K., McLean, W.H.I., von Mutius, E., Irvine, A.D., Kabesch, M.: Filaggrin mutations, atopic eczema, hay fever, and asthma in children. J Allergy Clin Immunol 121, 1203-1209 (2008)

Zeggini, E., Scott, L.J., Saxena, R., Voight, B.F., for the DIAGRAM Consortium with, Grallert, H., Illig, T.: Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics 40(5), 638-645 (2008)


2007


Abou Jamra, R., Becker, T., Klopp, N., Dahdouh, F., Schulze, T.G., Gross, M., Deschner, M., Schmäl, C., Illig, T.*, Rietschel, M., Propping, P., Cichon, S., Nöthen, M.M., Schumacher, J.: No evidence for an association between variants at the ?-amino-n-butyric acid type A receptor ß2 locus and schizophrenia. Psychiatr Genet 17, 43-45 (2007)

Baurecht, H., Irvine, A.D., Novak, N., Illig, T., Bühler, B., Ring, J., Wagenpfeil, S., Weidinger, S.: Toward a major risk factor for atopic eczema: Meta-analysis of filaggrin polymorphism data. J Allergy Clin Immunol 120, 1406-1412 (2007)

Boulesteix, A.L., Strobl, C., Weidinger, S., Wichmann, H.E., Wagenpfeil, S.: Multiple Testing for SNP-SNP Interactions. Statistical Applications in Genetics and Molecular Biology 6(1), Article 37 (2007)

Depner, M., Kormann, M.S.D., Klopp, N., Illig, T., Vogelberg, C., Weiland, S.K., von Mutius, E., Combadière, C., Kabesch, M.: CX3CR1 Polymorphisms Are Associated with Atopy but Not Asthma in German Children. Int Arch Allergy Immunol 144, 91-94 (2007)

Fisher, E., Nitz, I., Gieger, C., Grallert, H., Gohlke, H., Lindner, I., Dahm, S., Boeing, H., Burwinkel, B., Rathmann, W., Wichmann, H.E., Schrezenmeir, J., Illig, T., Döring, F.: Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations. Mol Nutr Food Res 51, 178-184 (2007)

Georgi, A., Jamra, R.A., Klein, K., Wolf Villela, A., Schumacher, J., Becker, T., Paul, T., Schmael, C., Höfels, S., Klopp, N., Illig, T., Propping, P., Cichon, S., Nöthen, M.M., Schulze, T.G., Rietschel, M.: Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample. Psychiatr Genet 17, 308-310 (2007)

Gohlke, H.: Genetische Assoziation von SNPs aus PPARD mit BMI in der KORA S4 Studie. Magisterarbeit, 53 S. (2006)  

Hinney, A., Nguyen, T.T., Scherag, A., Friedel, S., Brönner, G., Müller, T.D., Grallert, H., Illig, T., Wichmann, H.E., Rief, W., Schäfer, H., Hebebrand, J.: Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants. PLoS ONE 12, e1361: 1-5 (2007)

Hoffmann, K., Mattheisen, M., Dahm, S., Nürnberg, P., Roe, C., Johnson, J., Cox, N.J., Wichmann, H.E., Wienker, T.F., Schulze, J., Schwarz, P.E., Lindner, T.H.: A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2. Diabetologia 50, 1418-1422 (2007)

Holzapfel, C., Klopp, N., Grallert, H., Huth, C., Gieger, C., Meisinger, C., Strassburger, K., Giani, G., Wichmann, H.E., Laumen, H., Hauner, H., Herder, C., Rathmann, W., Illig, T.: Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study). Eur J Endocrinol 157, R1-R5 (2007)

Jaremko, M., Justenhoven, C., Schroth, W., Abraham, B.K., Fritz, P., Vollmert, C., Illig, T., Simon, W., Schwab, M., Brauch, H.: Polymorphism of the DNA repair enzyme XRCC1 is associated with treatment prediction in anthracycline and cyclophosphamide/methotrexate/5-fluorouracil-based chemotherapy of patients with primary invasive breast cancer. Pharmacogenet Genomics 17, 529-538 (2007)  

Kabesch, M., Depner, M., Dahmen, I., Weiland, S.K., Vogelberg, C., Niggemann, B., Lau, S., Illig, T., Klopp, N., Wahn. U., Reinhardt, D., von Mutius, E., Nickel, R.: Polymorphisms in eosinophil pathway genes, asthma and atopy. Allergy 62, 423-428 (2007)

Kamm, C., Asmus, F., Mueller, J., Mayer, P., Sharma, M., Muller, U.S., Beckert, S., Ehling, R., Illig, T., Wichmann, H.E., Poewe, W., Mueller, J.C., Gasser, T.: Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia. Neurology 67, 1857-1859 (2006)

Krämer, U., Illig, T., Grune, T., Krutmann, J., Esser, C.: Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype. Genes and Immunity 8, 513-517 (2007)

Marzi, C., Huth, C., Kolz, M., Grallert, H., Meisinger, C., Wichmann, H.E., Rathmann, W., Herder, C., Illig, T.: Variants of the Transcription Factor 7-Like 2 Gene (TCF7L2) are Strongly Associated with Type 2 Diabetes but not with the Metabolic Syndrome in the MONICA/KORA Surveys. Horm Metab Res 39, 46-52 (2007)

Moffatt, M.F., Kabesch, M., Liang, L., Dixon, A.L., Strachan, D., Heath, S., Depner, M., von Berg, A., Bufe, A., Rietschel, E., Heinzmann, A., Simma, B., Frischer, T., Willis-Owen, S.A.G., Wong, K.C.C., Illig, T., Vogelberg, C., Weiland, S.K., von Mutius, E., Abecasis, G.R., Farrall, M., Gut, I.G., Lathrop, G.M., Cookson, W.O.C.: Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448, 470-474 (2007)

Mueller, J.C., Riemenschneider, M., Schoepfer-Wendels, A., Gohlke, H., Konta, L., Friedrich, P., Illig, T., Laws, S.M., Förstl, H., Kurz, A.: Weak independent association signals between IDE polymorphisms, Alzheimer`s disease and cognitive measures. Neurobiol Aging 28, 727-734 (2007)

Nitz, I., Fisher, E., Grallert, H., Li, Y., Gieger, C., Rubin, D., Boeing, H., Spranger, J., Lindner, I., Schreiber, S., Rathmann, W., Gohlke, H., Döring, A., Wichmann, H.E., Schrezenmeir, J., Döring, F., Illig, T.: Association of Prostaglandin E Synthase 2 (PTGES2) Arg298His Polymorphism with Type 2 Diabetes in two German Study Populations. J Clin Endocrin Metab 92(8), 3183-3188 (2007)

Novak, N., Yu, C.F., Bussmann, C., Maintz, L., Peng, W.M., Hart, J., Hagemann, T., Diaz-Lacava, A., Baurecht, H.J., Klopp, N., Wagenpfeil, S., Behrendt, H., Bieber, T., Ring, J., Illig, T., Weidinger, S.: Putative association of a TRR9 promoter polymorphism with atopic eczema. Allergy 62, 766-772 (2007)

Pauli, S., Söker, T., Klopp, N., Illig, T., Engel, W., Graw, J.: Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene. Mol Vis 13, 962-967 (2007)

Pinto, L.A., Steudemann, L., Depner, M., Klopp, N., Illig, T., Weiland, S.K., von Mutius, E., Kabesch, M.: STAT1 gene variations, IgE regulation and atopy. Allergy 62, 1456-1461 (2007)

Rokavec, M., Justenhoven, C., Schroth, W., Istrate, M.A., Haas, S., Fischer, H.P., Vollmert, C., Illig, T., Hamann, U., Ko, Y.D., Glavac, D., Brauch, H.: A Novel Polymorphism in the Promoter Region of ERBB4 Is Associated with Breast and Colorectal Cancer Risk. Clin Cancer Res 13(24), 7506-7514 (2007)

Schirmbeck, F., Georgi, A., Strohmaier, J., Schmael, C., Knorr, C., Abou Jamra, R., Schumacher, J., Becker, T., Klopp, N., Illig, T., Wulf, M., Schwarz, M., Maier, W., Propping, P., Cichon, S., Nöthen, M.M., Schulze, T.G., Rietschel, M.: No association between the serine racemase gene (SRR) and bipolar disorder in a German case-control sample. Psychiatr Genet 17, 127 (2007)

Sedlacek, K., Neureuther, K., Mueller, J.C., Stark, K., Fischer, M., Baessler, A., Reinhard, W., Broeckel, U., Lieb, W., Erdmann, J., Schunkert, H., Riegger, G., Illig, T., Meitinger, T., Hengstenberg, C.: Lymphotoxin-a and galectin-2 SNPs are not associated with myocardial infarction in two different German populations. J Mol Med 85, 997-1004 (2007)

Sedlmeier, E.M., Grallert, H., Huth, C., Löwel, H., Herder, C., Strassburger, K., Giani, G., Wichmann, H.E., Hauner, H., Illig, T., Rathmann, T.: Gene variants of monocyte chemoattractant protein 1 and components of metabolic syndrome in KORA S4, Augsburg. Eur J Endocrinol 156, 377-385 (2007)

Skowronek, M.H., Georgi, A., Jamra, R.A., Schumacher, J., Becker, T., Schmael, C., Paul, T., Deschner, M., Höfels, S., Wulff, M., Schwarz, M., Klopp, N., Illig, T., Propping, P., Cichon, S., Nöthen, M.M., Schulze, T.G., Rietschel, M.: No association between genetic variants at the ASCT1 gene and schizophrenia or bipolar disorder in a German sample. Psychiat Genet 16, 233-234 (2006)

Strohmaier, J., Georgi, A., Schirmbeck, F., Schmael, C., Abou Jamra, R., Schumacher, J., Becker, T., Höfels, S., Klopp, N., Illig, T., Propping, P., Cichon, S., Nöthen, M.M., Rietschel, M., Schulze, T.G.: No association between the serine racemase gene (SRR) and schizophrenia in a German case-control sample. Psychiatric Genetics 17, 125 (2007)

Terhorst, D., Kalali, B.N., Weidinger, S., Illig, T., Novak, N., Ring, J., Ollert, M., Mempel, M.: Monocyte-derived dendritic cells from highly atopic individuals are not impaired in their pro-inflammatory response to toll-like receptor ligands. Clin Exp Allergy 37, 381-390 (2007)

Vollmert, C., Hahn, S., Lamina, C., Huth, C., Kolz, M., Schöpfer-Wendels, A., Mann, K., Bongardt, F., Mueller, J.C., Kronenberg, F., Wichmann, H.E., Herder, C., Holle, R., Löwel, H., Illig, T., Janssen, O.E., and the KORA group: Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians. Am J Physiol Endocrinol Metab 292, E836-E844 (2007)

Weidinger, S., Rodriguez, E., Stahl, C., Wagenpfeil, S., Klopp, N., Illig, T., Novak, N.: Filaggrin Mutations Strongly Predispose to Early-Onset and Extrinsic Atopic Dermatitis. J Invest Dermatology 127, 724-726 (2007)


2006


Abou Jamra, R., Klein, K., Wolf Villela, A., Becker, T., Schulze, T.G., Schmael, C., Deschner, M., Klopp, N., Illig, T., Propping, P., Cichon, S., Rietschel, M., Nöthen, M.M., Schumacher, J.: Association Study Between Genetic Variants at the PIP5K2A Gene Locus and Schizophrenia and Bipolar Affective Disorder. Am J Med Genet Part B (Neuropsychiat Genet) 141B, 663-665 (2006)

Arking, D.E., Pfeufer, A., Post, W., Kao, W.H.L., Newton-Cheh, C., Ikeda, M., West, K., Kashuk, C., Akyol, M., Perz, S., Jalilzadeh, S., Illig, T., Gieger, C., Guo, C.Y., Larson, M.G., Wichmann, H.E., Marbán, E., O'Donnell, C.J., Hirschhorn, J.N., Kääb, S., Spooner, P.M., Meitinger, T., Chakravarti, A.: A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nature Genetics 38(6), 644-651 (2006)

Baghai, T.C., Binder, E.B., Schule, C., Salyakina, D., Eser, D., Lucae, S., Zwanzger, P., Haberger, C., Zill, P., Ising, M., Deiml, T., Uhr, M., Illig, T., Wichmann, H.E., Modell, S., Nothdurfter, C. Holsboer, F., Müller-Myhsok, B., Möller, H.J., Rupprecht, R., Bondy, B.: Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. Mol Psychiatr 11, 1003-1015 (2006)

Cullmann, M.: Assoziationen von USF1-Gen-Varianten mit Parametern des Metabolischen Syndroms und Diabetes Mellitus Typ 2 in der populationsbasierten KORA-Studie. Bachelorarbeit, 80 S. (2006)

Fernández-Santiago, R., Sharma, M., Mueller, J.C., Gohlke, H., Illig, T., Anneser, J., Münch, C., Ludolph, A., Kamm, C., Gasser, T.: Possible gender-dependant association of vascular endothelial growth factor (VEGF) gene and ALS. Neurology 66, 1929-1931 (2006)

Georgi, A., Jamra, R.A., Schumacher, J., Becker, T., Schmael, C., Deschner, M., Höfels, S., Wulff, M., Schwarz, M., Klopp, N., Illig, T., Propping, P., Cichon, S., Nöthen, M.M., Rietschel, M. and Schulze, T.G.: No association between genetic variants at the GRIN1 gene and bipolar disorder in a German sample. Psychiatr Genet 16, 183-184 (2006)

Gohlke, H., Illig, T., Klopp, N., Wagenpfeil, S., Konta, L., Laws, S.M., Kurz, A., Riemenschneider, M.: Association study between the D10S1423 microsatellite marker and Alzheimer`s disease. Neurobiology of Aging 27, 776.e1-776.e3 (2006)

Grallert, H., Huth, C., Kolz, M., Meisinger, C., Herder, C., Strassburger, K., Giani, G., Wichmann, H.E., Adamski, J., Illig, T., Rathmann, W.: IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4. Experimental Gerontology 41, 737-745 (2006)

Graw, J., Klopp, N., Illig, T., Preising, M.N., Lorenz, B.: Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P. Graefe's Arch Clin Exp Ophtalmol 244, 912-919 (2006)

Herder, C., Müller-Scholze, S., Rating, P., Koenig, W., Thorand, B., Haastert, B., Holle, R., Illig, T., Rathmann, W., Seissler, J., Wichmann, H.E., Kolb, H.: Systemic monocyte chemoattractant protein-1 concentrations are independent of type 2 diabetes or parameters of obesity: Results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4). Eur J Endocrinology 154, 311-317 (2006)

Hinney, A., Bettecken, T., Tarnow, P., Brumm, H., Reichwald, K., Lichtner, P., Scherag, A., Nguyen, T.T., Schlumberger, P., Rief, W., Vollmert, C., Illig, T., Wichmann, H.E., Schäfer, H., Platzer, M., Biebermann, H., Meitinger, T., Hebebrand, J.: Prevalence, Spectrum, and Functional Characterization of Melanocortin-4 Receptor Gene Mutations in a Representatove Population-Based Sample and Obese Adults from Germany. J Clin Endocrinol Metab 91, 1761-1769 (2006)

Jamra, A.J., Villela, A.W., Klein, K., Becker, T., Schulze, T.G., Schmael, C., Deschner, M., Klopp, N., Illig, T., Propping, P., Cichon, S., Rietschel, M., Nöthen, M.M., Schumacher, J.: No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia. Psychiatr Genet 16, 91 (2006)

Kamm, C., Asmus, F., Mueller, J., Mayer, P., Sharma, M., Muller, U.S., Beckert, S., Ehling, R., Illig, T., Wichmann, H.E., Poewe, W., Mueller, J.C., Gasser, T.: Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia. Neurology 67, 1857-1859 (2006)

Rabstein, S., Unfried, K., Ranft, U., Illig, T., Kolz, M., Rihs, H.P., Mambetova, C., Vlad, M., Brüning, T., Pesch, B.: Variation of the N-Acetyltransferase 2 Gene in a Romanian and a Kyrgyz Population. Cancer Epidemiol Biomarkers Prev 15(1), 138-141 (2006)

Riemenschneider, M., Konta, L., Friedrich, P., Schwarz, S., Taddei, K., Neff, F., Padovani, A., Kölsch, H., Laws, S.M., Klopp, N., Bickeböller, H., Wagenpfeil, S., Mueller, J.C., Rosenberger, A., Diehl-Schmid, Archetti, S., Lautenschlager, N., Borroni, B., Müller, U., Illig, T., Heun, R., Egensberger, R., Schlegel, J., Förstl, H., Martins, R.N., the German sib-pair study group and Kurz, : A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease. Hum Mol Genet 15(16), 2446-2456 (2006)

Santhiya, S.T., Söker, T., Klopp, N., Illig, T., Prakash, M.V.S., Selvaraj, B., Gopinath, M., Graw, J.: Identification of a novel, putative cataract-causing allele in CRYAA (G98R) in an Indian family. Molecular Vision 12, 768.773 (2006)

Schedel, M., Depner, M., Schoen, C., Weiland, S.K., Vogelberg, C., Niggemann, B., Lau, S., Illig, T., Klopp, N., Wahn, U., von Mutius, E., Nickel, R., Kabesch, M.: The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations. Respiratory Research 7:91 (2006)

Scheiner, D.: Genetic Analysis of DNA Repair Polymorphisms in Lung Cancer Patients. Master`s Thesis, 91 S. + Anhang (2006)

Sedlmeier, E.: Candidate Gene Approach for Parameter of Metabolic Syndrome. Master`s Thesis, 71 S. + Anhang (2006)

Weidinger, S., Novak, N., Klopp, N., Baurecht, H., Wagenpfeil, S., Rummler, L., Ring, J., Behrendt, H., Illig, T.: Letter to the Editor. Lack of associations between Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and atopic eczema. J Allergy Clin Immunol 118, 277-279 (2006)

Weidinger, S., Illig, T., Baurecht, H., Irvine, A.D., Rodriguez, E., Diaz-Lacava, A., Klopp, N., Wagenpfeil, S., Zhao, Y., Liao, H., Lee, S.P., Palmer, C.N.A., Jenneck, C., Maintz, L., Hagemann, T., Behrendt, H., Ring, J., Nothen, M.M., McLean, I., Novak, N.: Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations. J Allergy Clin Immunol 118, 214-219 (2006)
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