TOPIC "Aerosol Toxicology" Staff

Dr. Mathilde Noemie Delaval
Scientist

Phone: +49 89 3187 49277
E-mail
Building/Room: 107/ 234

 

Research Biography

Mathilde Delaval joined CMA in July 2021 as a research scientist. She earned her PhD degree in Toxicology in 2015 at the University Paris Diderot, France. During her studies, she investigated the adverse effects of nanoparticles on the human airways using in vitro lung models. Her research activities are focused on the evaluation of air pollutants (e.g. nanoparticles, ambient particles, electronic cigarette aerosols) on human health, with a specialization in pulmonary toxicology and in vitro-based new approach methodologies (NAMs).

 

Project

ALIAS-Lung project: Optimization of the ALI exposure system for long-term exposure 

 

Education

  • 2015 PhD in Toxicology, University Paris Diderot, Paris, France. Thesis: Effects of Cerium Oxide nanoparticles on the human respiratory epithelium in vitro.
  • 2012 MSc in (Eco-)Toxicology, National Museum of Natural History (MNHN), Paris, France
  • 2011 MSc in Public Health and Environmental Risks, University Paris Descartes, Paris, France
  • 2010 BSc in Cell Biology and Health, University of Occidental Brittany, Brest, France

 

Professional experience

  • 2021-present: Research Scientist at the Comprehensive Molecular Analytics (CMA) cooperation group, Munich, Germany
  • 2019-2021: Postdoctoral researcher in Environmental Toxicology and Nanotoxicology at the Institute of Environmental Medicine (IMM), Karolinska Institutet, Stockholm, Sweden
  • 2017-2019: Postdoctoral researcher in Pulmonary Toxicology, Institute of Anatomy, University of Bern, Switzerland

 

List of publications

Scala G., Delaval M.N., Mukherjee S.P., Federico A., Khaliullin T.O., Yanamala N., Fatkhutdinova L.M., Kisin E.R., Greco D., Fadeel B., Shvedova A.A. Carbon, 2021. Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice. https://doi.org/10.1016/j.carbon.2021.03.045

Gallud A., Delaval M., Kinaret P., Marwah V.S., Fortino V., Ytterberg J., Zubarev R., Skoog T., Kere J., Correia M., Loeschner K., Al-Ahmady Z., Ruiz J., Astruc D., Monopoli M., Handy R., Moya S., Savolainen K., Alenius H., Greco D. & Fadeel B. Advanced Science, 2020. Multi-parametric profiling of engineered nanomaterials: Unmasking the surface coating effect. https://onlinelibrary.wiley.com/doi/10.1002/advs.202002221

Jonsdottir, H. R., Delaval, M., Leni, Z., Keller, A., Brem, B. T., Siegerist, F., Schönenberger D., Durdina L., Elser M., Burtscher H., Liati A. & Geiser, M. Communications Biology, 2019. Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells. https://www.nature.com/articles/s42003-019-0332-7

M. Delaval, D. Egli, P. Schüpfer, C. Benarafa, M. Geiser, H. Burtscher. Journal of Aerosol Science, 2018. Novel instrument to generate representative e-cigarette vapors for physicochemical particle characterization and in-vitro toxicity. www.sciencedirect.com/science/article/pii/S002185021830291X

M. Delaval, W. Wohlleben, R. Landsiedel, A. Baeza-Squiban, S. Boland. Archives of Toxicology, 2017. Assessment of the oxidative potential of nanoparticles by the cytochrome c assay: assay improvement and development of a high throughput method to predict the toxicity of nanoparticles. link.springer.com/article/10.1007%2Fs00204-016-1701-3