TOPIC IV "Aerosol Mutagenesie" Staff

TOPIC IV "Aerosol Mutagenesis" Staff

Xiao Wu
PhD Student



Xiao Wu studied Environmental Health and Occupational Health at the Shandong University and received his master degree in 2012. As a PhD student, he is in the cooperation group CMA at Helmholtz Zentrum München. The main goal of his research is to investigate the oxidative stress induced by particulate matters (PM) exposure on human body with LC/ LC-MS methods. The work runs in the frame of the “Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health - HICE” and “Cooperative Health Research in the Augsburg Region - KORA”. Robust LC/ LC-MS methods to determine oxidative stress related biomarkers have been developed, optimized, and established. They could be successfully applied on three different projects: 1) a cohort of travelers has been recruited. Urine samples were collected before and after travel and analysed to investigate the effects of air pollution; 2) Urine samples from volunteers of Augsburg region have been collected and analysed to investigate the association between the long term ultrafine particulate matters (UFPM) exposure and human health (KORA cohort); 3) samples from cigarette smoke exposed mice were collected and oxidative stress burden was investigated.

Thesis: Quantification of health-relevant substances in ambient aerosol of different origin using HPLC and LC-MS/MS. Development of LC-MS/MS techniques for investigating the impact of aerosols on biological systems.