High resolution mass spectrometry can determine molecular masses with extreme high accuracy and resolution. This enables the assignment of sum formulas and graphical data analysis of high complex mixtures as e.g. crude oil, combustion and ambient aerosol samples, containing often up to 50.000 individual species.

One main goal of the high resolution mass spectrometry group is the development and technical refinement of techniques for sample introduction and ionization as well as application of coupling schemes to separation devices. This basic research is motivated by the need of enhanced and adapted analytical instruments to enable a deeper view into the chemical structures of complex mixtures.

Actually following high resolution mass spectrometers are operated:
Two Fourier-Transformation Ion Cyclotron Mass Spectrometers (FTICR MS, Solarix and Apex II Ultra) sharing a 7 Tesla supra conducting magnet and one Orbitrap system (LTQ-XL). Ion sources as MALDI (355nm), electrospray (ESI) and atmospheric pressure chemical (APCI) as well as photoionization (APPI) are available. Gas chromatographic separation and a thermal balance are coupled to FTICR MS, opening a further dimension of resolving power.

Scientists involved: Anika Neumann, Christoph Rüger, Martin Sklorz

Supported by: Thomas Kröger-Badge (electronic engineer), Andrea Lehmann (technician)