Biostatistics and trial design

Statistical and epidemiologic methods are used all over the Institute of Diabetes Research.

Analyses of the extensive data from the institutes cohort studies (TEDDY, BABYDIAB und BABYDIET) to identify risk factors and time windows for the genesis of type 1 diabetes facilitate the development of prevention and treatment of the disease.

To develop guidelines for clinical practice evidence of high quality is needed. This evidence is generated in randomized controlled clinical trials. Those have to be set up and analyzed appropriately. The randomized clinical trials of the institute like the Fr1da Insulin Intervention Trial or POInT (Primary Oral Insulin Trial) examine the safety and efficacy of different interventions to prevent type 1 diabetes.

Further we investigate innovative trial designs that utilize existing knowledge efficiently and thus speed up research, for example by meta-analyzing trials or by decreasing the number of participants needed in a trial without limiting its validity. 

Contact person: Andreas Weiß
Phone: +49 89 3187-43017