Completed projects

Multimodal non-drug therapy for persons with cognitive decline in day-care institutions with short-term interventions for informal caregivers by telephone to strengthen the compatibility of care and work  („DeTaMAKS“).
Team:Dr. H. Seidl, Prof. Dr. R. Holle
Funding:German National Association of the Statutory Health Insurance and Long-Term Care Insurance Funds (GKV-Spitzenverband) and the Bavarian State Ministry of Health and Care
Duration:3 years
ISRCTN Register No.16412551
Description:People with dementia and their informal caregivers wish to delay a transfer to a nursing home and the resulting loss of independence as long as possible. However, due to other responsibilities, the family caregivers are not always capable of performing home care without further help. Day-care institutions offer an alternative, but are seldom used.
Via specific support in these centers, abilities of daily living could be maintained for a longer period of time and thus reduce the burden for informal caregivers as well as delay the transfer to a nursing home.

Under the leadership of Prof. Dr. Elmar Gräßel and PD Dr. Katharina Luttenberger from the Department of Psychiatry and Psychotherapy, Medical Psychology and Medical Sociology, Friedrich-Alexander-University Erlangen-Nuremberg, a cluster-randomized controlled multicenter intervention study is conducted to investigate, whether a multimodal non-drug therapy can sustain the self-dependence of the patients.

The IGM is in charge of the economic analysis, like determining health care utilization or measuring the impact on the caregivers’ quality of life.
Objectives:The intervention’s main objectives are promoting and stabilizing abilities of daily living of people with mild cognitive impairment or early dementia. The primary outcomes are measured for a 6-month intervention-interval with the performance test E-ADL and MoCa.

The secondary outcome measurement is the subjective burden for informal caregivers. In the 2-year analysis, we also measure the duration of home care as surrogate-parameter for the delayed transfer to the nursing home.

Health-economic outcomes are health related quality of life and cost of health care utilization caused by patients and informal caregivers.
Methods:Thirty-two participating day-care institutions from four different federal states are randomized and 346 visitors of day-care centers with mild cognitive impairment, mild or moderate dementia as well as their informal caregivers are included in the study.

Data collection is carried out by telephone interviews with the informal caregivers at baseline, after 6, 12, and 24 months and by questionnaires completed by the day-care centers at baseline, after 12 and 24 months.

The IGM evaluates the health care cost caused by dementia patients and family caregivers and calculates the mean differences in cost between intervention and control group.
Generic health-related quality of life of patients and informal caregivers is measured with the EQ-5D-5L and the EQ visual analogue scale (VAS).