Publications

Scientific publications:

[8]   “Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A” G. Jürjens, S. M. M. Schuler, M. Kurz, S. Petit, C. Couturier, F. Jeannot, F. Nguyen, R. C. Wende, P. E. Hammann, D. N. Wilson, E. Bacqué, C. Pöverlein, A. Bauer, Angew. Chem., 2018, 57, 12157-12161; Angew. Chem. Int. Ed. 2018, 57, 12157-12161.

[7]   “Targeting TRAF6 E3 ligase activity with a small molecule inhibitor combats autoimmunity” J. K. Brenke, G. M. Popowicz, K. Schorpp, I. Rothenaigner, M. Roesner, I. Meininger, C. Kalinski, L. Ringelstetter, O. R’kyek, G. Jürjens, M. Vincendeau, O. Plettenburg, M. Sattler, D. Krappmann, K. Hadian, J. Biol. Chem. 2018, 293, 13191-13203.

[6]   “2-Iodoxybenzoic Acid Tosylates: the Alternative to Dess-Martin Periodinane Oxidizing Reagents” M. S. Yusubov, P. S. Postnikov, R. Y. Yusubova, A. Yoshimura, G. Jürjens, A. Kirschning, V. V. Zhdankin, Adv. Synth. Catal. 2017, 359, 3207-3216.

[5]   “Lessons from the Synthetic Chemist Nature” G. Jürjens, A. Kirschning, D. Candito, Nat. Prod. Rep2015, 32, 723-737.

[4]   “Pushing Flow Chemistry to New Limits: Development of a Flow Process towards Spirangien A.” G. Jürjens, A. Kirschning, ChemCatChem 2014, 6, 2798-2800.

[3]   “Synthesis of a cytotoxic ansamycin hybrid.” G. Jürjens, A. Kirschning, Org. Lett. 2014, 16, 3000-3003.

[2]   “Bioreduction of aryl azides during mutasynthesis of new ansamitocins.” L. Mancuso, G. Jürjens, J. Hermane, K. Harmrolfs, S. Eichner, J. Fohrer, W. Collisi, F. Sasse, A. Kirschning, Org. Lett. 2013, 17, 4442-4445.

[1]   “Tri-substituted imidazole analogues of SB203580 as inducers for cardiomyogenesis of human embryonic stem cells.” J.-L. Low, G. Jürjens, J. Seayad, J. Seow, S. Ting, F. Laco, S. Reuveny, S. Oh, C. L. L. Chai, Bioorg. Med. Chem. Lett. 2013, 23, 3300-3303.

 

Patents:

K. Hadian; J. K. Brenke; O. Plettenburg; G Jürjens, Preparation of triazolopyridazinyl and imidazopyridazinyl pyrazoles as TRAF 6 inhibitors, Schutzrecht WO 2018050286 (2018)

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