Publications

2019
Giannios, I. ; Serafimidis, I. ; Anastasiou, V. ; Pezzolla, D. ; Lesche, M. ; Andree, C. ; Bickle, M. ; Gavalas, A.
Protein methyltransferase inhibition decreases endocrine specification through the upregulation of Aldh1b1 expression.
Stem Cells 37, 640-651 (2019)
Mameishvili, E. ; Serafimidis, I. ; Iwaszkiewicz, S. ; Lesche, M. ; Reinhardt, S. ; Bölicke, N. ; Büttner, M. ; Stellas, D. ; Papadimitropoulou, A. ; Szabolcs, M. ; Anastassiadis, K. ; Dahl, A. ; Theis, F.J. ; Efstratiadis, A. ; Gavalas, A.
Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
Proc. Natl. Acad. Sci. U.S.A. 116, 20679-20688 (2019)
2017
Serafimidis, I. ; Rodriguez-Aznar, E. ; Lesche, M. ; Yoshioka, K. ; Takuwa, Y. ; Dahl, A. ; Pan, D. ; Gavalas, A.
Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.
PLoS Biol. 15:e2000949 (2017)
2016
Anastasiou, V. ; Ninou, E. ; Alexopoulou, D. ; Stertmann, J. ; Müller, A. ; Dahl, A. ; Solimena, M. ; Speier, S. ; Serafimidis, I. ; Gavalas, A.
Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice.
Diabetologia 59, 139-150 (2016)
2013
Gavalas, A. ; Lan, T.H. ; Liu, Q. ; Corrêa, I.R. ; Javitch, J.A. ; Lambert, N.A.
Segregation of family A G protein-coupled receptor protomers in the plasma membrane.
Mol. Pharmacol. 84, 346-352 (2013)
Ioannou, M. ; Serafimidis, I. ; Arnes, L. ; Sussel, L. ; Singh, S. ; Vasiliou, V. ; Gavalas, A.
ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools.
Dev. Biol. 374, 153-163 (2013)
2011
Bami, M. ; Episkopou, V. ; Gavalas, A. ; Gouti, M.
Directed neural differentiation of mouse embryonic stem cells is a sensitive system for the identification of novel Hox gene effectors.
PLoS ONE 6:e20197 (2011)
Gouti, M. ; Briscoe, J. ; Gavalas, A.
Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates.
Stem Cells 29, 858-870 (2011)
Serafimidis, I. ; Heximer, S. ; Beis, D. ; Gavalas, A.
G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis.
Mol. Cell. Biol. 31, 4442-4453 (2011)
2010
Poulou, M. ; Bell, D.R. ; Bozonelos, K. ; Alexiou, M. ; Gavalas, A. ; Lovell-Badge, R. ; Remboutsika, E.
Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM "off-on" gene switch.
PLoS ONE 5:e12488 (2010)