Publications

2021

Spears, E. ; Serafimidis, I. ; Powers, A.C. ; Gavalas, A.

Debates in pancreatic beta cell biology: Proliferation versus progenitor differentiation and transdifferentiation in restoring β cell mass.

Front. Endocrin. 12:722250 (2021)

2020

Stefanovic, S. ; Laforest, B. ; Desvignes, J.P. ; Lescroart, F. ; Argiro, L. ; Maurel-Zaffran, C. ; Salgado, D. ; Plaindoux, E. ; De Bono, C. ; Pazur, K. ; Théveniau-Ruissy, M. ; Béroud, C. ; Puceat, M. ; Gavalas, A. ; Kelly, R.G. ; Zaffran, S.

Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation.

eLife 9:e55124 (2020)

2019

Giannios, I. ; Serafimidis, I. ; Anastasiou, V. ; Pezzolla, D. ; Lesche, M. ; Andree, C. ; Bickle, M. ; Gavalas, A.

Protein methyltransferase inhibition decreases endocrine specification through the upregulation of Aldh1b1 expression.

Stem Cells 37, 640-651 (2019)

Mameishvili, E. ; Serafimidis, I. ; Iwaszkiewicz, S. ; Lesche, M. ; Reinhardt, S. ; Bölicke, N. ; Büttner, M. ; Stellas, D. ; Papadimitropoulou, A. ; Szabolcs, M. ; Anastassiadis, K. ; Dahl, A. ; Theis, F.J. ; Efstratiadis, A. ; Gavalas, A.

Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.

Proc. Natl. Acad. Sci. U.S.A. 116, 20679-20688 (2019)

2017

Serafimidis, I. ; Rodriguez-Aznar, E. ; Lesche, M. ; Yoshioka, K. ; Takuwa, Y. ; Dahl, A. ; Pan, D. ; Gavalas, A.

Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.

PLoS Biol. 15:e2000949 (2017)

2016

Anastasiou, V. ; Ninou, E. ; Alexopoulou, D. ; Stertmann, J. ; Müller, A. ; Dahl, A. ; Solimena, M. ; Speier, S. ; Serafimidis, I. ; Gavalas, A.

Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice.

Diabetologia 59, 139-150 (2016)

2013

Gavalas, A. ; Lan, T.H. ; Liu, Q. ; Corrêa, I.R. ; Javitch, J.A. ; Lambert, N.A.