Assay Development and Screening

Head: Dr. Kamyar Hadian

Established in May 2010, the Assay Development and Screening Platform is part of the future Drug Discovery Center at Helmholtz Zentrum München. In collaboration with researchers at Helmholtz Zentrum München, biochemical and cellular assay systems shall be developed to search for new chemical molecules that influence specific biological processes. To this end, the Assay Development and Screening Platform is developing state-of-the-art devices and assay technologies and is working on the development of new assay methods. The projects of the Assay Development and Screening Platform are designed to find new molecules that interfere with DNA repair processes and the cell cycle.

Portfolio

  • Consultation and assistance in the design of in vitro and cellular screening assays
  • Implementation of robotics-based screening
  • Evaluation of screening data
  • Establishment and maintenance of small molecule libraries

Technologies

  • Fully automatic liquid handling system
  • EnVision plate reader (Measurement of fluorescence, absorption, time-resolved fluorescence (TRF), alphascreen and luminescence)
  • Microscale thermophorese (protein/protein, protein/DNA,protein/compound interaction analyses)

Please visit the website of the Assay Development and Screening for more information