Scientific highlights

11.07.2019

Martin Hrabě de Angelis to become a member of the Leopoldina

Prof. Dr. Martin Hrabě de Angelis has become a member of the German Academy of Sciences Leopoldina for his services to metabolic genetics. The director of the Institute for Experimental Genetics at Helmholtz Zentrum München and Chair at Technische Universität München is an internationally leading geneticist with a focus on diabetes research. Leopoldina President Prof. Dr. Jörg Hacker presented Hrabě de Angelis with the admission certificate yesterday, Wednesday, July 10, 2019.

Leopoldina President Prof. Dr. Jörg Hacker (right) presents Prof. Dr. Martin Hrabě de Angelis with the certificate of admission to the National Academy of Sciences © Markus Scholz/ Leopoldina

The National Academy of Sciences Leopoldina with its 1,600 members is representing German science in international committees and provides science-based advice for politics and society. Its members are outstanding research personalities with excellent scientific achievements.

Martin Hrabě de Angelis explores genes in mice and humans that play a role in the metabolism and development of diabetes. He is the co-founder of the German Centre for Diabetes Research, which aims to develop new prevention approaches and therapies, and of which he is a board member. He established the German Mouse Clinic at Helmholtz Zentrum München where animal models are used to investigate the influence of genes and the environment on health and disease. With this systematic approach, he succeeded in uncovering causal relationships for metabolic disorders that are relevant for mice and humans. Hrabě de Angelis and his research partners were also able to show for the first time that dietary obesity and diabetes can be passed on to the next generation beyond the generational borders.

Since 2000, Martin Hrabě de Angelis has been director of the Institute for Experimental Genetics at Helmholtz Zentrum München and was appointed Chair of Experimental Genetics at Technische Universität München in 2003.

He has contributed significantly to the networking of scientific infrastructures in genetics and has promoted the establishment of national and international research consortia. Since 2008 he coordinates the European research network "Infrafrontier". The International Mouse Phenotyping Consortium (IMPC), which is developing the first functional encyclopedia of the mammalian genome, is based on the systemic phenotyping of disease models introduced by the German Mouse Clinic.

Martin Hrabě de Angelis has received honorary doctorates from the Ludwig-Maximilians-University Munich, the Technical University Dresden and the University Leipzig for his services to scientific collaborations and joint publications in the field of diabetes research.

As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle. The Helmholtz Zentrum München has about 2,300 staff members and is headquartered in Neuherberg in the north of Munich. Helmholtz Zentrum München is a member of the Helmholtz Association, a community of 19 scientific-technical and medical-biological research centers with a total of about 37,000 staff members. 

The National Academy of Sciences Leopoldina was founded in 1652 as a scientific-medical society and currently has over 1,600 national and international members from all fields of science. It is the oldest academy in Germany and was named the National Academy of Sciences by the Federal Government and the Länder in 2008. In this function, it has two tasks: to represent German science abroad and to advise politicians and the public.  

The German Center for Diabetes Research (DZD) is a national association that brings together experts in the field of diabetes research and combines basic research, translational research, epidemiology and clinical applications. The aim is to develop novel strategies for personalized prevention and treatment of diabetes. Members are Helmholtz Zentrum München – German Research Center for Environmental Health, the German Diabetes Center in Düsseldorf, the German Institute of Human Nutrition in Potsdam-Rehbrücke, the Paul Langerhans Institute Dresden of the Helmholtz Zentrum München at the University Medical Center Carl Gustav Carus of the TU Dresden and the Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Zentrum München at the Eberhard-Karls-University of Tuebingen together with associated partners at the Universities in Heidelberg, Cologne, Leipzig, Lübeck and Munich. 

The research objective of the Institute of Experimental Genetics (IEG) is to elucidate the causes and pathogenesis of human diseases. Due to its prominent role in interdisciplinary and international consortia, the IEG is a global leader in the systemic study of mouse models for human diseases and the elucidation of involved genes. The main focus is on metabolic diseases such as diabetes. The IEG is part of the Helmholtz Diabetes Center (HDC).

The German Mouse Clinic (GMC) as an open access phenotyping platform offers comprehensive phenotyping of mouse models in a systemic primary screen evaluating numerous physiological pathways within a variety of therapeutic areas. The GMC is headed by the Institute of Experimental Genetics and is a consortium with following members: the Helmholtz Zentrum München, the Ludwig-Maximilians-University, the Technical University Munich and the Universities of Bonn and Heidelberg. Scientists from these institutions with an expert knowlegde from various fields of mouse physiology and pathology work side-by-side in close cooperation with clinicians in the GMC.

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