The Obese Taste Bud Study

What is the aim of the study?

Taste is crucial for the preference of certain foods. Previous studies indicate, that morbid obesity is accompanied by a loss of taste buds on the tongue. The aim of this project is to find out underlying cellular mechanism, identification of what changes the taste cells and how this may affect eating behavior.

Who may participate?

People who meet the following requirements:

  • men and women with normal weight or with obesity
  • between the ages of 18 and 69

You may not participate if you:

  • suffer from a serious illness (e. g. cancer, Altzheimer's disease, kidney or liver diseases)
  • when you are pregnant or breastfeeding
  • are in the process of a systemic therapy with the use of glucocorticoids, antidepressants or anticonvulsant drugs

What happens during the study?

You will undergo the following examinations:

  • determination of body measurements (weight, height, BMI etc.)
  • measurement of body fat and muscle mass (bioimpedance analysis)
  • measurement of insulin sensitivity
  • examination of taste sensitivity
  • an odor screening
  • blood examinations
  • determination of taste bud density 
  • saliva sample and tongue smear
  • extraction of 6-8 taste buds

How long does the participation at the study take and will there be a remuneration?

The examinations take place over the course of two days (7h in total) and you will receive 50,-€ expense allowance.

You are interested?

Do not hesitate to contact us!

The study leader is Dr. Imke Schamarek from the Endocrinology Department at the University Clinic and the scientific contact is Dr. Kerstin Rohde-Zimmermann from the Group Clinical Obesity Research from the HI-MAG.

Tel:      +49 341 97 13116

Email:  OTBnoSp@m@medizin.uni-leipzig.de