Biology Core Facility

Profile

Oxygenation map of mouse brain
Oxygenation map of mouse brain

The group „Core Facilities“ is centered around provision and development of cell lines and animal models for optoacoustic imaging. Our portfolio includes transgenic cancer cell lines stably expressing iRPF720 and tyrosinase (both labels provide good contrast in optoacoustic imaging), systems for retroviral gene transfer and various chemical labels for primary cells. This allows us to mark primary cells and cell lines upon request. Besides we do ectopic and orthotropic tumor implantations to visualize tumor vasculature and monitor certain hallmarks of cancer. These models are used also to perform clinically relevant treatment studies and execute immunotherapy-based experiments using primary T-cells and macrophages.

To advance the field of optoacoustics to a new era we have developed Cre/LoxP based mouse reporter lines that will enable us to perform lineage tracing and cell tracking experiments. Finally it will provide a tool to visualize mouse anatomy and physiology with unprecedented resolution and distinctness.

Group leader

Image Name Job Title E-mail Telephone Building/Room
Dr. Bengel,
Doris
Laboratory manager E-mail +49 (0) 89 3187 4138 56/028a

People

Image Name Job Title E-mail Telephone Building/Room
Dr. Bengel,
Doris
Laboratory manager E-mail +49 (0) 89 3187 4138 56/028a
Anzenhofer,
Pia
Technician E-mail +49 (0) 89 3187 1595 43b/101
Glasl,
Sarah
Technician E-mail +49 (0) 89 3187 4703 43b/101
Klemm,
Uwe
Technician E-mail +49 (0) 89 3187 4703 43b/101

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