Publications

TOP 10

Rios Garcia M, Steinbauer B, Kshitij S, Singhal M, Mattijssen F, Maida A, Christian S, Hess-Stumpp H, Augustin HG, Müller-Decker K, Nawroth PP, Herzig S, Berriel Diaz M: Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence. Cell Metabolism 2017; 26(6):842-855.e5.
DOI: 10.1016/j.cmet.2017.09.018 

Rohm M, Schäfer M, Laurent V, Ekim Üstünel B, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri EZ, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S: An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. Nature Medicine 2016; 22(10):1120-1130.
DOI: 10.1038/nm.4171

de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S: microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis. The EMBO Journal 2015; 34(3):344-360.
DOI: 10.15252/embj.201490464

Rohm M, Sommerfeld A, Strzoda D, Jones A, Sijmonsma TP, Rudofsky G, Wolfrum C, Sticht C, Gretz N, Zeyda M, Leitner L, Nawroth PP, Stulnig TM, Berriel Diaz M, Vegiopoulos A, Herzig S: Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue. Cell Metabolism 2013; 17(4):575-585.
DOI: 10.1016/j.cmet.2013.02.010

Rose AJ, Berriel Diaz M, Reimann A, Klement J, Walcher T, Krones-Herzig A, Strobel O, Werner J, Peters A, Kleyman A, Tuckermann JP, Vegiopoulos A, Herzig S: Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor. Cell Metabolism 2011 ; 14(1):123-130.
DOI: 10.1016/j.cmet.2011.04.010

Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Berriel Diaz M, Herzig S: Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia. Cell Metabolism 2011; 13(4):389-400.
DOI: 10.1016/j.cmet.2011.02.011

Vegiopoulos A, Müller-Decker K, Strzoda D, Schmitt I, Chichelnitskiy E, Ostertag A, Berriel Diaz M, Rozman J, Hrabe de Angelis M, Nüsing RM, Meyer CW, Wahli W, Klingenspor M, Herzig S: Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes. Science 2010; 328(5982):1158-1161.
DOI: 10.1126/science.1186034

Lemke U, Krones-Herzig A, Berriel Diaz M, Narvekar P, Ziegler A, Vegiopoulos A, Cato ACB, Bohl S, Klingmüller U, Screaton RA, Müller-Decker K, Kersten S, Herzig S: The glucocorticoid receptor controls hepatic dyslipidemia through Hes1. Cell Metabolism 2008; 8(3):212-223.
DOI: 10.1016/j.cmet.2008.08.001

Herzig S, Hedrick S, Morantte I, Koo SH, Galimi F, Montminy M: CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature 2003; 426(6963):190-193.
DOI: 10.1038/nature02110

Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 2001; 413(6852):179-183.
DOI: 10.1038/35093131

2019

Klepac K, Georgiadi A, Tschöp M, Herzig S: The role of brown and beige adipose tissue in glycaemic control. Mol Aspects Med 2019; in press

Rohm M, Zeigerer A, Machado J, Herzig S: Energy metabolism in cachexia. EMBO Reports 2019; 20, e47258.
DOI: 10.15252/embr.201847258

Ducommun S, Deak M, Zeigerer A, Göransson O, Seitz S, Collodet C, Madsen AB, Jensen TE, Viollet B, Foretz M, Gut P, Sumpton D, Sakamoto K: Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates. Cell Signal 2019; 57:45-57.
DOI: 10.1016/j.cellsig.2019.02.001

Kindler D, Sousa SS, Schweizer S, Lerch S, Klingenspor M, Herzig S, Vegiopoulos A: A novel growth factor-dependent thermogenic brown adipocyte cell line from defined precursor cells. bioRxiv 2019 565168.
DOI: 10.1101/565168

Guillamat Prats R, Rami M, Herzig S, Steffens S: Endocannabinoid signaling in atherosclerosis and related metabolic complications. Thrombosis and Haemostasis 2019; 119(4):567-575.
DOI: 0.1055/s-0039-1678738

Glantschnig C, Koenen M, Gil-Lozano M, Karbiener M, Pickrahn I, Williams-Dautovich J, Patel R, Cummins CL, Giroud M, Hartleben G, Vogl E, Blüher M, Tuckermann J, Uhlenhaut H, Herzig S, Scheideler M: A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signalling. Faseb Journal 2019; fj201801385RR.
DOI: 10.1096/fj.201801385RR

2018

Kretschmer N, Deutsch A, Durchschein C, Rinner B, Stallinger A, Higareda-Almaraz J C, Scheideler M, Lohberger B, Bauer R: Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction. Molecules 2018; 23(11)

Higareda-Almaraz J C, Karbiener M, Giroud M, Pauler F M, Gerhalter T, Herzig S, Scheideler M: Norepinephrine triggers an immediate-early regulatory network response in primary human white adipocytes. BMC Genomics 2018; 19(1):794

Wolff G, Taranko A E, Meln , Weinmann J, Sijmonsma T, Lerch S, Heide D, Billeter A T, Tews D, Krunic D, Fischer-Posovszky P, Müller-Stich B P, Herzig S, Grimm D, Heikenwälder M, Kao W W, Vegiopoulos A: Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis. Mol Metab 2018; 19:97-106

Ali Khan A, Hansson J, Weber P, Foehr S, Krijgsveld J, Herzig S, Scheideler M: Comparative secretome analyses of primary murine white and brown adipocytes reveal novel adipokines. Mol Cell Proteomics 2018; 17(12):2358-2370

Ghandour R A, Colson C, Giroud M, Maurer S, Rekima S, Ailhaud G, Klingenspor M, Amri E Z, Pisani D F: Impact of dietary ω3 polyunsaturated fatty acid supplementation on brown and brite adipocyte function. J Lipid Res 2018; 59, 452-461

Görgülü K, Diakopoulos K N, Ai J, Schoeps B, Kabacaoglu D, Karpathaki A F, Ciecielski K J, Kaya-Aksoy E, Ruess D A, Berninger A, Kowalska M,  Stevanovic M, Wörmann S M, Wartmann T, Zhao Y, Halangk W, Voronina S, Tepikin A, Schlitter A M, Steiger K, Artati A, Adamski J, Aichler M, Walch A, Jastroch M,  Hartleben G, Mantzoros C S, Weichert W, Schmid R M, Herzig S, Krueger A, Sainz B, Lesina M, Algül H: Levels of Atg5 determine pancreatic tumor progression and metastasis in mice. Gastroenterol 2018; 156(1):203-217

Fisker Schmidt S, Rohm M, Herzig S, Berriel Diaz M: Cancer cachexia: More than skeletal muscle wasting. Trends Cancer 2018; 4(12):849-860

Hess J, Unger K, Maihoefer , Schüttrumpf L, Wintergerst L, Heider T, Weber P, Marschner S, Braselmann H, Samaga D, Kuger S, Pflugradt U, Baumeister P, Walch A, Woischke C, Kirchner T, Werner M, Werner K, Baumann M, Budach V, Combs S E, Debus J, Grosu A L, Krause M, Linge A, Rödel C, Stuschke M, Zips D, H F Zitzelsberger, Ganswindt U, Henke M, Belka C: A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV-infection. AACRJ 2018; 10.1158/1078-0432.CCR-18-0776

Krahmer N, Najafi B, SchuedernF, Quagliarini F, Steger M, Seitz S, Kasper R, Salinas F, Cox J, Uhlenhaut N H, Walther T C, Jungmann R, Zeigerer A, Borner G H H, Mann M: Organellar proteomics and phospho-proteomics reveal subcellular reorganization in diet-induced hepatic steatosis. Dev Cell 2018; 47(2):205-221

Bayindir-Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, Billeter A T, Babaei R, Krunic D, Ketscher L, Spielmann N, Hrabe de Angelis M, Ruas J L, Müller-Stich B P, Heikenwalder M, Lichter P, Herzig S, Vegiopoulos A: Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. EMBO Mol Med 2018; 10(8): e8613

Maida A, Zota A, Vegiopoulos A, Appak-Baskoy S, Augustin HG, Heikenwalder M, Herzig S, Rose AJ: Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance. J Nutr Biochem 2018; 57:189-196

Terlecki-Zaniewicz L, Lämmermann I, Latreille J, Bobbili M, Pils V, Schosserer M, Weinmüllner R, Dellago H, Skalicky S, Pum D, Higareda Almaraz J, Scheideler M, Morizot F, Hackl M, Gruber F, Grillari J: Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype. Aging 2018; 10(5):1103-1132

Jabs M, Rose A J, Lehmann L H, Taylor J, Moll I, Sijmonsma T P, Herberich S E, Sauer S W, Poschet G, Federico G, Mogler C, Weis E M, Augustin H G, Yan M, Gretz N, Schmid R M, Adams R H, Gröne H J, Hell R, Okun J G, Backs J, Nawroth P P, Herzig S, Fischer A: Inhibition of endothelial Notch signaling impairs fatty 1 acid transport and leads to metabolic and vascular remodeling of the adult heart. Circulation 2018; 137(24):2592-2608

Riedinger C, Mendler M, Schlotterer A, Fleming T, Okun J, Hammes H P, Herzig S, Nawroth P P: High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans. J Biol Chem 2018; 293(13):4845-4859.

Lämmermann I, Terlecki-Zaniewicz L, Weinmüllner R, Schosserer M, Dellago H, Dargen de Matos Branco A, Autheried D, Sevcnikar B, Kleissl L, Berlin I, Morizot F, Jejeune F, Fuzzati N, Forestier S, Toribio A, Tromeur A, Weinberg L, Higareda Almaraz JC, Scheideler M, Rietveld M, El Ghalbzouri A, Tschachler E, Gruber F, Grillari J: Blocking negative effects of senescence in human skin fibroblasts with a plant extract. NPJ Aging Mech Dis 2018; 4:4

Babaei R, Schuster M, Meln I , Lerch S, Ghandour R A, Pisani D F, Bayindir-Buchhalter I, Marx J, Wu S, Billeter A T, Krunic D, Mauer J, Lee Y-H, Granneman J G, Fischer L, Müller-Stich B P, A Ez-Zoubir , Kershaw E E, Heikenwälder M, Herzig S, Vegiopoulos A: ak-TGFbeta crosstalk links transient adipose tissue inflammation to adipogenesis. Sci Signal 2018; 11(527)

Rohm M, Savic D, Ball V, Curtis M K, Bonham S, Fischer R, Legrave N, MacRae J I, Tyler D J, Ashcroft F M: Cardiac Dysfunction and Metabolic Inflexibility in a Mouse Model of Diabetes Without Dyslipidaemia. Diabetes 2018; 1057-1067

Lehmann L H, Jebessa ZmH, Kreusser M M, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth A H, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer S W, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier L S, Londoño J E C, Meder B, Freichel M, Gröne H J, Most P, Müller O J, Herzig S, Furlong E E M, Katus H A, Backs J: A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway. Nat Med 2018; 24(1):62-72

Molatore S, Kügler A, Irmler M, Wiedemann T, Neff F, Feuchtinger A, Beckers J, Robledo M, Roncaroli F, Pellegata N S : Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: a novel model of invasive medullary thyroid carcinoma. Endocr Relat Cancer 2018; 25(2):145-162

Schosserer M, Grillari J, Wolfrum C, Scheideler M: Age-induced changes in white, brite, and brown adipose depots. Gerontology 2018; 64(3):229-236

Zemva J, Pfaff D, Groener J B, Fleming T, Herzig S, Teleman A, Nawroth P , Tyedmers J: Effects of the reactive metabolite Methylglyoxal on cellular signalling, Insulin action and metabolism – what we know in mammals and what we can learn from yeast. Exp Clin Endocrinol Diabetes 2018; doi:10.1055/s-0043-122382

Andersen S T, Witte D R, Dalsgaard E, Andersen H, Nawroth P P, Fleming T, Jensen T M, Finnerup N B, Jensen T S, Lauritzen T, Feldman E L, Callaghan B C, Charles M: Risk factors for incident diabetic polyneuropathy in a cohort with screen-detected type 2 diabetes followed for 13 years: Addition-Denmark. Diabetes Care 2018; 41, 1068-1075

Jende J M E, Groener J B, Oikonomou D, Heiland S, Kopf S, Pham M, Nawroth P P, Bendszus M, Kurz F T: Diabetic neuropathy differs between type 1 and type 2 diabetes: Insights from magnetic resonance neurography. Ann Neurol 2018: 83, 588-598

Kopf S, Groener J B, Kender Z, Fleming T, Brune M, Riedinger C, Volk N, Herpel E, Pesta D, Szendroedi J, Wielpuetz M O, Kauczor H U, Katus H A, Kreuter M, Nawroth P P: Breathlessness and Restrictive Lung Disease: An Important Diabetes-Related Feature in Patients with Type 2 Diabetes. Respiration 2018; 96, 29-40

Kopf S, Nawroth P P:Diabetic pulmopathy: A new clinical challenge for diabetology. Exp Clin Endocrinol Diabet 2018: 126, 590-591

Kopf S, Nawroth P P: Dicarbonyl compounds affect cardiovascular mortality in type 2 diabetes comment. Diabetol Stoffwechs 2018: 13, 394-395

Mendler M, Kopf S, Groener J B, Riedinger C, Fleming T H, Nawroth P P, Okun J G: Urine levels of 5-aminoimidazole-4-carboxamide riboside (AICAR) in patients with type 2 diabetes. Acta Diabetol 2018; 55, 585-592

Moraru A, Wiederstein J, Pfaff D, Fleming T, Miller A K, Nawroth P P, Teleman A A: Elevated levels of the reactive metabolite methylglyoxal recapitulate progression of type 2 diabetes. Cell Metab 2018; 27, 926-934.e8

Rezende F, Moll F, Walter M, Helfinger V, Hahner F, Janetzko P, Ringel C, Weigert A, Fleming I, Weissmann N, Kuenne C, Looso M, Rieger M A, Nawroth P P, Fleming T, Brandes R P, Schröder K: The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice. Redox Biol 2018; 15, 12-21

Sachdeva R, Schlotterer A, Schumacher D, Matka C, Mathar I, Dietrich N, Medert R, Kriebs U, Lin J, Nawroth P P, Birnbaumer L, Fleming T, Hammes H P, Freichel M: TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation. Mol Metab 2018; 9, 156-167

Schmitt F C F, Salgado E, Friebe J, Schmoch T, Uhle F, Fleming T, Zemva J, Kihm L, Nusshag C, Morath C, Zeier M, Bruckner T, Mehrabi A, Nawroth P P, Weigand M A, Hofer S, Brenner T: Cell cycle arrest and cell death correlate with the extent of ischaemia and reperfusion injury in patients following kidney transplantation – results of an observational pilot study. Transpl Int 2018; 31, 751-760

Schumacher D, Morgenstern J, Oguchi Y, Volk N, Kopf S, Groener J B, Nawroth P P, Fleming T H, Freichel M: Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes. Mol Metab 2018: 18, 143-152

Senyilmaz-Tiebe D, Pfaff D H, Virtue S, Schwarz K V, Fleming T, Altamura S, Muckenthaler M U, Okun J G, Vidal-Puig A, Nawroth P P, Teleman A A: Dietary stearic acid regulates mitochondria in vivo in humans. Nat Commun 2018; 9:3129

Weigand T, Singler B, Fleming T, Nawroth P P, Klika K D., Thiel C, Baelde H, Garbade S F, Wagner A H, Hecker M, Yard B A., Amberger A, Zschocke J, Schmitt C P, Peters V: Carnosine catalyzes the formation of the oligo/polymeric products of methylglyoxal. Cell Physiol Biochem 2018: 46, 713-726

Werner J, Herzig S: Paraneoplastic syndromes in pancreatic cancer. Pancreatic Cancer 2018; 633-657

Wiedenmann T, Dietrich N, Fleming T, Altamura S, Deelman L E, Henning R H, Muckenthaler M U, Nawroth P P, Hammes H P, Wagner A H, Hecker M: Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice. J Diab Complic 2018; 32, 130-138

Idrizaj E, Garella R, Castellini G, Mohr H, Pellegata N S, Francini F, Ricca V, Squecco R, Baccari M C: Adiponectin affects the mechanical responses in strips from the mouse gastric fundus. World J Gastroenterol 2018; 24, 4028-4035

2017

Duteil D, Tosic M, Willmann D, Georgiadi A, Kanouni T, Schuele R: Lsd1 prevents age-programed loss of beige adipocytes. Proc Natl Acad Sci USA 2017; 114(20):5265-5270

Mohr H, Pellegata N S: Animal models of MEN1. Endocr Relat Cancer 2017; T161-T177

Giroud M, Scheideler M: Long non-coding RNAs in metabolic organs and energy homeostasis. Int J Mol Sciences 2017; 18(12)

Rios Garcia M, Steinbauer B, Kshitij S, Singhal M, Mattijssen F, Maida A, Christian S,  Hess-Stumpp H, Augustin H G, Müller-Decker K, Nawroth P P, Herzig S, Berriel Diaz M: Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence. Cell Metab 2017; 26(6):842-855.e5

Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall M A, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Häring H U, Biswas S K, Reynolds P R, Hammes H P, Peperkok R, Angel P,  Herzig S, Nawroth P P: Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair. Nucleic Acids Res 2017; 45(18):10595-10613.

Scheideler M, Herzig S, Georgiadi A: Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes. Horm Mol Biol Clin Investig 2017; 31(2)

Niopek K, Üstünel B E, Seitz S, Sakurai M, Zota A, Mattijssen F, Wang X, Sijmonsma T, Feuchter Y, Gail A M, Leuchs B, Niopek D, Staufer O, Brune M, Sticht C, Gretz N, Müller-Decker K, Hammes H-P, Nawroth P, Fleming T,  Conkright M D, Blüher M, Zeigerer A, Herzig S, Berriel Diaz M: A hepatic GAbp-AMPK axis links inflammatory signaling to systemic vascular damage. Cell Rep 2017; 20(6):1422-1434

Maida A,  Chan J, Sjøberg K A, Zota A, Schmoll D, Kiens B, Herzig S, Rose A J: Repletion of branched chain amino acids reverses mTORC1 signalling but not improved metabolism during dietary protein dilution. Mol Metab 2017; 6(8):873-881

Amri EZ, Scheideler M: Small non-coding RNAs in adipocyte biology and obesity. Mol Cell Endocrinol 2017; 456:87-94

Zemva J, Fink C A, Fleming T H, Schmidt L, Loft A, Herzig S, Knieß R A, Mayer M, Bukau B, Nawroth P P, Tyedmers J: Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux. Redox Biol 2017; 13:674-686

Fischer K, Ruiz H H, Jhun K, Finan B, van der Heide V, Kalinovich A, Petrovic N, Wolf Y, Clemmensen C, Shin A C, Divanovic S, Brombacher F, Glasmacher E, Keipert S, Jastroch M, Nagler J, Schramm K W, Medrikova D, Collden G, Woods S C, Herzig S, Homann D, Jung S, Nedergaard J, Cannon B, Tschöp M H, Müller T D, Buettner C: Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis. Nat Med 2017;  23(5):623-630

Khan A, Dellago H, Karbiener M, Weilner S, Hildner F, Kantner V, Terlecki-Zaniewicz L, Gabriel C, Mück C, Jansen-Dürr P, Scheideler M, Grillari-Voglauer R, Schosserer M, Grillari J: SNEV(hPrp19/hPso4) regulates adipogenesis of human adipose stromal cells. Stem Cell Reports 2017; 8(1):21-29

Lauinger L, Li J, Shostak A, Cemel I A,    Ha N, Zhang Y, Merkl P E, Obermeyer S, Stankovic-Valentin N, Schafmeier T, Wever W J, Bowers A A, Carter K P, Palmer A E, Tschochner H, Melchior F, Deshaies R J, Brunner M, Diernfellner A: Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases. Nat Chem Biol 2017; 13(7):709-714

Vegiopoulos A, Rohm M, Herzig S: Adipose Tissue: Between the Extremes. EMBO J 2017; 36(14):1999-2017

Scheideler M, Herzig S: Let`s burn whatever you have: Mitofusin 2 metabolically re-wires brown adipose tissue. EMBO Rep 2017; 18(7):1039-1040

Sulaja A, Kopfa S, Gröneb E, Gröneb HJ, Hoffmannc S, Schleicherd E, Häringd H U, Schwengerf V, Herzig S, Flemingab T: ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy. J Diabetes  Complications 2017; 31, 1058–106

Brings S, Fleming T, Freichel M, Muckenthaler MU, Herzig S, Nawroth P P: Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention. Int J Mol Sci 2017; 18(5)

Metzendorf C, Zeigerer A, Seifert S, Sparla R, Najafi B, Canonne-Hergaux F, Zerial M, Muckenthaler M: Acute loss of the hepatic endo-lysosomal system in vivo causes compensatory changes in iron homeostasis. Sci Rep 2017; 7(1):4023

Rostomyan L, Adrian F D, Pellegata N S, Potorac I, Betea D, Castermans E, Christ E, Beckers A: Long-term management of resistant acromegaly with pasireotide LAR in 2 cases with a familial AIP mutation. Acta Clin Bel 2017: 72, 16-17

2016

Ghandour R A, Giroud M, Vegiopoulos A, Herzig S, Ailhaud G, Amri E Z, Pisani D F: IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin. Biochim Biophys Acta 2016; 1861, 285-293

Klanert G, Jadhav V, Shanmukam V, Diendorfer A, Karbiener M, Scheideler M, Bort JH, Grillari J, Hackl M, Borth N: A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines. J Biotechnol 2016; 235, 150-161

Wortmann M, Hakimi M, Fleming T, Peters A S, Sijmonsma T P, Herzig S, Nawroth P P, Böckler D, Dihlmann S: A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice. J Diabetes Res 2016; 2981639

Fujikawa Y, Roma L P, Sobotta M C, Rose A J, Diaz M B, Locatelli G, Breckwoldt M O, Misgeld T, Kerschensteiner M, Herzig S, Müller-Decker K, Dick T P: Mouse redox histology using genetically encoded probes. Sci Signal 2016; 9(419):rs1

Fuhrmeister J, Zota A, Sijmonsma T P, Seibert O, Cıngır S, Schmidt K, Vallon N,de Guia R M, Niopek K, Berriel Diaz M, Maida A, Blüher M, Okun J G, Herzig S, Rose A J: Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health. EMBO Mol Med 2016; 8, 654-669

Hatzl S, Geiger O, Kuepper M K, Caraffini V, Seime T, Furlan T, Nussbaumer E, Wieser R, Pichler M, Scheideler M, Nowek K, Jongen-Lavrencic M, Quehenberger F, Wölfler A, Troppmair J, Sill H, Zebisch A: Increased expression of miR-23a mediates a loss of expression in the RAF kinase inhibitor protein RKIP. Cancer Res 2016; 76(12), 3644-3654

Gautheron J, Vucur M, Schneider A T, Severi I, Roderburg C, Roy S, Bartneck M, Schrammen P, Berriel Diaz M, Ehling J, Gremse F, Heymann F, Koppe C, Lammers T, Kiessling F, Van Best N, Pabst O, Courtois G, Linkermann A, Krautwald S, Neumann U,Tacke F, Trautwein C, Green D, Longerich T, Frey N, Luedde M, Blüher M, Herzig S, Heikenwalder M, Luedde T: The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance. Nat. Commun 2016; 7:11869

Wiedemann T, Peitzsch M, Qin N, Neff F, Ehrhart-Bornstein M, Eisenhofer G, Pellegata N S: Morphology, biochemistry and pathophysiology of MENX-related pheochromocytoma recapitulate the clinical features. Endocrinol 2016; 3157-3166

Giroud M, Karbiener M, Pisani D F, Ghandour R A, Beranger G E, Niemi T, Taittonen M, Nuutila P, Virtanen K A, Langin D, Scheideler M, Amri E Z: Let-7i-5p represses brite adipocyte function in mice and humans. Sci Rep 2016; 6:28613

Stahl V, Maier F, Freitag M T, Floca R O, Berger M C, Umathum R, Berriel Diaz M, Herzig S, Weber M A, Dimitrakopoulou-Strauss A, Rink K, Bachert P, Ladd M E, Nagel A M: In vivo Assessment of Cold Stimulation Effects on the Fat Fraction of Brown Adipose Tissue Using DIXON MRI. J Magn Reson Imaging 2016; 45(2):369-380

Maida A, Zota A, Sjøberg K A, Sijmonsma T P, Pfenninger A, Christensen M M, Schmidt K, Fuhrmeister J, Rothermell U, Okun J G., Schmoll D, Kiens B, Herzig S, Rose A J: A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution. J Clin Invest 2016; 126, 3263-3278

Hernández H I, Fleming T, Eckstein V, Herzig S, Nawroth P P, Tyedmers J: Characterization of Aggregate Load & Pattern in living Yeast Cells by Flow Cytometry. BioTech J 2016; 61(3):137-48

Higareda-Almaraz J C, Ruiz-Moreno J S, Klimentova J , Barbieri D, Salvador-Gallego R, Ly R, Valtierra-Gutierrez I A, Dinsart C, Rabinovich G A, Stulik J , Rösl F, Rincon-Orozco B: Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment. BMC Cancer 2016; 16:680

Rohm M, Schäfer M, Laurent V, Ekim Üstünel B, Niopek K, Algire C, Hautzinger O, Sijmonsma T P, Zota A, Medrikova D, Pellegata N S, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri E Z, Kemp B E, Steinberg G R, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S: An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. Nat Med 2016; 22, 1120-1130

Giroud M, Pisani D F, Karbiener M, Barquissau V, Ghandour R A, Tews D, Fischer-Posovszky P, Chambard J C, Knippschild U, Niemi T, Taittonen M, Nuutila P, Wabitsch M, Herzig S, Virtanen K A, Langin D, Scheideler M, Amri EZ: miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function. Mol Metab 2016; 5(8):615-25

Mendler M, Riedinger C, Schlotterer A, Volk N, Fleming T, Herzig H, Nawroth P P, Morcos M: Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan. J Diabetes Comp 2016; 31(2):304-310

Lee M, Minaskan N, Wiedemann T, Irmler M, Backers J, Yousefi B H, Kaissis G, Braren R, Laitinen I, Pellegata N S: Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo. Endocr Relat Cancer 2016; 24(1):1-15

Ekim Üstünel B, Friedrich K, Maida A, Wang X,- Krones-Herzig A, Seibert O, Sommerfeld A, Jones A, Sijmonsma T P, Sticht C, Gretz N, Fleming T, Nawroth P P, Stremmel W, Rose A J, Berriel-Diaz M, Blüher M, Herzig S: Control of diabetic hyperglycaemia and insulin resistance through TSC22D4. Nat Commun 2016; 7:13267

Pehserl A, Ress A, Stanzer S, Resel M, Karbiener M, Stadelmeyer E, Stiegelbauer V, Gerger A, Mayr C, Scheideler M, Hutterer GC, Bauernhofer T, Kiesslich T, Picher M: Comprehensive analysis of miRNome alterations in response to sorafenib treatment in colorectal cancer cells. Int J Mol Sci 2016; 17(12) 2011:1-12.

Khan A, Dellago H, Karbiener M, Weilner S, Hildner F, Kantner V, Terlecki-Zaniewicz L, Gabriel C, Mück C, Jansen-Dürr P, Scheideler M, Grillari-Voglauer R, Schosserer M, Grillari J: SNEV(hPrp19/hPso4) regulates adipogenesis of human adipose stromal cells. Stem Cell Rep 2016; 8(1):21-29

Scheideler M: MicroRNAs in adipocyte formation and obesity. Best Pract Res Clin Endocrinol Metab 2016; 30(5):653-664

Zeigerer A, Wuttke A, Marsico G, Seifert S, Kaladzidis Y, Zerial M: Functional properties of hepatocytes in vitro are coreelated with cell polarity maintenance. Exp Cell Res 2016; 350(1):242-252

Berriel Diaz M, Herzig S, Schafmeier T: Biological Mechanisms for the Effect of Obesity on Cancer Risk: Experimental Evidence. Recent Res Cancer Res 2016; 208:219-242

Morgenstern J, Fleming T, Schumacher D, Eckstein V, Freichel M, Herzig S, Nawroth P P: Loss of glyoxalase 1 induces compensatory mechanisms to achieve dicarbonyl detoxification in mammalian Schwann cells. J Biol Chem 2016; 292(8):3224-3238

Peters A S, Lercher M, Fleming T H, Nawroth P P, Bischoff M S, Dihlmann S, Blöckler D, Hakimi M: Reduced gly oxalase 1 activity in carodit artery plaques of nondiabetic patients with increased hemoglobin A1c level. J Vasc Surg 2016; 64(4):990-4

Sulaj A., Zemva J, Zech U, Woehning A, Brune M, Rudofsky G, Nawroth P P, Fleming T, von Bauer R: The effect of lifestyle intervention in obesity on the solube form of activated leukyte cell adhesion molecule. BMC Endocr Disord 2016; 16:56

Hidalgo I H, Fleming T, Eckstein V, Herzig S, Nawroth P P, Tyedmers J: Characterization of aggregate load and pattern in living yeast cells by flow cytometry. BioTechniques 2016; 61, 137-148

Bosari S, Pardi E, Pellegata N S, Lee M S, Saponaro F, Torregrossa L, Basolo F, Paltrinieri E, Zatelli M C, Materazzi G, Miccoli P, Marocci C, Cetani F: Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas. Endocrine 2016; 55(2):386-397

Richter A, Lalli E, Sass S, Pellegata N S: The role of p27 in Pheochromocytoma Development. Neuroendocrinol 2016; 103, 8-8

Wang Y, Li W, Phay J E, Shen R, Pellegata N S, Saji M, Ringel M D, de la Chapelle A, He H: Primary cell culture systems for human thyroid studies. Thyroid 2016; 26, 1131-1140

2015

Jiang Y, Rose AJ, Sijmonsma TP, Bröer A, Pfenninger A, Herzig S, Schmoll D, Bröer S: Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control. Mol Metab 2015; 4(5):406-17

Medrikova D, Sijmonsma TS, Sowodniok K, Richards DM, Delacher M, Sticht C, Gretz N., Schafmeier T., Feuerer M., and Herzig S.: Brown adipose tissue harbors a distinct sub-population of regulatory T cells. PLOS One 2015; 10(2):e0118534

Karbiener M, Scheideler M.: MicroRNAs with impact on adipose tissue inflammation in obesity. MicroRNAs and other non-coding RNAs in inflammation (current series Progress in Inflammation Research). Editor: Greene CM. Springer Int Publish Switzerland 2015; 163-184.

Karbiener M, Scheideler M.: Microarray analysis of small non-coding RNAs. Small Non-coding RNAs: Methods and Protocols (current series Methods in Molecular Biology). Editor: Springer Humana Press 2015; 1296:161-171

Gutierrez D A,Muralidhar S, Feyerabend T B, Herzig S , Rodewald H R: Hematopoietic Kit deficiency, rather than lack of mast cells, protects mice from obesity and insulin resistance. Cell Metabolism 2015; 21(5):678-91

Zeigerer A et al.: Regulation of Liver Metabolism by the Endosomal GTPase Rab5. Cell Reports 2015; 11(6):884-92

Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, Wendler S, Männle D, Hinz U; Sticht C, Muciek M, Gretz N, Rose A,  Greiner V, Hofmann T, Bauer A, Hoheisel J, Berriel Diaz M, Gaida M, Werner J, Schafmeier T, Strobel O and Herzig S: Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol Med 2015; 7(8):1048-62

Karbiener M, Glantschnig C, Pisani D F,Laurencikiene J, Dahlman I, Herzig S, Amri E Z, Scheideler M: Mesoderm specific transcript (MEST) is a negative regulator of human adipocyte differentiation. International Journal of Obesity 2015; 39(12):1733-41

Okun J G, Conway S, Schmidt K V, Schumacher J, Wang X, De Guia R, Zota A, Klement J, Seibert O, Peters A, Maida A, Herzig S, Rose A J: Molecular regulation of urea cycle function by the liver glucocorticoid receptor. Mol Metab 2015; 4(10):732-40

Bayindir I, Babaeikelishomi R, Kocanova S, Sousa S S, Lerch S, Hardt O, Wild S, Bosio A, Bystricky K, Herzig S, Vegiopoulos A: Transcriptional pathways in cPGI2-induced adipocyte progenitor activation for browning. Front Endocrinol 2015; 6:129

Cheng Y S, Seibert O, Klöting N, Dietrich A, Straßburger K, Fernandez-Veledo S, Vendrell J J, Zorzano A, Blüher M, Herzig S, Berriel Diaz M, Teleman A A: PPP2R5C couples hepatic glucose and lipid homeostasis. PLOS Genet 2015; 11(10):e1005561

Beranger G E, Djedaini M, Battaglia S, Roux C H, Scheideler M, Heymann D, Amri E Z, Pisani D F: Oxytocin reverses osteoporosis in a sex-dependent manner. Front Endocrin 2015; 11(10):e1005561

Schäfer M, Oeing C, Rohm M,Baysal-Temel E, Lehmann L H, Bauer R, Volz H C, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt M N, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus H A, Berriel Diaz M, Backs J, Herzig S: Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia. Mol Metab 2015; 5(2):67-78

2014

de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S. microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis. EMBO J., 2014 Dec 15

Gstir R, Schafferer S, Scheideler M, Misslinger M, Griehl M, Daschil N, Humpel C, Obermair GJ, Schmuckermair C, Striessnig J, Flucher BE, Hüttenhofer A. Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases. RNA, 2014 Dec;20(12):1929-43

Rohringer S, Holnthoner W, Hackl M, Weihs AM, Rünzler D, Skalicky S, Karbiener M, Scheideler M, Pröll J, Gabriel C, Schweighofer B, Gröger M, Spittler A, Grillari J, Redl H. Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells. PLoS One, 2014 Dec 11;9(12):e114806

Karbiener M, Glantschnig C, Scheideler M. Hunting the needle in the haystack: a guide to obtain biologically meaningful microRNA targets. Int J Mol Sci,. 2014 Nov 6;15(11):20266-89

Hackl M, Jadhav V, Klanert G, Karbiener M, Scheideler M, Grillari J, Borth N. Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation. J Biotechnol., 2014 Nov 20;190:76-84.

Mössenböck K, Vegiopoulos A, Rose AJ, Sijmonsma TP, Herzig S, Schafmeier T. Browning of white adipose tissue uncouples glucose uptake from insulin signaling. PLoS One, 2014 Oct 14;9(10):e110428

Diaz MB, Herzig S, Vegiopoulos A. Thermogenic adipocytes: from cells to physiology and medicine. Metabolism, 2014 Oct;63(10):1238-49

Karbiener M, Scheideler M. MicroRNA Functions in Brite/Brown Fat - Novel Perspectives towards Anti-Obesity Strategies. Comput Struct Biotechnol J., 2014 Sep 18;11(19):101-5

Pisani DF, Ghandour RA, Beranger GE, Le Faouder P, Chambard JC, Giroud M, Vegiopoulos A, Djedaini M, Bertrand-Michel J, Tauc M, Herzig S, Langin D, Ailhaud G, Duranton C, Amri EZ. The ω6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway. Mol Metab. 2014 Sep 16;3(9):834-47

Maccani A, Hackl M, Leitner C, Steinfellner W, Graf AB, Tatto NE, Karbiener M, Scheideler M, Grillari J, Mattanovich D, Kunert R, Borth N, Grabherr R, Ernst W. Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation. Appl Microbiol Biotechnol., 2014 Sep;98(17):7535-48

Mattijssen F, Georgiadi A, Andasarie T, Szalowska E, Zota A, Krones-Herzig A, Heier C, Ratman D, De Bosscher K, Qi L, Zechner R, Herzig S, Kersten S. Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion. J Biol Chem., 2014 Jul 11;289(28):19279-93

Karbiener M, Pisani DF, Frontini A, Oberreiter LM, Lang E, Vegiopoulos A, Mössenböck K, Bernhardt GA, Mayr T, Hildner F, Grillari J, Ailhaud G, Herzig S, Cinti S, Amri EZ, Scheideler M. MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes. Stem Cells., 2014 Jun;32(6):1578-90

de Guia RM, Rose AJ, Herzig S. Glucocorticoid hormones and energy homeostasis. Horm Mol Biol Clin Investig. 2014 Aug;19(2):117-28.Bogorad RL, Yin H, Zeigerer A, Nonaka H, Ruda VM, Zerial M, Anderson DG, Koteliansky V. Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice. Nat Commun., 2014 May 21;5:3869

Penno CA, Morgan SA, Rose AJ, Herzig S, Lavery GG, Odermatt A. 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. Mol Metab. 2014 May 2;3(5):554-64.Deutsch AJ, Rinner B, Wenzl K, Pichler M, Troppan K, Steinbauer E, Schwarzenbacher D, Reitter S, Feichtinger J, Tierling S, Prokesch A, Scheideler M, Krogsdam A, Thallinger GG, Schaider H, Beham-Schmid C, Neumeister P. NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas. Blood, 2014 Apr 10;123(15):2367-77

Völkers M, Doroudgar S, Nguyen N, Konstandin MH, Quijada P, Din S, Ornelas L, Thuerauf DJ, Gude N, Friedrich K, Herzig S, Glembotski CC, Sussman MA. PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity. EMBO Mol Med., 2014 Jan;6(1):57-65

Jäger J, Greiner V, Strzoda D, Seibert O, Niopek K, Sijmonsma TP, Schäfer M, Jones A, De Guia R, Martignoni M, Dallinga-Thie GM, Diaz MB, Hofmann TG, Herzig S. Hepatic transforming growth factor-β 1 stimulated clone-22 D1 controls systemic cholesterol metabolism. Mol Metab., 2014 Jan 8;3(2):155-66

Eheim A, Medrikova D, Herzig S. Immune cells and metabolic dysfunction. Semin Immunopathol., 2014 Jan;36(1):13-25

2013

Fleming TH, Theilen TM, Masania J, Wunderle M, Karimi J, Vittas S, Bernauer R, Bierhaus A, Rabbani N, Thornalley PJ, Kroll J, Tyedmers J, Nawrotzki R, Herzig S, Brownlee M, Nawroth PP. Aging-dependent reduction in glyoxalase 1 delays wound healing. Gerontology., 2013;59(5):427-37

Rose AJ, Herzig S. Metabolic control through glucocorticoid hormones: an update. Mol Cell Endocrinol., 2013 Nov 5;380(1-2):65-78

Gilleron J, Querbes W, Zeigerer A, Borodovsky A, Marsico G, Schubert U, Manygoats K, Seifert S, Andree C, Stöter M, Epstein-Barash H, Zhang L, Koteliansky V, Fitzgerald K, Fava E, Bickle M, Kalaidzidis Y, Akinc A, Maier M, Zerial M. Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape. Nat Biotechnol., 2013 Jul;31(7):638-46

Rommer A, Steinleitner K, Hackl H, Schneckenleithner C, Engelmann M, Scheideler M, Vlatkovic I, Kralovics R, Cerny-Reiterer S, Valent P, Sill H, Wieser R. Overexpression of primary microRNA 221/222 in acute myeloid leukemia.
BMC Cancer., 2013 Jul 29;13:364

Dellago H, Preschitz-Kammerhofer B, Terlecki-Zaniewicz L, Schreiner C, Fortschegger K, Chang MW, Hackl M, Monteforte R, Kühnel H, Schosserer M, Gruber F, Tschachler E, Scheideler M, Grillari-Voglauer R, Grillari J, Wieser M. High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan. Aging Cell., 2013 Jun;12(3):446-58

Beranger GE, Karbiener M, Barquissau V, Pisani DF, Scheideler M, Langin D, Amri EZ. In vitro brown and "brite"/"beige" adipogenesis: human cellular models and molecular aspects. Biochim Biophys Acta., 2013 May;1831(5):905-14

Becker J, Barysch SV, Karaca S, Dittner C, Hsiao HH, Berriel Diaz M, Herzig S, Urlaub H, Melchior F. Detecting endogenous SUMO targets in mammalian cells and tissues. Nat Struct Mol Biol., 2013 Apr;20(4):525-31

Greussing R, Hackl M, Charoentong P, Pauck A, Monteforte R, Cavinato M, Hofer E, Scheideler M, Neuhaus M, Micutkova L, Mueck C, Trajanoski Z, Grillari J, Jansen-Dürr P. Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics., 2013 Apr 4;14:224

Rohm M, Sommerfeld A, Strzoda D, Jones A, Sijmonsma TP, Rudofsky G, Wolfrum C, Sticht C, Gretz N, Zeyda M, Leitner L, Nawroth PP, Stulnig TM, Diaz MB, Vegiopoulos A, Herzig S. Transcriptional cofactor TBLR1 controls lipid
mobilization in white adipose tissue. Cell Metab., 2013 Apr 2;17(4):575-85

Bach D, Fuereder J, Karbiener M, Scheideler M, Ress AL, Neureiter D, Kemmerling R, Dietze O, Wiederstein M, Berr F, Plaetzer K, Kiesslich T, Pichler M. Comprehensive analysis of alterations in the miRNome in response to photodynamic treatment. J Photochem Photobiol B., 2013 Mar 5;120:74-81

Jones A, Friedrich K, Rohm M, Schäfer M, Algire C, Kulozik P, Seibert O, Müller-Decker K, Sijmonsma T, Strzoda D, Sticht C, Gretz N, Dallinga-Thie GM, Leuchs B, Kögl M, Stremmel W, Diaz MB, Herzig S. TSC22D4 is a molecular output of hepatic wasting metabolism. EMBO Mol Med., 2013 Feb;5(2):294-308

2012

Gilleron J, Zeigerer A, Marsico G, Galvez T, Zerial M. Key role of Rab5: from endosome biogenesis to liver metabolism. Med Sci (Paris)., 2012 Dec;28(12):1041-4

Klingenspor M, Herzig S, Pfeifer A. Brown fat develops a brite future. Obes Facts, 2012;5(6):890-6

Djuric Z, Kashif M, Fleming T, Muhammad S, Piel D, von Bauer R, Bea F, Herzig S, Zeier M, Pizzi M, Isermann B, Hecker M, Schwaninger M, Bierhaus A, Nawroth PP. Targeting activation of specific NF-κB subunits prevents stress-dependent atherothrombotic gene expression. Mol Med., 2012 Dec 20;18:1375-86

Eichelbaum K, Winter M, Berriel Diaz M, Herzig S, Krijgsveld J. Selective enrichment of newly synthesized proteins for quantitative secretome analysis. Nat Biotechnol., 2012 Oct;30(10):984-90

Zeigerer A, Gilleron J, Bogorad RL, Marsico G, Nonaka H, Seifert S, Epstein-Barash H, Kuchimanchi S, Peng CG, Ruda VM, Del Conte-Zerial P, Hengstler JG, Kalaidzidis Y, Koteliansky V, Zerial M. Rab5 is necessary for the biogenesis of the endolysosomal system in vivo. Nature, 2012 May 23;485(7399):465-70

Algire C, Medrikova D, Herzig S. White and brown adipose stem cells: from signaling to clinical implications. Biochim Biophys Acta, 2013 May;1831(5):896-904

Lee AW, Hengstler H, Schwald K, Berriel-Diaz M, Loreth D, Kirsch M, Kretz O, Haas CA, de Angelis MH, Herzig S, Brümmendorf T, Klingenspor M, Rathjen FG, Rozman J, Nicholson G, Cox RD, Schäfer MK. Functional inactivation of the
genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype. PLoS One, 2012;7(7):e41537

Skreka K, Zywicki M, Karbiener M, Hüttenhofer A, Scheideler M, Rederstorff M. Expression Profiling of a Heterogeneous Population of ncRNAs Employing a Mixed DNA/LNA Microarray. J Nucleic Acids, 2012;2012:283560

Eduati F, Di Camillo B, Karbiener M, Scheideler M, Corà D, Caselle M, Toffolo G. Dynamic modeling of miRNA-mediated feed-forward loops. J Comput Biol., 2012 Feb;19(2):188-99

2011

Pisani DF, Djedaini M, Beranger GE, Elabd C, Scheideler M, Ailhaud G, Amri EZ. Differentiation of Human Adipose-Derived Stem Cells into "Brite" (Brown-in-White) Adipocytes. Front Endocrinol. (Lausanne) 2011 Nov 29;2:87.

Karbiener M, Neuhold C, Opriessnig P, Prokesch A, Bogner-Strauss JG, Scheideler M. MicroRNA-30c promotes human adipocyte differentiation and co-represses PAI-1 and ALK2. RNA Biol. 2011 Sep-Oct;8(5):850-60.

Rose AJ, Berriel Díaz M, Reimann A, Klement J, Walcher T, Krones-Herzig A, Strobel O, Werner J, Peters A, Kleyman A, Tuckermann JP, Vegiopoulos A, Herzig S. Molecular control of systemic bile acid homeostasis by the liver glucocorticoid
receptor. Cell Metab. 2011 Jul 6;14(1):123-30.

Schafmeier T, Diernfellner AC. Light input and processing in the circadian clock of Neurospora. FEBS Lett. 2011 May 20;585(10):1467-73.

Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Berriel Diaz M, Herzig S. Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia. Cell Metab. 2011 Apr 6;13(4):389-400.

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