Molecular Neurobiology

Most important publications:

Rybak-Wolf A, Stottmeister C, Glažar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Öhman M, Refojo D, Kadener S, Rajewsky N.
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.
Mol Cell. 58:870-85 (2015)

Vogl AM, Brockmann MM, Giusti SA, Maccarrone G, Vercelli CA, Bauder CA, Richter JS, Roselli F, Hafner AS, Dedic N, Wotjak CT, Vogt-Weisenhorn DM, Choquet D, Turck CW, Stein V, Deussing JM, Refojo D
Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition
Nat Neurosci 18:239-51 (2015)

Giusti SA, Vogl AM, Brockmann MM, Vercelli CA, Rein ML, Trümbach D, Wurst W, Cazalla D, Stein V, Deussing JM, Refojo D
MicroRNA-9 controls dendritic development by targeting REST
Elife 3. doi: 10.7554/eLife.02755 (2014)

Refojo D, Schweizer M, Kuehne C, Ehrenberg S, Thoeringer C, Vogl AM, Dedic N, Schumacher M, von Wolff G, Avrabos C, Touma C, Engblom C, Schütz G, Nave K-A, Eder M, Wotjak CT, Sillaber I, Holsboer F, Wurst W, Deussing JM.
Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1
Science 333:1903-1907 (2011)

Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak C, Wurst W, Deussing JM.
Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior
Mol Psychiatry 13:1028-1042 (2008)

Refojo, D., Echenique, C., Müller, M.B., Reul, J.M.H.M., Deussing, J.M., Wurst, W., Sillaber, I., Páez- Pereda, M., Holsboer, F., Arzt, E.
CRH activates ERK1/2 MAPK in specific brain areas
PNAS - Proceedings of the National Academy of Sciences 102:6183-6188 (2005)