Mouse Genetics

The IDG Mouse Genetics Group generates targeted mouse mutants for internal scientific projects and external collaborations. The High-Throughput Molecular Genetics participates in the international EUCOMM large scale mutagenesis program to create a genome-wide resource of conditional targeted ES cells and mice. Within the national DIGTOP (disease genes to proteins) project the proteomic interactions of disease-related genes in stem cells and mice are analysed. The Genetic Tools Development teams develop new mutagenesis tools and provide infrastructure and a microinjection service for the generation of mouse mutants. The Bioinformatics team develops data infrastructures for the high-throughput analysis of mouse mutants and is involved in the modelling of genetic and protein interaction networks.