Our objective is to discover, validate and target novel pathomechanisms and molecular signals for the development of personalized preventive and therapeutic strategies for diabetes, obesity and co-morbidities such as cancer and cardiovascular disease. The IDO currently comprises 14 research groups (including 4 Junior Research Groups) and the Neurobiology Research Unit headed by Dr. Pfluger. The IDO is part of the Helmholtz Diabetes Center (HDC).