Matthias Tschöp receives Laureate Award of the Endocrine Society

Neuherberg, August 25, 2016. The international Endocrine Society will honour Prof. Dr. Matthias Tschöp, Director of the Helmholtz Diabetes Center at Helmholtz Zentrum München and Chair of the Division of Metabolic Diseases at the Technische Universität München, with the 2017 Laureate Award. His scientific achievements and entrepreneurship are recognized in the category Outstanding Innovation Award.

Source: HMGU

Established in 2013, this award recognizes endocrinologists who have demonstrated innovation and entrepreneurship to further endocrine research or practice in support of the field of endocrinology, patients, and society at large. Tschöp discovered major components of endocrine gut-brain communication, based on which he developed several new clinical drug candidates for diabetes and obesity together with the chemist Richard DiMarchi.

Described in more than 300 publications, Tschöp’s pioneering work has enabled basic research discoveries to transition to clinical testing. Tschöp discovered that the gastric peptide ghrelin acts as a hormone that regulates—but is also controlled by—food intake, body weight, glucose, energy and lipid metabolism. He went on to identify neuroendocrine circuits through which ghrelin and other gut hormones govern systemic metabolism, food intake and body weight in health and disease.

This allowed him to co-discover several novel classes of unimolecular poly-agonists that reduce body weight, correct liver steatosis and improve glucose tolerance with unprecedented efficacy. With his work, Tschöp has pioneered multiple new technological as well as conceptual approaches leading to metabolic precision medicines poised to have major impact in the treatment of metabolic disorders.

Established in 1944, the Society’s Laureate Awards recognize the highest achievements in the endocrinology field, including groundbreaking research and innovations in clinical care. The Society, which is celebrating its centennial in 2016, has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries.