Astrocyte-Neuron Networks

Aim: To explore the functional role of astrocytes controlling energy metabolism at the central and peripheral level. 

  • Discover target genes in astrocytes involved in regulating energy homeostasis;
  • Characterization of astrocyte heterogeneity in the hypothalamus and its response to different diets;
  • Hormonal sensing in astrocytes in regulating neuronal circuitries involved in controlling energy expenditure and food intake;
  • The implication of mitochondrial dysfunction in astrocytes in the development of obesity.