Team Member

Dr. Andrzej Malinowski
Post Doc

Phone: +49 89 3187-49156
E-mail
Building/Room: Campus Neuherberg, building 3620, room 040a

 

Project Description

The aim of my research is to better understand the mechanisms underlying formation of the endocrine lineage in human pancreas. Specifically, I study the role of the Wnt signalling pathways in the endocrine induction of human induced pluripotent stem cells (iPSCs). To this end,  I use a combination of in vitro differentiation,  reporter cell lines, CRISPR-based screening approaches, single cell transcriptomics and microfluidics.

Academic and Research Activities

2011 - 2015PhD in Stem Cell Biology and Epigenetics , Imperial College London, UK
2007 - 2010 BSc with Honours in Cell Biology, University of Edinburgh, UK

Publications

Malinowski AR and Fisher AG. Reprogramming of Somatic Cells towards Pluripotency by Cell Fusion. Methods in Molecular Biology 1480, 289 – 299, 2016.

Landeira D*, Bagci H*, Malinowski AR*, Brown KE, Soza-Ried J, Feytout A, Webster Z, Ndjetehe E, Cantone I, Asenjo HG, Brockdorff N, Carroll T, Merkenschlager M, Fisher AG. Jarid2 coordinates Nanog expression and PCP/Wnt signalling required for efficient ESC differentiation and early embryo development. Cell Reports 12, 573 – 586 July 28, 2015. *contributed equally

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