Team Member

Dr. Anika Böttcher
Post Doc

Phone: + 49 89-3187-43150
E-mail
Building/Room: Campus Neuherberg, building 3620, room 034c

 

Understanding endocrine lineage formation and specification in gut and pancreas

 

Academic and Research Activities

since Oct. 2010 Helmholtz Zentrum Muenchen, Institute for Stem cell Research, Neuherberg, Germany
Post doc in Endoderm development group
Sept. 2005 – Sept. 2010Max Planck Institute of Biochemistry, Martinsried, Germany; Department of Molecular Medicine
PhD thesis “Dissecting the integrin-linked kinase (ILK) kinase activity in vivo” Supervisor: Prof. Dr. Reinhard Fässler
June 2004 – Aug. 2005Friedrich-Schiller University of Jena, Germany
Department of Medical Biochemistry
Diploma thesis “Adjustable expression of oligomeric Ras-Raf binding domains to block Ras-mediated cellular signalling in a reversible manner”
Supervisor: Prof. Dr. Karlheinz Friedrich
Aug. 2002 –  June 2003 University of Lund, Sweden
Graduate Studies in biology (genetics and immunology)
Sept. 1999 – Sept. 2004 Friedrich-Schiller University of Jena, Germany
Graduate studies in biology

 

Publications

Kim, M., Ogawa, M., Fujita, Y., Yoshikawa, Y., Nagai, T., Koyama, T., Nagai, S., Lange, A., Fässler, R., and Sasakawa, C. (2009a). Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. Nature 459, 578-582.

Lange, A., Wickstrom, S.A., Jakobson, M., Zent, R., Sainio, K., and Fässler, R. (2009). Integrin-linked kinase is an adaptor with essential functions during mouse development. Nature 461, 1002-1006.

Smeeton, J., Zhang, X., Bulus, N., Mernaugh, G., Lange, A., Karner, C.M., Carroll, T.J., Fässler, R., Pozzi, A., Rosenblum, N.D., et al. (2010). Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development. Development 137, 3233-3243.

Wickstrom, S.A., Lange, A., Hess, M.W., Polleux, J., Spatz, J.P., Kruger, M., Pfaller, K., Lambacher, A., Bloch, W., Mann, M., et al. (2010a). Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell 19, 574-588.

Wickstrom, S.A., Lange, A., Montanez, E., and Fässler, R. (2010b). The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! Embo J 29, 281-291.

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