Team Member

Dr. Kaiyuan Yang
Post Doc

Phone: +49 89-3187-49335
E-mail
Building/Room: Campus Neuherberg, building 3620, room 040a

 

Project Description


My project is focused on understanding:

  • the pathways and mechanisms of the development,
  • degeneration and regeneration of insulin-producing beta cells; analysis of the planar cell polarity gene Flattop
  • the influence of metabolic signal transduction on the degeneration and regeneration of beta cells

Academic and Research Activities

Sept. 2015 - Dec. 2017Postdoctoral Fellow, Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, Canada Ph.D., Nutrition and Metabolism
Sept. 2010 - Aug. 2015Ph.D., Nutrition and Metabolism, Nutrition and Metabolism,
Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, Canada
Sept. 1996 - July 2010B.Sc., Food Quality and Safety,
China Pharmaceutical University, Nanjing, China

 

Publications

Yang K, Chan CB. Proposed mechanisms of the effects of proanthocyanidins on glucose homeostasis. Nutr Rev. 2017,75(8):642-657. doi: 10.1093/nutrit/nux028.

Yang K, Chan CB. Epicatechin potentiation of glucose-stimulated insulin secretion in INS-1 cells is not dependent on antioxidant activity. Acta Pharmacol Sin/Nature. 2018. In press.

Li J, Yang K*, Ju T, Ho T, McKay CA, Gao Y, Forget SK, Gartner SR, Field CJ, Chan CB, Willing BP. Early life antibiotic exposure affects pancreatic islet development and metabolic regulation. Sci Rep. 2017,7:41778. doi: 10.1038/srep41778. *Co-first author

Yang K, Gotzmann J, Kuny S, Huang H, Sauvé Y, Chan CB. Five stages of progressive β-cell dysfunction in the laboratory Nile rat model of type 2 diabetes. J Endocrinol. 2016,229(3):343-56. doi: 10.1530/JOE-15-0517

Yang K, Hashemi Z, Han W, Jin A, Yang H, Ozga J, Li L, Chan CB. Hydrolysis enhances bioavailability of proanthocyanidin-derived metabolites and improves β-cell function in glucose intolerant rats. J Nutr Biochem. 2015,26(8):850-9. doi: 10.1016/j.jnutbio.2015.03.002.

 

 

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