Personal Details

Dr. Ingo Burtscher
Deputy Director and Group Leader Beta cell replacement and stem cell research

Phone: + 49 89-3187-2063
E-mail
Building/Room: Campus Neuherberg, building 3620, room 302c

 

Project Description

The basis of in vitro differentiations are cellular and molecular processes occurring during early embryonic development. In our group we focus on a better understanding, how these processes lead to lineage specification, growth control and maturation of pancreatic endocrine lineages in the mouse. These findings we translate in vitro into the culture dish using induced pluripotent human stem cells (hiPSC).

Our strength is the generation genetic mouse and human stem cell models including gene knock out models but also fluorescent reporter lines. These are exploited in combination with cutting edge imaging techniques as well as transcriptome analysis on a single cell level for better understanding of beta-cell biology. Our goal is to improve beta cell differentiation and function, provide platforms for disease modeling and drug screening and, as ultimate goal, help to overcome remaining hurdles for stem cell-derived beta cell replacement therapies in diabetic patients.

 

Academic and Research Activities

 

since 2012

Group leader "Beta cell replacement and stem cell research", Helmholtz Zentrum München, Institute of Diabetes and Regeneration Research, Munich, Germany

2005 - 2012Postdoctorial Research Fellow in the Group of Dr. Heiko Lickert, Endoderm Research, Stem Cell Institute, Helmholtz Zentrum Munich
Oct 2000 – Oct 2004PhD at Queen Mary & Westfield College, University of London, Group of Prof. Dean Nizetic
Title:” Characterisation of USP25, a chromosome 21 gene potentially contributing to specific features of Down syndrome, and the effects of its overexpression on cellular structures, function & behaviour
Jan. 1998 – Jun 1999Institue of Molecular Pathology, Vienna
Group of Dr. Gerhard Christofori
Diploma Thesis: “IGF-Mediated Survival Signaling in SV-40 T Antigen-mediated Tumorigenesis”
Diploma mark: Mit Auszeichnung bestanden
Feb. 1993 – Jul. 1999Studies of Biology at University of Vienna
Genetics, Biochemistry and Microbiology
Diploma overall mark: Bestanden

Publications

Publications of Ingo Burtscher at PubMed