Personal Details

Sára Bileková
PhD student - Insulin/IGF signalling in metabolism and growth

E-mail
Building/Room: Campus Neuherberg, building 3620, room 028b

 

Project description

Diabetes mellitus is characterized by chronic hyperglycemia and pancreatic β-cell dysfunction. We have identified two novel receptors in the insulin/insulin-like growth factor (Ins/IGF) pathway. I work on the in-vitro and in-vivo characterization of the novel receptors and their role in β-cell function, especially with respect to endoplasmic reticulum (ER) stress. Preventing beta cells from suffering from chronic ER stress is a promising therapeutic strategy in treating diabetes.

 Academic and research activities

Since 05/2019 – Doctoral student, Helmholtz Zentrum München, Institute of Diabetes and Regeneration Research

07/2018 – 12/2018 University of California San Francisco, Department of Biochemistry and Biophysics (Reiter Lab), Master’s thesis – “The Role of cAMP in the Hedgehog Signaling Pathway”

10/2016 – 03/2019 – Master of Science, Biochemistry, Ludwig Maximilian University of Munich

09/2013 – 06/2016 – Bachelor’s degree, Biochemistry, Comenius University in Bratislava, Slovakia

Publications

Bileková S, Sachs S, Lickert H, Pharmacological Targeting of Endoplasmic Reticulum Stress in Pancreatic Beta Cells, Trends in Pharmacological Sciences, December 2020

Awards

2019 – Runner-up Award, 1st International Helmholtz Research School for Diabetes 3-Minute Thesis (3MT®) Competition