Personal Details

Dr. Weiwei Xu
Post Doc - Insulin/IGF signalling in metabolism and growth

E-mail
Building/Room: Campus Neuherberg, building 3620, room 040a

 

Academic and Research Activities

since Jul. 2019

Postdoctoral Scientist. Institute of Diabetes and Regeneration Research. Helmholtz Zentrum München, Munich, Germany. Project: Beta-cell Differentiation and Maturation

Aug 2018 – Jun 2019

Postdoctoral Scientist. Tulane University School of Medicine. New Orleans, LA, USA. Project: The Role of Islet steroidogenesis in Pancreatic Beta Cell Function and Insulin Secretion

Aug 2013 – July 2018

Graduate Researcher. Tulane University School of Medicine. New Orleans, LA, USA. PhD thesis: Mechanisms of Androgen Receptor Stimulation of Insulin Secretion in the Male

Sep 2009 – Jun 2013

Bachelor in Veterinary Medicine. Sichuan Agricultural University. Chengdu, Sichuan, China

Publications

Xu W, Morford JJ, Mauvais-Jarvis F. Emerging role of testosterone in pancreatic β–cell function and insulin secretion. J Endocrinol. 2019 Jan 1. PMID: 30601759.

 

Zhang Y, Parajuli KR, Fava GE, Gupta R, Xu W, Nguyen LU, Zakaria AF, FonsecaVA, Wang H, Mauvais-Jarvis F, Sloop  KW,  Wu  H.  GLP-1 Receptor in Pancreatic α Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner. Diabetes. 2018 Nov 2. PMID: 30389749.

 

Allard C, Morford JJ, Xu B, Salwen B, Xu W, Desmoulins L, Zsombok A, Kim JK, Levin ER, Mauvais-Jarvis F. Loss of  Nuclear  and  Membrane  Estrogen  Receptor-αDifferentially  Impairs  Insulin  Secretion  and  Action  in  Male  and Female Mice. Diabetes. 2018 Oct 10. PMID: 30305367.

 

Navarro G, Allard C, Morford JJ, Xu  W, Liu S, Molinas AJ, Butcher SM, Fine NHF, Blandino-Rosano M, Sure VN, Yu  S,  Zhang  R,  Münzberg  H,  Jacobson  DA,  Katakam PV,  Hodson  DJ,  Bernal-Mizrachi  E,  Zsombok  A,  Mauvais-Jarvis F. Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes. JCI Insight. 2018 Jun 21.PMID: 29925687.

 

Xu  WNiu  T,  Xu  B,  Navarro  G,  Schipma  MJ,  Mauvais-Jarvis  F.  Androgen receptor-deficient islet β-cells exhibit alteration in genetic markers of insulin secretion and inflammation. A transcriptome analysis in the male mouse. J Diabetes Complications. 2017 May. PMID: 28343791.

 

Navarro  G*, Xu  W*,  Jacobson  DA,  Wicksteed  B,  Allard  C,  Zhang  G,  De  Gendt  K,  Kim  SH,  Wu  H,  Zhang  H, Verhoeven  G, Katzenellenbogen  JA,  Mauvais-Jarvis  F. Extranuclear  Actions  of  the  Androgen  Receptor  Enhance Glucose-Stimulated Insulin Secretion in the Male. Cell Metab. 2016 May 10. PMID: 27133133. *Co-first authors

 

Navarro G, Allard C, Xu W, Mauavais-Jarvis F. The role of androgens in metabolism, obesity, and diabetes in males and females. Obesity (Silver Spring). 2015 Apr 23. PMID: 25755205.

 

Liu  X,  Zhu  L,  Shi  X,  Xu  Z,  Mei  M, Xu  W,  Zhou  Y,  Guo  W,  Wang  X. Indirect-blocking  ELISA  for  detecting antibodies  against glycoprotein  B  (gB)  of porcine  cytomegalovirus  (PCMV). J  Virol Methods. 2012 Dec. PMID: 22981981.