News

23.05.2019

Review: Genome activation and architecture in the early mammalian embryo

Advances in high-throughput genomics assays have lead to significant developments in our understanding of chromatin organization in the nucleus.  In a review in Current Opinion in Genetics & Development, Natasha Jansz and Maria Elena Torres-Padilla from the Institute of Epigenetics and Stem Cells discuss recent findings on the dynamic organization of chromatin within the early embryo and highlight unanswered questions concerning the mechanisms behind this organization that will be interesting to address in the field in the future.

Original publication: Jansz N, Torres-Padilla ME (2019) Genome activation and architecture in the early mammalian embryo Current Opinion in Genetics & Development, 55, 52-58