Research

Research within the Institute of Epigenetics and Stem Cells aims at determining how stem cells originate in vivo and at establishing epigenetic principles behind changes in cellular plasticity and genome reprogramming. They study how the transitions in cell potency and cell fate are regulated by chromatin-mediated processes using a variety of approaches including quantitative imaging, modeling, functional genomics and cell biology. Understanding the molecular mechanisms behind the maintenance and manipulation of cellular plasticity will have strong implications in regenerative medicine and disease, and will help in deciphering human reproduction and infertility.

Epigenetics and cell fate in early mammalian development

Physics- and data-based modelling of cellular decision making

Microscopy Core