Prof. Dr. Rolf Holle, Quelle: privat

Prof. Dr. Rolf Holle
Ehemaliger Mitarbeiter der AG 2

Telefon: +49 89 3187-4198 (Sekretariat)

Wissenschaftlicher Werdegang:

  • Studium der Mathematik und Psychologie, Diplom in Mathematik an der Universität Marburg
  • Promotion zum Dr. biol. hom. am Fachbereich Humanmedizin der Universität Giessen
  • Habilitation für das Fach Medizinische Biometrie an der Universität Heidelberg
  • Umhabilitation an die Ludwig-Maximilians-Universität München
  • Professur (apl.) an der Medizinischen Fakultät der LMU

Fort- und Weiterbildung:

Arbeitsschwerpunkte und Forschungsinteressen:

  • Gesundheitsökonomische Evaluation im Rahmen klinischer Studien  
  • Interventions- und Beobachtungsstudien in der Versorgungsforschung
  • Methodische Aspekte der Kosten- und Nutzenmessung

Aktuelle Forschungsprojekte: 


Im Rahmen der Masterstudiengänge Public Health und Epidemiology an der LMU München:

    Blockkurs Gesundheitsökonomische Evaluation (4 Tage, SS)

    Blockkurs Outcomes Research (1 Tag, WS)

    Masterkolloqium (3 Tage, SS)

    Betreuung und Mentoring von Masterstudenten

Im Rahmen des PhD Programms International Health an der LMU München:

    Health Economics

    Betreuung von Dissertationen

Aktivitäten in Gremien und Fachgesellschaften:

  • Mitglied der GMDS, der Deutschen Region der IBS sowie der DGGÖ
  • Gutachtertätigkeit u.a. für BMBF, BMG, DFG, Alexander-von-Humboldt-Stiftung, Deutsche Krebsgesellschaft
  • Mitglied des Advisory Boards mehrerer klinischer Studien und Forschunsverbünde
  • Reviewer für zahlreiche Fachzeitschriften (u.a. Pharmacoeconomics, Medical Care, Statistics in Medicine, BMC Public Health, European Journal of Cancer, Methods of Information in Medicine, BMC Health Services Research, American Journal of Epidemiology, European Journal of Health Economics)


    • DMW Walter Siegenthaler Preis 2007 (zusammen mit  A. Icks et al.) 
    • Paula und Richard von Hertwig-Preis für interdisziplinäre Zusammenarbeit 2006 (zusammen mit A. Pfeufer et al.)



    Ulrich, L.R.* et al.: Cost-effectiveness analysis of case management for optimized antithrombotic treatment in German general practices compared to usual care - Results from the PICANT trial. Health Econ. Rev. 9:4 (2019)


    Kähm, K., Laxy, M., Schneider, U.* & Holle, R.: Exploring different strategies of assessing the economic impact of multiple diabetes-associated complications and their interactions: A large claims-based in Germany. Pharmacoeconomics 37, 63-74 (2019)


    Kowall, B.* et al.: Incidence rates of type 2 diabetes in people with impaired fasting glucose (ADA vs. WHO Criteria) and impaired glucose tolerance: Results from an older population (KORA S4/F4/FF4 Study). Diabetes Care 42, E18-E20:DC181473 (2019)


    Witt, S. et al.: Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis. Respir. Res. 20:47 (2019)


    Mühlig, Y.* et al.: Psychosoziale Charakterisierung und Integrative Versorgung arbeitsloser Jugendlicher mit extremer Adipositas – ein Modellprojekt. Psychother. Psychosom. Med. Psychol., accepted (2019)


    Karl, F., Holle, R., Schwettmann, L., Peters, A. & Laxy, M.: Status quo bias and health behavior: Findings from a cross-sectional study. Eur. J. Public Health, accepted (2019)


    Rospleszcz, S. et al.: Temporal trends in cardiovascular risk factors and performance of the Framingham Risk Score and the Pooled Cohort Equations. J. Epidemiol. Community Health 73, 19-25 (2019)


    Bächle, C.* et al.: Association of individual and area-level socioeconomic conditions with quality of life and glycaemic control in 11-to 21-year-old adolescents with early-onset type 1 diabetes: A cross-sectional study. Qual. Life Res. 27, 3131-3136 (2018)


    Qosaj, F.A.*, Froeschl, G.*, Berisha, M.*, Bellaq, B.* & Holle, R.: Catastrophic expenditures and impoverishment due to out-of-pocket health payments in Kosovo. Cost Eff. Resour. Alloc. 16:26 (2018)


    Walter, J., Holle, R., Tufman, A.* & Schwarzkopf, L.: Changes in targeted therapy and costs in NSCLC between 2009 and 2013. Eur. Respir. J. 52 (2018)


    Graf, J.* et al.: Compatibility of medication with PRISCUS criteria and identification of drug interactions in a large cohort of patients with COPD. Pulm. Pharmacol. Ther. 49, 123-129 (2018)


    Kurz, C.F. & Holle, R.: Demand for medical care by the elderly: A nonparametric variational Bayesian mixture approach. OASIcs 4, 4:1-4:7 (2018)


    Steinbeisser, K., Grill, E.*, Holle, R., Peters, A. & Seidl, H.: Determinants for utilization and transitions of long-term care in adults 65+in Germany: Results from the longitudinal KORA-Age study. BMC Geriatr. 18:172 (2018)


    Krack, G. et al.: Determinants of adherence and effects on health-related quality of life after myocardial infarction: A prospective cohort study. BMC Geriatr. 18:136 (2018)


    Kähm, K., Holle, R. & Laxy, M.: Diabetes mellitus: Kosten von Komplikationen erstmals detailliert berechnet. Dtsch. Ärztebl. 115:14 (2018)


    Karl, F. et al.: Direct healthcare costs associated with device assessed and self-reported physical activity: Results from a cross-sectional population-based study. BMC Public Health 18:966 (2018)


    Lennerz, B.S.* et al.: Do adolescents with extreme obesity differ according to previous treatment seeking behavior? The Youth with Extreme obesity Study (YES) cohort. Int. J. Obes., accepted (2018)


    Kähm, K. et al.: Health care costs associated with incident complications in patients with type 2 diabetes in Germany. Diabetes Care 41, 971-978 (2018)


    Karrasch, S. et al.: Heterogeneous pattern of differences in respiratory parameters between elderly with either good or poor FEV1. BMC Pulm. Med. 18:27 (2018)


    Byng, D. et al.: Identifying predictors of healthcare utilization and costs in COPD patients over 18 months: First longitudinal results of the COSYCONET cohort. Eur. Respir. J. 52 (2018)


    Rost, S. et al.: New indexes of body fat distribution and sex-specific risk of total and cause-specific mortality: A prospective cohort study. BMC Public Health 18:427 (2018)


    Grill, E.* et al.: Prevalence, determinants, and consequences of vestibular hypofunction. Results from the KORA-FF4 survey. Front. Neurol. 9, 1076:1076 (2018)


    Bächle, C.* et al.: Regional differences in antihyperglycemic medication are not explained by individual socioeconomic status, regional deprivation, and regional health care services. Observational results from the German DIAB-CORE consortium. PLoS ONE 13:e0191559 (2018)


    Walter, J., Tufman, A.*, Leidl, R., Holle, R. & Schwarzkopf, L.: Rural versus urban differences in end-of-life care for lung cancer patients in Germany. Support Care Cancer 26, 2275-2283 (2018)


    Laxy, M., Teuner, C.M., Holle, R. & Kurz, C.F.: The association between BMI and health-related quality of life in the US population: Sex, age and ethnicity matters. Int. J. Obes. 42, 318-326 (2018)


    Karl, F., Holle, R., Schwettmann, L., Peters, A. & Laxy, M.: Time preference, outcome expectancy, and self-management in patients with type 2 diabetes. Patient pre. adh. 12, 1937-1945 (2018)


    Icks, A.* et al.: Time spent on self-management by people with diabetes: Results from the population-based KORA survey in Germany. Diabetic Med., accepted (2018)


    Thiele, I. et al.: Time trends in stroke incidence and in prevalence of risk factors in Southern Germany, 1989 to 2008/09. Sci. Rep. 8:11981 (2018)


    Heuberger, M.* et al.: Usability of the video head impulse test: Lessons from the population-based prospective KORA study. Front. Neurol. 9:659 (2018)


    Stephan, A.J.*, Strobl, R.*, Holle, R. & Grill, E.*: Wealth and occupation determine health deficit accumulation onset in Europe - Results from the SHARE study. Exp. Gerontol. 113, 74-79 (2018)


    Mühlig, Y.* et al.: A structured, manual-based low-level intervention vs. treatment as usual evaluated in a randomized controlled trial for adolescents with extreme obesity - the STEREO trial. Obes. Facts 10, 341-352 (2017)


    Luzak, A. et al.: Association of physical activity with lung function in lung-healthy German adults: Results from the KORA FF4 study. BMC Pulm. Med. 17:215 (2017)


    Walter, J., Tufman, A.*, Holle, R. & Schwarzkopf, L.: Comparison of costs and care of lung cancer patient at the end-of-life in Germany depending on the tome of survival after diagnosis. Value Health 20, A511-A511 (2017)


    Karl, F. et al.: Costs and health-related quality of life in Alpha-1-antitrypsin deficient COPD patients. Respir. Res. 18:60 (2017)


    Schwarzkopf, L., Holle, R. & Schunk, M.: Effects of nursing home residency on diabetes care in individuals with dementia: An explorative analysis based on German claims data. Dement. Geriatr. Cogn. Disord. 7, 41-51 (2017)


    Islam, S.M.S.* et al.: Healthcare use and expenditure for diabetes in Bangladesh. BMJ Glob. Health 2:e000033 (2017)


    Schunk, M. et al.: Longitudinal change in health-related quality of life in people with prevalent and incident type 2 diabetes compared to diabetes-free controls. PLoS ONE 12:e0176895 (2017)


    Stephan, A.J.* et al.: Male sex and poverty predict abrupt health decline: Deficit accumulation patterns and trajectories in the KORA-Age cohort study. Prev. Med. 102, 31-38 (2017)


    Lennerz, B.* et al.: Medical and psychosocial implications of adoelscent extreme obesity- acceptance and effects of structured care program - Yes Study. A consortium of the BMBF. Horm. Res. Paediatr. 88, 161-161 (2017)


    Kowall, B.* et al.: Perceived risk of diabetes seriously underestimates actual diabetes risk: The KORA FF4 study. PLoS ONE 12:e0171152 (2017)


    Houben-Wilke, S.* et al.: Peripheral artery disease and its clinical relevance in patients with chronic obstructive pulmonary disease in the COPD and systemic consequences-comorbidities network study. Am. J. Respir. Crit. Care Med. 195, 189-197 (2017)


    Kahnert, K.* et al.: Relationship of hyperlipidemia to comorbidities and lung function in COPD: Results of the COSYCONET cohort. PLoS ONE 12:e0177501 (2017)


    Seidl, H. et al.: The 3-year cost-effectiveness of a nurse-based case management versus usual care for elderly patients with myocardial infarction: Results from the KORINNA follow-up study. Value Health 20, 441-450 (2017)


    Wacker, M. et al.: The contribution of symptoms and comorbidities to the economic impact of COPD: An analysis of the German COSYCONET cohort. Int. J. Chron. Obstruct. Pulmon. Dis. 12, 3437-3448 (2017)


    Rabel, M.*, Meisinger, C., Peters, A., Holle, R. & Laxy, M.: The longitudinal association between change in physical activity, weight, and health-related quality of life: Results from the population-based KORA S4/F4/FF4 cohort study. PLoS ONE 12:e0185205 (2017)


    Laxy, M. et al.: The non-linear relationship between BMI and health care costs and the resulting cost fraction attributable to obesity. Int. J. Environ. Res. Public Health 14:984 (2017)


    Kahnert, K.* et al.: Transfer factor for carbon monoxide in patients with COPD and diabetes: Results from the German COSYCONET cohort. Respir. Res. 18:14 (2017)


    Kahnert, K.* et al.: Transfer factor for carbon monoxide in patients with COPD and diabetes: Results from the German Cosyconet Cohort. Am. J. Respir. Crit. Care Med. 195 (2017)


    Stephan, A.J.* et al.: A high level of household physical activity compensates for lack of leisure time physical activity with regard to deficit accumulation: Results from the study KORA-Age. Prev. Med. 86, 64-69 (2016)


    Wacker, M. et al.: Assessing health-related quality of life in COPD: Comparing generic and disease-specific instruments with focus on comorbidities. BMC Pulm. Med. 16:70 (2016)


    Wolf, K. et al.: Association between long-term exposure to air pollution and biomarkers related to insulin resistance, subclinical inflammation and adipokines. Diabetes 65, 3314-3326 (2016)


    Riedl, A. et al.: Comparison of different measures of obesity in their association with health-related quality of life in older adults - results from the KORA-Age study. Public Health Nutr. 19, 3276-3286 (2016)


    Yousri, N.A.* et al.: Diagnostic and prognostic metabolites identified for joint symptoms in the KORA population. J. Proteome Res. 15, 554-562 (2016)


    Wacker, M. et al.: Direct and indirect costs of COPD and its comorbidities: Results from the German COSYCONET study. Respir. Med. 111, 39-46 (2016)


    Chen, B.H.* et al.: DNA methylation-based measures of biological age: Meta-analysis predicting time to death. Aging 8, 1844-1865 (2016)


    Wacker, M.E. et al.: How do symptoms and comorbidities affect healthcare costs in patients with COPD? Results from the new German cosyconet cohort. Am. J. Respir. Crit. Care Med. 193 (2016)


    Olden, M.*, Holle, R., Heid, I.* & Stark, K.*: IDGenerator: Unique identifier generator for epidemiologic or clinical studies. BMC Med. Res. Methodol. 16:120 (2016)


    Shariful Islam, S.M.* et al.: Mobile phone use and willingness to pay for SMS for diabetes in Bangladesh. J. Public Health 38, 163-169 (2016)


    Laxy, M. et al.: Quality of diabetes care in Germany improved from 2000 to 2007 to 2014, but improvements diminished since 2007. Evidence from the population-based KORA Studies. PLoS ONE 11:e0164704 (2016)


    Wacker, M. et al.: Relative impact of COPD and comorbidities on generic health-related quality of life: A pooled analysis of the COSYCONET patient cohort and control subjects from the KORA and SHIP studies. Respir. Res. 17:81 (2016)


    Herzog, B.* et al.: Socioeconomic status and anthropometric changes - a meta-analytic approach from seven German cohorts. Obesity 24, 710-718 (2016)


    Lucke, T.* et al.: Systematic analysis of self-reported comorbidities in large cohort studies - A novel stepwise approach by evaluation of medication. PLoS ONE 11:e0163408 (2016)


    Ulrich, S. et al.: The cost burden of type 2 diabetes in Germany – Results from the population-based KORA Studies. BMJ Open 6:e012527 (2016)


    Yates, N. et al.: The economic burden of obesity in Germany: Results from the population-based KORA studies. Obes. Facts 9, 397-409 (2016)


    Karch, A.* et al.: The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline. Respir. Med. 114, 27-37 (2016)


    Safita, N. et al.: The impact of type 2 diabetes on health related quality of life in Bangladesh: Results from a matched study comparing treated cases with non-diabetic controls. Health Qual. Life Outcomes 14:129 (2016)


    Seidl, H. et al.: Validity of self-reported hospital admissions in clinical trials depends on recall period length and individual characteristics. J. Eval. Clin. Pract. 22, 446-454 (2016)


    Karrasch, S. et al.: What is the impact of different spirometric criteria on the prevalence of spirometrically defined COPD and its comorbidities? Results from the population-based KORA study. Int. J. Chron. Obstruct. Pulmon. Dis. 11, 1881-1894 (2016)


    Grau, H.*, Berth, H.*, Lauterberg, J.*, Holle, R. & Gräßel, E.*: „Zuhause geht es nicht mehr“ – Gründe für den Wechsel ins Pflegeheim bei Demenz. Gesundheitswesen 78, 510-513 (2015)


    Teuner, C.M., John, J., Wolfenstetter, S.B. & Holle, R.: An economic perspective on childhood obesity. Pediatr. Adolesc. Med. 19, 148-159 (2015)


    Schwarzkopf, L., Wacker, M., Leidl, R., Huber, R.M. & Holle, R.: Analyse der Versorgungssitutation von Lungenkrebspatienten anhand von GKV-Routinedaten. Pneumologie 69, P88 (2015)


    Wolf, K. et al.: Associations between short-term exposure to particulate matter and ultrafine particles and myocardial infarction in Augsburg, Germany. Int. J. Hyg. Environ. Health 218, 535-542 (2015)


    Rückert, I.-M. et al.: Blood pressure control has improved in people with and without type 2 diabetes but remains suboptimal: A longitudinal study based on the German DIAB-CORE consortium. PLoS ONE 10:e0133493 (2015)


    Schwarzkopf, L. et al.: Cost-components of lung cancer care within the first three years after initial diagnosis in context of different treatment regimens. Lung Cancer 90, 274-280 (2015)


    Seidl, H. et al.: Cost-effectiveness of nurse-based case management versus usual care for elderly patients with myocardial infarction: Results from the KORINNA study. Eur. J. Health Econ. 16, 671-681 (2015)


    Holle, R. et al.: Do comorbidities have a specific impact on generic Health-Related Quality of Life (HRQL) in COPD patients compared to controls? First results of the German COSYCONET cohort study. Am. J. Respir. Crit. Care Med. 191:A6207 (2015)


    Hunger, M. et al.: Does nurse-based case management for aged myocardial infarction patients improve risk factors, physical functioning and mental health? The KORINNA trial. Eur. J. Prev. Cardiol. 22, 442-450 (2015)


    Kirchberger, I. et al.: Effects of a 3-year nurse-based case management in aged patients with acute myocardial infarction on rehospitalisation, mortality, risk factors, physical functioning and mental health. A secondary analysis of the randomized controlled KORINNA study. PLoS ONE 10:e0116693 (2015)


    Bock, J.O.* et al.: Ermittlung standardisierter Bewertungssätze aus gesellschaftlicher Perspektive für die gesundheitsökonomische Evaluation. Gesundheitswesen 77, 53-61 (2015)


    Seidl, H. et al.: FIMA – Fragebogen zur Erhebung von Gesundheitsleistungen im Alter: Entwicklung und Pilotstudie. Gesundheitswesen 77, 46-52 (2015)


    Schunk, M. et al.: Health-related quality of life in women and men with type 2 diabetes: A comparison across treatment groups. J. Diab. Complic. 29, 203-211 (2015)


    Wilke, S.* et al.: Impact of peripheral artery disease on functional capacity and health status in patients with chronic obstructive pulmonary disease: Results of the COSYCONET study. Am. J. Respir. Crit. Care Med. 191:A6204 (2015)


    Ziegler, D.* et al.: Increased prevalence of cardiac autonomic dysfunction at different degrees of glucose intolerance in the general population: The KORA S4 survey. Diabetologia 58, 1118-1128 (2015)


    Herder, C.* et al.: Low serum omentin levels in the elderly population with type 2 diabetes and polyneuropathy. Diabetic Med. 32, 1479-1483 (2015)


    Vogt, S. et al.: Neighborhood and healthy aging in a German city: Distances to green space and senior service centers and their associations with physical constitution, disability, and health-related quality of life. Eur. J. Ageing 12, 273-283 (2015)


    Bock, J.-O.* et al.: Standardisierte Bewertungssätze aus gesellschaftlicher Perspektive für die gesundheitsökonomische Evaluation. Baden-Baden: Nomos, 2015. 79 S.


    Peyrot, W.J.* et al.: The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Mol. Psychiatry 20, 735-743 (2015)


    Idler, N. et al.: The association between physical activity and healthcare costs in children - results from the GINIplus and LISAplus cohort studies. BMC Public Health 15:437 (2015)


    Laxy, M. et al.: The burden of diabetes mellitus in patients with coronary heart disease: A methodological approach to assess quality-adjusted life-years based on individual-level longitudinal survey data. Value Health 18, 969-976 (2015)


    Laxy, M. et al.: The effectiveness of German Disease Management Programs (DMPs) in patients with type 2 diabetes mellitus and coronary heart disease: Results from an observational longitudinal study. Diabetol. Metab. Syndr. 7:77 (2015)


    Becker, C., Holle, R. & Stollenwerk, B.: The excess health care costs of KardioPro, an integrated care program for coronary heart disease prevention. Health Policy 119, 778-786 (2015)


    Soellner, R.*, Reder, M.*, Machmer, A.*, Holle, R. & Wilz, G.*: The Tele.TAnDem intervention: Study protocol for a psychotherapeutic intervention for family caregivers of people with dementia. BMC Nurs. 14, 11 (2015)


    Schunk, M., Stark, R.G., Reitmeir, P., Meisinger, C. & Holle, R.: Towards patient-oriented diabetes care: Results from two KORA surveys in Southern Germany: J. Diabetes Res. 2015:368570 (2015)


    Wacker, M. et al.: Work absenteeism and healthcare utilization in COPD: The clinical cohort COSYCONET compared with population-based controls. Am. J. Respir. Crit. Care Med. 191:A2310 (2015)


    de Jong, T.M.* et al.: SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis. J. Clin. Periodontol. 41, 531-540 (2014)


    Bauer, K., Schwarzkopf, L., Graessel, E.* & Holle, R.: A claims data-based comparison of comorbidity in individuals with and without dementia. BMC Geriatr. 14:10 (2014)


    Maier, W. et al.: Area level deprivation is an independent determinant of prevalent type 2 diabetes and obesity at the national level in Germany. Results from the national telephone health interview surveys 'German Health Update' GEDA 2009 and 2010. PLoS ONE 9:e89661 (2014)


    Hess, W.*, Schwarzkopf, L., Hunger, M. & Holle, R.: Competing-risks duration models with correlated random effects: An application to dementia patients' transition histories. Stat. Med. 33, 3919-3931 (2014)


    Malzahn, D.* et al.: Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R. Eur. J. Hum. Genet. 22, 1217-1224 (2014)


    International League Against Epilepsy Consortium on Complex Epilepsies (Gieger, C., Grallert, H., Heinrich, J., Holle, R., Leidl, R., Meisinger, C., Peters, A., Strauch, K.): Genetic determinants of common epilepsies: A meta-analysis of genome-wide association studies. Lancet Neurol. 13, 893-903 (2014)


    Schwarzkopf, L., Hao, Y., Holle, R. & Graessel, E.*: Health care service utilization of dementia patients before and after institutionalization: A claims data analysis. Dement. Geriatr. Cogn. Disord. 4, 195-208 (2014)


    Donath, C.* et al.: Health services utilization by community-dwelling dementia patients and their family caregivers. In: Janssen, C.* ; Swart, E.* ; von Lengerke, T.* [Eds.]: Health Care Utilization in Germany : Theory, Methodology, and Results. New York: Springer, 2014. 193-219


    Wacker, M. et al.: Health-related quality of life and chronic obstructive pulmonary disease in early stages - longitudinal results from the population-based KORA cohort in a working age population. BMC Pulm. Med. 14:134 (2014)


    Kohlboeck, G. et al.: Healthcare use and costs associated with children's behavior problems. Eur. Child Adolesc. Psych. 23, 701-714 (2014)


    Stark, R.G. et al.: Improving care of post-infarct patients: Effects of disease management programmes and care according to international guidelines. Clin. Res. Cardiol. 103, 237-245 (2014)


    Hunger, M. et al.: Longitudinal changes in health-related quality of life in normal glucose tolerance, prediabetes and type 2 diabetes: Results from the KORA S4/F4 cohort study. Qual. Life Res. 23, 2515-2520 (2014)


    Islam, S.* et al.: Mobile phone intervention for increasing adherence to treatment for type 2 diabetes in an urban area of Bangladesh: Protocol for a randomized controlled trial. BMC Health Serv. Res. 14:586 (2014)


    Quinones, P.A. et al.: New potential determinants of disability in aged persons with myocardial infarction: Results from the KORINNA-study. BMC Geriatr. 14:34 (2014)


    Maron, J. et al.: Nimmt die gesundheitliche Ungleichheit zu? Bundesgesundheitsbl.-Gesund. 57, 431-444 (2014)


    Schipf, S.* et al.: Regional differences in the incidence of self-reported type 2 diabetes in Germany: Results from five population-based studies in Germany (DIAB-CORE Consortium) J. Epidemiol. Community Health 68, 1088-1095 (2014)


    Al-Khadra, S. et al.: Secondary prevention medication after myocardial infarction: Persistence in elderly people over the course of 1 year. Drugs Aging 31, 513-525 (2014)


    Laxy, M. & Holle, R.: Selbstmanagement der Patienten: Intensive Einbindung lohnt. Dtsch. Ärztebl. 111, 20-22 (2014)


    Aljutaili, M. et al.: Should health insurers target prevention of cardiovascular disease? A cost-effectiveness analysis of an individualised programme in Germany based on routine data. BMC Health Serv. Res. 14:263 (2014)


    Laxy, M. et al.: The association between patient-reported self-management behavior, intermediate clinical outcomes, and mortality in patients with type 2 diabetes: Results from the KORA-A study. Diabetes Care 37, 1604-1612 (2014)


    Witt, S. et al.: The effectiveness of the cardiovascular disease prevention programme 'KardioPro' initiated by a German sickness fund: A time-to-event analysis of routine data. PLoS ONE 9:e114720 (2014)


    Laxy, M. et al.: The intermediate burden of diabetes mellitus in patients with cardiovascular disease (CVD): A quality adjusted life year (QALY) - analysis based on primary longitudinal data. Value Health 17, A494 (2014)


    Laxy, M., Holle, R., Döring, A., Petter, A. & Hunger, M.: The longitudinal association between weight change and health-related quality of life: The KORA S4/F4 cohort study. Int. J. Public Health 59, 279-288 (2014)


    Tamayo, T.* et al.: Treatment pattern of type 2 diabetes differs in two German regions and with patients' socioeconomic position. PLoS ONE 9:e99773 (2014)


    von Lengerke, T.* et al.: Utilization of primary care physicians by obese men and women: Review for Germany and results from the MONICA/KORA cohorts S3/F3 and S4/F4. In: Janssen, C.* ; Swart, E.* ; von Lengerke, T. [Eds.]: Health Care Utilization in Germany : Theory, Methodology, and Results. New York: Springer, 2014. 221-236


    Fuller, N.R.* et al.: A within-trial cost-effectiveness analysis of primary care referral to a commercial provider for weight loss treatment, relative to standard care - an international randomised controlled trial. Int. J. Obes. 37, 828-834 (2013)


    Schwarzkopf, L., Menn, P., Leidl, R., Graessel, E.* & Holle, R.: Are community-living and institutionalized dementia patients cared for differently? Evidence on service utilization and costs of care from German insurance claims data. BMC Health Serv. Res. 13:2 (2013)


    Doiron, D.* et al.: Data harmonization and federated analysis of population-based studies: The BioSHaRE project. Emerg. Themes Epidemiol. 10:12 (2013)


    Icks, A.* et al.: Drug costs in prediabetes and undetected diabetes compared with diagnosed diabetes and normal glucose tolerance: Results from the population-based KORA survey in Germany. Diabetes Care 36, 53-54 (2013)


    Meisinger, C. et al.: Effects of a nurse-based case management compared to usual care among aged patients with myocardial infarction: Results from the randomized controlled KORINNA study. BMC Geriatr. 13:115 (2013)


    Holle, R., Teuner, C.M. & Wirt, A.*: Epidemiologie. In: Wirth, A.* ; Hauner, H.* [Eds.]: Adipositas - Ätiologie, Folgekrankheiten, Diagnostik, Therapie. Heidelberg [u.a]: Springer, 2013. 25-45


    Holle, R., Hunger, M. & Schunk, M.: Gesundheitsbezogene Lebensqualität bei Personen mit Typ-2-Diabetes: Ergebnisse aus bevölkerungsbasierten Studien in Deutschland. Diabetes Stoffwechs. Herz 22, 313-315 (2013)


    Rietveld, C.A.* et al.: GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 340, 1467-1471 (2013)


    Schunk, M. et al.: Health-related quality of life in adults with and without type 2 diabetes: Results of a pooled analysis of German population-based cohort studies. Diabetologia 56, S57 (2013)


    Teuner, C.M. et al.: Impact of BMI and BMI change on future drug expenditures in adults: Results from the MONICA/KORA cohort study. BMC Health Serv. Res. 13:424 (2013)


    Kowall, B.* et al.: In the grey zone of type 2 diabetes prediction: Can we separate poorly discriminated incident cases and non-cases? Diabetologia 56, S171 (2013)


    Schenkel, J.* et al.: Kostenanalyse telemedizinischer Schlaganfallbehandlung. Veränderung der stationären Behandlungskosten und Pflegekosten am Beispiel des Telemedizinischen Projekts zur integrierten Schlaganfallversorgung in Bayern (TEMPiS). Gesundheitswesen 75, 405-412 (2013)


    Wabitsch, M.* et al.: Medical and psychosocial implications of adolescent extreme obesity - acceptance and effects of structured care short: Youth with Extreme Obesity Study (YES). BMC Public Health 13:789 (2013)


    Claessen, H.* et al.: Medication costs by glucose tolerance stage in younger and older women and men: Results from the population-based KORA survey in Germany. Exp. Clin. Endocrinol. Diabet. 121, 614-623 (2013)


    Grill, E.* et al.: Multi-morbidity and disability, findings from the KORA-Age study. Vortrag: European Workshop on Health and Disability Surveilla, 22-23 November 2012, Berlin, Germany. (2013)


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