Publikationen

Schreiber, M. ; Weigelt, M. ; Karasinsky, A. ; Anastassiadis, K. ; Schallenberg, S. ; Petzold, C. ; Bonifacio, E. ; Kretschmer, K. ; Hommel, A.

Inducible IL-7 hyperexpression influences lymphocyte homeostasis and function and increases allograft rejection.

Front. Immunol. 10:742 (2019)

Freudenberg, K. ; Lindner, N. ; Dohnke, S. ; Garbe, A.I. ; Schallenberg, S. ; Kretschmer, K.

Critical role of TGF-β and IL-2 receptor signalling in Foxp3 inducion by an inhibitor of DNA methylation.

Front. Immunol. 9, accepted (2018)

Fuchs, A. ; Gliwinski, M. ; Grageda, N. ; Spiering, R. ; Abbas, A.K. ; Appel, S. ; Bacchetta, R. ; Battaglia, M. ; Berglund, D. ; Blazar, B. ; Bluestone, J.A. ; Bornhaeuser, M. ; ten Brinke, A. ; Brusko, T.M. ; Cools, N. ; Cuturi, M.C. ; Geissler, E. ; Giannoukakis, N. ; Golab, K. ; Hafler, D.A. ; van Ham, S.M. ; Hester, J. ; Hippen, K. ; Di Ianni, M. ; Ilic, N. ; Isaacs, J. ; Issa, F. ; Iwaszkiewicz-Grzes, D. ; Jaeckel, E. ; Joosten, I. ; Klatzmann, D. ; Koenen, H. ; Van Kooten, C. ; Korsgren, O. ; Kretschmer, K. ; Levings, M. ; Marek-Trzonkowska, N.M. ; Martínez-Llordella, M. ; Miljkovic, D. ; Mills, K.H.G. ; Miranda, J.P. ; Piccirillo, C.A. ; Putnam, A.L. ; Ritter, T. ; Roncarolo, M.G. ; Sakaguchi, S. ; Sanchez-Ramon, S. ; Sawitzki, B. ; Sofronic-Milosavljevic, L. ; Sykes, M. ; Tang, Q. ; Vives-Pi, M. ; Waldmann, H. ; Witkowski, P. ; Wood, K.J. ; Gregori, S. ; Hilkens, C.M.U. ; Lombardi, G. ; Lord, P. ; Martinez-Caceres, E.M. ; Trzonkowski, P.

Minimum information about T regulatory cells: A step toward reproducibility and standardization.

Front. Immunol. 8:1844 (2018)

Chmelova, H. ; Cohrs, C.M. ; Chouinard, J.A. ; Petzold, C. ; Kuhn, M. ; Chen, C. ; Roeder, I. ; Kretschmer, K. ; Speier, S.

Distinct roles of β-cell mass and function during type 1 diabetes onset and remission.

Diabetes 64, 2148-2160 (2015)

Warth, S.C. ; Höfig, K.P. ; Hiekel, A. ; Schallenberg, S. ; Jovanovic, K. ; Klein, L. ; Kretschmer, K. ; Ansel, K.M. ; Heissmeyer, V.

Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation.

EMBO J. 34, 1195-1213 (2015)

Mayer, C.T. ; Lahl, K. ; Milanez-Almeida, P. ; Watts, D. ; Dittmer, U. ; Fyhrquist, N. ; Huehn, J. ; Kopf, M. ; Kretschmer, K. ; Rouse, B. ; Sparwasser, T.

Advantages of Foxp3⁺ regulatory T cell depletion using DEREG mice.

Immun. Inflamm. Dis. 2, 162-165 (2014)

Niebling, J. ; Rünker, A. ; Schallenberg, S. ; Kretschmer, K. ; Kempermann, G.

Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.

F1000 Res. 3:169 (2014)

Petzold, C. ; Steinbronn, N. ; Gereke, M. ; Strasser, R.H. ; Sparwasser, T. ; Bruder, D. ; Geffers, R. ; Schallenberg, S. ; Kretschmer, K.

Fluorochrome-based definition of naturally occurring Foxp3⁺ regulatory T cells of intra- and extrathymic origin.

Eur. J. Immunol. 44, 3632-3645 (2014)

Vahl, J.C. ; Drees, C. ; Heger, K. ; Heink, S. ; Fischer, J.C. ; Nedjic, J. ; Ohkura, N. ; Morikawa, H. ; Poeck, H. ; Schallenberg, S. ; Rieß, D. ; Hein, M.Y. ; Buch, T. ; Polic, B. ; Schönle, A. ; Zeiser, R. ; Schmitt-Gräff, A. ; Kretschmer, K. ; Klein, L. ; Korn, T. ; Sakaguchi, S. ; Schmidt-Supprian, M.

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

Immunity 41, 722-736 (2014)

Wieduwild, R. ; Lin, W. ; Boden, A. ; Kretschmer, K. ; Zhang, Y.

A repertoire of peptide tags for controlled drug release from injectable noncovalent hydrogel.

Biomacromolecules 15, 2058-2066 (2014)

Xiao, S. ; Yosef, N. ; Yang, J. ; Wang, Y. ; Zhou, L. ; Zhu, C. ; Wu, C. ; Baloglu, E. ; Schmidt, D. ; Ramesh, R. ; Lobera, M. ; Sundrud, M.S. ; Tsai, P.Y. ; Xiang, Z. ; Wang, J. ; Xu, Y. ; Lin, X. ; Kretschmer, K. ; Rahl, P.B. ; Young, R.A. ; Zhong, Z. ; Hafler, D.A. ; Regev, A. ; Ghosh, S. ; Marson, A. ; Kuchroo, V.K.

Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.

Immunity 40, 477-489 (2014)

Petzold, C. ; Riewaldt, J. ; Watts, D. ; Sparwasser, T. ; Schallenberg, S. ; Kretschmer, K.

Foxp3⁺ regulatory T cells in mouse models of type 1 diabetes.

J. Diabetes Res. 2013:940710 (2013)

Ritter, P.S. ; Kretschmer, K. ; Pfennig, A. ; Soltmann, B.

Disturbed sleep in bipolar disorder is related to an elevation of IL-6 in peripheral monocytes.

Med. Hypotheses 81, 1031-1033 (2013)

Toker, A. ; Engelbert, D. ; Garg, G. ; Polansky, J.K. ; Floess, S. ; Miyao, T. ; Baron, U. ; Düber, S. ; Geffers, R. ; Giehr, P. ; Schallenberg, S. ; Kretschmer, K. ; Olek, S. ; Walter, J. ; Weiss, S. ; Hori, S. ; Hamann, A. ; Huehn, J.

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

J. Immunol. 190, 3180-3188 (2013)

Heninger, A.K. ; Theil, A. ; Wilhelm, C. ; Petzold, C. ; Huebel, N. ; Kretschmer, K. ; Bonifacio, E. ; Monti, P.

IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells.

J. Immunol. 189, 5649-5658 (2012)

Koristka, S. ; Cartellieri, M. ; Theil, A. ; Feldmann, A. ; Arndt, C. ; Stamova, S. ; Michalk, I. ; Töpfer, K. ; Temme, A. ; Kretschmer, K. ; Bornhäuser, M. ; Ehninger, G. ; Schmitz, M. ; Bachmann, M.

Retargeting of human regulatory T cells by single-chain bispecific antibodies.

J. Immunol. 188, 1551-1558 (2012)

Petzold, C. ; Schallenberg, S. ; Stern, J.N. ; Kretschmer, K.

Targeted antigen delivery to DEC-205⁺ dendritic cells for tolerogenic vaccination.

Rev. Diabet. Stud. 9, 305-318 (2012)

Riewaldt, J. ; Düber, S. ; Boernert, M. ; Krey, M. ; Dembinski, M. ; Weiss, S. ; Garbe, A.I. ; Kretschmer, K.

Severe developmental B lymphopoietic defects in Foxp3-deficient mice are refractory to adoptive regulatory T cell therapy.

Front. Immunol. 3:141 (2012)

Schallenberg, S. ; Petzold, C. ; Tsai, P.Y. ; Sparwasser, T. ; Kretschmer, K.

Vagaries of fluorochrome reporter gene expression in Foxp3⁺regulatory T cells.

PLoS ONE 7:e41971 (2012)

Corten, C. ; Kretschmer, K. ; Kuckling, D.

Novel multi-responsive P2VP-block-PNIPAAm block copolymers via nitroxide-mediated radical polymerization.

Beilstein J. Org. Chem. 6, 756-765 (2010)

Feuerer, M. ; Hill, J.A. ; Kretschmer, K. ; von Boehmer, H. ; Mathis, D. ; Benoist, C.

Genomic definition of multiple ex vivo regulatory T cell subphenotypes.

Proc. Natl. Acad. Sci. U.S.A. 107, 5919-5924 (2010)

Petzold, C. ; Riewaldt, J. ; Koenig, T. ; Schallenberg, S. ; Kretschmer, K.

Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.

Rev. Diabet. Stud. 7, 47-61 (2010)

Schallenberg, S. ; Tsai, P.Y. ; Riewaldt, J. ; Kretschmer, K.

Identification of an immediate Foxp3^- precursor to Foxp3⁺ regulatory T cells in peripheral lymphoid organs of nonmanipulated mice.

J. Exp. Med. 207, 1393-1407 (2010)

Stern, J.N. ; Keskin, D.B. ; Kato, Z. ; Waldner, H. ; Schallenberg, S. ; Anderson, A.C. ; von Boehmer, H. ; Kretschmer, K. ; Strominger, J.L.

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells.

Proc. Natl. Acad. Sci. U.S.A. 107, 17280-17285 (2010)

Cao, Z. ; Wara, A.K. ; Icli, B. ; Sun, X. ; Packard, R.R. ; Esen, F. ; Stapleton, C.J. ; Subramaniam, M. ; Kretschmer, K. ; Apostolou, I. ; von Boehmer, H. ; Hansson, G.K. ; Spelsberg, T.C. ; Libby, P. ; Feinberg, M.W.

Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4⁺ CD25^- T cells and T regulatory cells.

J. Biol. Chem. 284, 24914-24924 (2009)

Düber, S. ; Hafner, M. ; Krey, M. ; Lienenklaus, S. ; Roy, B. ; Hobeika, E. ; Reth, M. ; Buch, T. ; Waisman, A. ; Kretschmer, K. ; Weiss, S.

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells.

Blood 114, 4960-4967 (2009)

Nolting, J. ; Daniel, C. ; Reuter, S. ; Stuelten, C. ; Li, P. ; Sucov, H. ; Kim, B.G. ; Letterio, J.J. ; Kretschmer, K. ; Kim, H.J. ; von Boehmer, H.

Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines.

J. Exp. Med. 206, 2131-2139 (2009)

IPI Institut für die Erforschung pankreatischer Inselzellen
Paul-Langerhans-Institut Dresden

Publikationen

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Kontakt

IPI Institut für die Erforschung pankreatischer Inselzellen Paul-Langerhans-Institut Dresden

Publikationen

Leitung

Kontakt

IPI Institut für die Erforschung pankreatischer Inselzellen
Paul-Langerhans-Institut Dresden